Navigation Links
Circadian rhythms have profound influence on metabolic output, UCI study reveals
Date:3/19/2012

ching implications for human illness and aging, and it is likely vital for proper metabolism," he said. Study results appear this week in the early online edition of the Proceedings of the National Academy of Sciences.

"By identifying the relationship between metabolites and the body clock, we have taken a first step toward a better understanding of how nutrients interact with our metabolism, giving researchers a new opportunity to spot the optimal times for us to get the fullest benefits from the foods we eat and the medications we take," added Kristin Eckel-Mahan, a UCI postdoctoral researcher in biological chemistry and study co-author.

Working with Metabolon Inc., Sassone-Corsi and Eckel-Mahan created the first liver metabolome the full set of metabolites. With this information, they partnered with Pierre Baldi, director of UCI's Institute for Genomics & Bioinformatics, and his graduate student Vishal Patel to analyze the data and build CircadiOmics, a Web-based data system that provides detailed profiles of the metabolites and related genes in the liver and the underlying networks through which they interact. The CircadiOmics address is http://circadiomics.igb.uci.edu.

"Within CircadiOmics, we were able to integrate this circadian metabolite data with multiple other data sources to generate the first comprehensive map of the liver metabolome and its circadian oscillations and develop regulatory hypotheses that have been confirmed in the laboratory," said Baldi, Chancellor's Professor of computer science. "CircadiOmics is being expanded with metabolic data about other tissues and conditions and will be invaluable to further our understanding of the interplay between metabolism and circadian rhythms in healthy and diseased states."


'/>"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
Source:Eurekalert

Page: 1 2

Related biology news :

1. How exposure to irregular light affects plant circadian rhythms
2. Differences in jet lag severity could be rooted in how circadian clock sets itself
3. Circadian clocks in a blind fish
4. Manipulating plants circadian clock may make all-season crops possible
5. A sleep strategy commonly used by night nurses throws off their circadian clocks
6. Circadian rhythms spark plants ability to survive freezing weather
7. UNC scientists pinpoint link between light signal and circadian rhythms
8. Circadian rhythms: Their role and dysfunction in affective disorder
9. Light, circadian rhythms affect vast range of physiological, behavioral functions
10. Texas A&M researchers find new mechanism for circadian rhythm
11. MicroRNAs grease the cells circadian clockwork
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... intake, health and quality of life of older adults ... the University of Waterloo receiving close to $1.5 million ... (CIHR). , Professor Heather Keller, of the Faculty ... research chair in nutrition and aging, will receive $979,000 ... in long-term care homes are poorly nourished. The project ...
(Date:8/21/2014)... to Wednesday, Oct. 18-22, 2014 , WHERE: ... Drive, San Diego, CA 92101 , WHAT: ... presentations of the latest research in human genetics. ... featuring high-scoring abstracts on rare genetic variants in ... and treatment for sun sensitivity (Saturday, Oct. 18, ...
(Date:8/21/2014)... University have developed a novel and versatile modeling strategy ... creating new materials as well as for studying polyelectrolytes, ... us to model much larger and more complex polyelectrolyte ... Nan Li, lead author of a paper on the ... of Materials Science and Engineering. "This is a big ...
Breaking Biology News(10 mins):Grants will fund landmark aging research at Waterloo 2American Society of Human Genetics 2014 Annual Meeting 2Researchers develop models to study polyelectrolytes, including DNA and RNA 2
... products used in consumer goods end up unchanged in ... the environment and human health, researchers from the Autonomous ... to effectively predict what will happen to current and ... are increasingly diverse and increasingly used, are "partially" metabolised ...
... University of Minnesota discovery may help bone cancer patients ... published in the September issue of Bone . ... aggressiveness of the disease can vary from patient to ... patients respond remarkably well to conventional therapies. Their disease ...
... 27, 2011) SomaLogic, Inc. and New England Biolabs, ... an exclusive licensing agreement whereby SomaLogic will provide specific ... and future NEB nucleic acid amplification and polymerase chain ... binding reagents based on chemically modified "aptamers," or short ...
Cached Biology News:New model predicts environmental effect of pharmaceutical products 2U researchers look to dogs to better understand intricacies of bone cancer 2
(Date:8/22/2014)... August 22, 2014 Ophthalmic drug ... interesting and challenging endeavors as the anatomy, physiology ... properties to the foreign substances. Ocular drug delivery ... self medication and minimal use of needles; also ... drugs and provides specific targeting within the ocular ...
(Date:8/22/2014)... The AMA is pleased to share with ... that Alaska Governor Sean Parnell has signed House Bill ... use of Unmanned Aircraft Systems and the continuation of ... that it is, “An Act relating to unmanned aircraft ... aircraft system.” It defines State of Alaska laws regarding ...
(Date:8/21/2014)... , Aug. 21, 2014  BioSpecifics Technologies ... company developing first in class collagenase-based products marketed ... CCH) in the U.S. and XIAPEX ® ... results from a randomized, double-blind Phase 2a study ... or edematous fibrosclerotic panniculopathy. The results showed that ...
(Date:8/21/2014)... Dallas, Texas (PRWEB) August 21, 2014 ... Global Seaweed Fertilizer Industry” is a professional ... Fertilizer market. The report provides basic Seaweed ... application, and industry chain structure as well ... international market analysis, including domestic market as ...
Breaking Biology Technology:Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 4State of Alaska Signs Unmanned Aircraft Systems Bill 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 3
... already lives in areas struggling to keep up with the ... double. Some countries have met the challenge by tapping into ... such as the much-depleted Jordan River have demonstrated, many ... Yale University study argues that seawater desalination should play an ...
... Genetics, Inc. (OTCQB: ILIU) announced today that it will ... at 9:30 a.m. EDT to discuss the Company,s second quarter ... (domestic) or 631-291-4550 (international). The live Webcast and replay access ... of Interleukin Genetics, Inc.,s Website at http://www.ilgenetics.com . ...
... SynCo Bio Partners B.V., one of the ... aseptic filling facility is again fully operational and SynCo has ... clients after the expansion of its Class A zone.   ... an important milestone in SynCo,s strategy in supporting its clients ...
Cached Biology Technology:Better desalination technology key to solving world's water shortage 2Interleukin Genetics, Inc. Announces Conference Call to Discuss Second Quarter 2011 Results 2SynCo Bio Partners Expands the Class A Zone in its Aseptic Filling Facility 2
... fully automated solution for cell culture ... for cell-line maintenance, expansion, harvesting and ... built upon standard, industry proven components: ... configuration capable of both rapid bulk ...
... provide custom microplate coating using advanced automated high throughput microplate ... formats. We can also accommodate virtually any lot size of ... , 8 and 12 ... 384 well microplate, ...
... The Bio-Plex maintenance, calibration, and ... custom 96-well plate used for ... calibration procedures using the Bio-Plex ... plate is for use with ...
... Agencourt offers single pass sequencing ... service is fueled by our high ... 20 million Phred20 bases per day. ... single pass sequencing customers are rapid ...
Biology Products: