Navigation Links
Circadian rhythms have profound influence on metabolic output, UCI study reveals
Date:3/19/2012

ching implications for human illness and aging, and it is likely vital for proper metabolism," he said. Study results appear this week in the early online edition of the Proceedings of the National Academy of Sciences.

"By identifying the relationship between metabolites and the body clock, we have taken a first step toward a better understanding of how nutrients interact with our metabolism, giving researchers a new opportunity to spot the optimal times for us to get the fullest benefits from the foods we eat and the medications we take," added Kristin Eckel-Mahan, a UCI postdoctoral researcher in biological chemistry and study co-author.

Working with Metabolon Inc., Sassone-Corsi and Eckel-Mahan created the first liver metabolome the full set of metabolites. With this information, they partnered with Pierre Baldi, director of UCI's Institute for Genomics & Bioinformatics, and his graduate student Vishal Patel to analyze the data and build CircadiOmics, a Web-based data system that provides detailed profiles of the metabolites and related genes in the liver and the underlying networks through which they interact. The CircadiOmics address is http://circadiomics.igb.uci.edu.

"Within CircadiOmics, we were able to integrate this circadian metabolite data with multiple other data sources to generate the first comprehensive map of the liver metabolome and its circadian oscillations and develop regulatory hypotheses that have been confirmed in the laboratory," said Baldi, Chancellor's Professor of computer science. "CircadiOmics is being expanded with metabolic data about other tissues and conditions and will be invaluable to further our understanding of the interplay between metabolism and circadian rhythms in healthy and diseased states."


'/>"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
Source:Eurekalert

Page: 1 2

Related biology news :

1. How exposure to irregular light affects plant circadian rhythms
2. Differences in jet lag severity could be rooted in how circadian clock sets itself
3. Circadian clocks in a blind fish
4. Manipulating plants circadian clock may make all-season crops possible
5. A sleep strategy commonly used by night nurses throws off their circadian clocks
6. Circadian rhythms spark plants ability to survive freezing weather
7. UNC scientists pinpoint link between light signal and circadian rhythms
8. Circadian rhythms: Their role and dysfunction in affective disorder
9. Light, circadian rhythms affect vast range of physiological, behavioral functions
10. Texas A&M researchers find new mechanism for circadian rhythm
11. MicroRNAs grease the cells circadian clockwork
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... 29, 2014  Securus Technologies, a leading ... solutions for public safety, investigation, corrections and ... exciting enhancements to its THREADS™ product, which ... actionable intelligence and focused leads for investigators. ... technological innovation through identifying and delivering solutions ...
(Date:10/29/2014)... 2014, Beaverton, OR) New research presented at ... Conference in Houston, TX showed for the first ... infection in women using a readily available nutritional ... presented by Dr. Judith A. Smith, Pharm.D., associate ... Reproductive Sciences at The University of Texas Health ...
(Date:10/29/2014)... An overwhelming number of chemicals from household and industrial ... in our bodies. But for most of them, scientists ... Now they,ve taken the first step toward doing that ... most. Their new method is published in the ACS ... F. Wambaugh and colleagues note that the risks to ...
Breaking Biology News(10 mins):Securus Technologies Adds Advanced Features to Its Industry-Leading Investigative Analytics Product 2HPV infections in women eradicated by AHCC, Japanese mushroom extract 2
... of New South Wales have cautioned that more ... to the disinfecting properties of silver nano-particles, increasingly ... nanosilver has effective antimicrobial properties against certain pathogens, ... harmful organisms to rapidly adapt and flourish, a ...
... 8 May 2013 (Geneva, Switzerland) - Strategies for pursuing ... at higher CD4 counts and innovative models for HIV ... programme announced today. , "Functional cures" and the benefits ... this year and the IAS 20I3 conference, the worlds ...
... York City,s Central Park to Golden Gate Park in San ... of carbon, an environmental service with an estimated value of ... Annual net carbon uptake by these trees is ... benefit. In the study published recently in the journal ...
Cached Biology News:Bacteria adapt and evade nanosilver's sting -- new study 2IAS 2013 conference program live online 2IAS 2013 conference program live online 3US urban trees store carbon, provide billions in economic value 2US urban trees store carbon, provide billions in economic value 3US urban trees store carbon, provide billions in economic value 4US urban trees store carbon, provide billions in economic value 5US urban trees store carbon, provide billions in economic value 6
(Date:10/30/2014)... Isis Pharmaceuticals, Inc. (NASDAQ: ISIS ), ... present a company overview at the Nomura Biotechnology Conference on ... Boston, MA. A live webcast ... Media" section of the Company,s website, www.isispharm.com .  A ... hours and will be archived for a limited time. ...
(Date:10/30/2014)... 30, 2014  Regado Biosciences, Inc. (Nasdaq: ... conference call and live audio webcast on Thursday, November ... third quarter 2014 financial results. Interested participants ... (888) 347-1165 for domestic callers or (412) 902-4276 for ... under the investor relations section of the Regado website ...
(Date:10/30/2014)... flooding that devastated a wide swath of Colorado last ... roads and other infrastructure had been upgraded or modernized, ... Colorado Denver. , "People need to understand the importance ... professor of structural engineering at the CU Denver College ... study. "There is an assumption that a bridge will ...
(Date:10/27/2014)... The new research report, “Gas Insulated Switchgear ... (Primary & Secondary), and End-User (Transmission & Distribution, ... Generation) - Trends and Forecasts to 2019”, defines ... forecasting of the market size. , Browse more ... spread through 146 Pages and in-depth TOC on ...
Breaking Biology Technology:Isis Pharmaceuticals to Present at the Nomura Biotechnology Conference 2Regado Biosciences to Provide Third Quarter 2014 Financial Results 2CU Denver study says upgrading infrastructure could reduce flood damage 2Gas Insulated Switchgear Market worth $21,951.9 Million by 2019 - New Report by MarketsandMarkets 2Gas Insulated Switchgear Market worth $21,951.9 Million by 2019 - New Report by MarketsandMarkets 3Gas Insulated Switchgear Market worth $21,951.9 Million by 2019 - New Report by MarketsandMarkets 4
... Inc.,announced today that it has been awarded a ... Research (SBIR) grant, entitled,"Long-Acting Beta Interferon for Multiple ... Stroke (NINDS) of The National,Institutes of Health (NIH). ... the achievement of certain research milestones., George ...
... scientific and business development flexibility, TSX Exchange ... Resverlogix Corp.,("Resverlogix") (TSX:RVX) announced today that it has ... USD$17.3 million debenture., Donald McCaffrey, President and ... volatile and challenging for companies,around the globe. This ...
... begin after markets close at 2:00 p.m. PT ... ... MASI ), the inventor of Pulse CO-Oximetry and,Measure-Through-Motion- and-Low-Perfusion pulse oximetry, today ... 2008 after the market closes on Monday, October 27, 2008., A ...
Cached Biology Technology:Bolder BioTechnology Receives $1.6 million NIH Grant to Continue Development of Multiple Sclerosis Drug 2Resverlogix Eliminates Sixty Percent of Remaining Debt 2Masimo to Report Third Quarter 2008 Financial Results on October 27, 2008 2
... Arrays can be used to test the ... and sera that are commonly used as ... contains spots for 21 different protein preparations ... antibody crossreactivity and species specificity, QC of ...
... the experimental process of determining the nucleotide ... DNA Sequencing is based on Sangers enzymatic ... allows cycle sequencing reactions. The resulting fluorescent ... capillary instrument controlled by a computer and ...
... On-Demand Cytometry The Guava EasyCyte ... laser based multiparameter cytometer with built-in 96-well ... can screen plates of cells and compounds ... manipulating multiple tubes or having the carryover ...
... and finishing services are tailored to ... large-scale 5' screening or full length ... experience with large-scale genome projects and ... ideal cDNA outsourcing solution. In addition, ...
Biology Products: