Navigation Links
Circadian rhythms: Their role and dysfunction in affective disorder
Date:8/30/2010

hms, the stability of mood, and sleep regulation.

How to reset the human biological clock in affective disorders

In clinical practice, sleep disturbances in depression generally can be improved with effective antidepressant medication. However, commonly used modern antidepressants may be sleep-disturbing, particularly early in treatment, often to the extent that a sedative or hypnotic compound has to be prescribed concomitantly (Mayers & Baldwin, 2005). The search for novel antidepressants has focused primarily on drug development, with the role of psychotherapy and cognitive behavioural therapy to help depressive patients being well accepted. Surprisingly though, clinical application of chronobiological research, so called chronotherapeutics, appears not to fit into any conventional category, and is mostly neglected as putative treatment.

Chronotherapeutics

Chronotherapeutics is defined as controlled exposure to environmental stimuli that act on biological rhythms (e.g. light) or direct manipulations of sleep in order to achieve therapeutic effects in the treatment of psychiatric disorders. One major aim of chronotherapeutics is to synchronise impaired circadian rhythms. Today the range of chronotherapeutic indications not only comprises affective disorders such as major depression (seasonal and non-seasonal), bipolar disorder, and premenstrual dysphoric disorder and depression during pregnancy, but also bulimia nervosa, attention-deficit/hyperactivity disorder (ADHD), dementia, Parkinsons disease, and shift work and jet-lag disturbances (Wirz-Justice et al., 2009). Chronotherapeutic elements include light therapy, dark therapy or blue-blocking sunglasses, wake therapy (total or partial sleep deprivation in the second half of the night), phase advance of the sleep-wake cycle, and exogenously administered melatonin.

Light therapy as a zeitgeber has been used to resynchronise disturbed sleep schedules back to
'/>"/>

Contact: Sonja Mak
s.mak@update.europe.at
431-405-5734
European College of Neuropsychopharmacology
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related biology news :

1. Circadian clock may be critical for remembering what you learn, Stanford researchers say
2. UNC study: Tinkering with the circadian clock can suppress cancer growth
3. Two new studies on circadian rhythms
4. MicroRNAs grease the cells circadian clockwork
5. Texas A&M researchers find new mechanism for circadian rhythm
6. Light, circadian rhythms affect vast range of physiological, behavioral functions
7. Women do not recover their muscle strength as fast as men
8. Beetles get by with a little help from their friends
9. Migratory moths may hitch their rides, but theyre anything but drifters
10. IOF calls on European citizens to stand tall and speak out for their bones
11. Rare corals breed their way out of trouble
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... MELBOURNE, Fla. , Aug. 21, 2014 ...  announced that it has agreed to a ... Orlando,s fastest growing Certified ... make  Gabriel Health Institute  an exclusive member ... a result, Binary Biometrics will improve its ...
(Date:8/21/2014)... of the water window? It consists of radiations in ... absorbed by the water in biological tissues. New theoretical ... radiations within the water window. These could be the ... image of the biological samples or to be used ... the physical mechanism needed to efficiently generate the harmonic ...
(Date:8/21/2014)... replicated one of the crucial steps in photosynthesis, opening ... could manufacture hydrogen as a fuel. , "Water is ... prospect to use them to create hydrogen, and do ... the ARC Centre of Excellence for Translational Photosynthesis in ... potential as a zero-carbon replacement for petroleum products, and ...
Breaking Biology News(10 mins):LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3Water window imaging opportunity 2Water and sunlight the formula for sustainable fuel 2
... group of chemical compounds used by a species of ... promising antimalarial properties for humans. The compounds are part ... to battle enemies and that may provide a ... novel analytical process, researchers at the Georgia Institute of ...
... successfully being used in clinical trials to treat patients with ... die, it also forces them to release pro-inflammatory chemokines and ... attack the disease. New research published by BioMed Central,s open ... infected cancer cells secrete proteins which, even when isolated, result ...
... Variations in skin color provide one of the best ... body and should be used to teach evolution in schools, ... level of interest in skin color and for teachers, that ... Nina Jablonski, professor and head, Department of Anthropology, Penn State. ...
Cached Biology News:Antifungal compound found on tropical seaweed has promising antimalarial properties 2Antifungal compound found on tropical seaweed has promising antimalarial properties 3Antifungal compound found on tropical seaweed has promising antimalarial properties 4Skin color: Handy tool for teaching evolution 2Skin color: Handy tool for teaching evolution 3
(Date:8/20/2014)... of patented university inventions licensed to biotechnology firms ... commercialization. To open these roadblocks, the researchers suggest ... the discovery stage could lead to faster commercialization ... derived from discoveries made in university laboratories and ... during clinical trials, which have a high failure ...
(Date:8/20/2014)... the first time, chemists have succeeded in measuring vibrational ... resolution. The study reveals how vibration of a single ... , The study was performed at the University ... the University of Jyvskyl works as a visiting fellow ... the study. The second team was lead by Professor ...
(Date:8/20/2014)... Livermore, California (PRWEB) August 20, 2014 ... to develop and apply the most complete climate ... challenging and demanding climate change issues. , Eight ... combining forces with the National Center for Atmospheric ... in the new effort. Other participating national laboratories ...
(Date:8/20/2014)... BOSTON , Aug. 20, 2014  PAREXEL International ... it will be presenting at the Baird Healthcare Conference ... President and Chief Financial Officer, will be making a ... p.m. EDT on Wednesday, Sept. 3, 2014. ... through the "Investors" section of PAREXEL,s website at ...
Breaking Biology Technology:Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3Seeing a molecule breathe 2New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3PAREXEL International To Present At Baird Healthcare Conference 2
... Milwaukee, were incredibly bullish , ,Plymouth, Wis. - ... pejorative phrases like Rust Belt, Wisconsin got a much needed ... its December 8, 2003 edition. In an interview with Jeff ... he states that the U.S. is about to enter the ...
... the total number of business incubators located in the ... job creation as well, according Thomas Lyons, Professor of ... addressed an audience at the Wisconsin Small Business ... MGE Innovation Center , a business incubator located in ...
... nothing in record numbers. , ,In 2003, an estimated 5 ... as LiveJournal , Movable Type , and Weblogger ... a New Year's resolution. , ,A November study of eight ... 20 percent of all blogs (short for "Web logs") are abandoned ...
Cached Biology Technology:Wisconsin Manufacturing Poised For a Barrons Bounce 2Wisconsin Manufacturing Poised For a Barrons Bounce 3Business Incubators Grow Economy and Jobs 2Business Incubators Grow Economy and Jobs 3Who Gives a Blog? 2
Immunogen GST fusion protein corresponding to full-length rat JNK3/ SAPK1b. Quality Assurance Routinely evaluated by immunoblot. Stability 2 years at -20°C from date of shipment GenBank A...
... ViaSure Kit is used in conjunction with the ... cells automatically. The ViaSure Staining Reagent uses ... Acridine Orange and Ethidium Bromide to identify live ... while the EasyCount Slide 6 Multi-well Slide ...
... a powerful yet simple technology for labeling ... kit provides the heterobifunctional linkers SFB and ... efficiencies. It enables conjugation of various tags ... with a variety of proteins. , ...
... activated carrier proteins to simplify the ... Activated Carrier Proteins are commonly used ... a heterobifunctional cross-linker (Sulfo-SMCC). This activation ... protein. Thus allowing the maleimide-activated ...
Biology Products: