Navigation Links
Circadian rhythms: Their role and dysfunction in affective disorder
Date:8/30/2010

All humans are synchronised to the rhythmic light-dark changes that occur on a daily basis. Rhythms in physiological and biochemical processes and behavioural patterns persist in the absence of all external 24-hour signals from the physical environment, with a period that is close to 24 hours. These rhythms are referred to as circadian, from the Latin circa diem (about a day), and are attributable to internal biological clocks, driven by a major circadian pacemaker in the brain. The circadian pacemaker is entrained each day to the 24-hour solar cycle, which is the major zeitgeber (literally time-giver). Other zeitgebers are food intake, activity, or social cues, e.g. the alarm clock. Good temporal entrainment allows for optimal performance at the right time of the day, because being able to anticipate future tasks allows the appropriate physiological and psychological preparation. However, our modern society often imposes deviations from the regular work-rest-scheme, as in shift work, which results in problems with entrainment.

Failure to adapt to environmental and societal time cues leads to misalignment of internal biological clocks. This dysentrainment comes with enhanced risk of errors and accidents, loss of productivity, and health risks such as increased propensity for cancer, depression, sleep disturbances, gastrointestinal, metabolic and cardiovascular disorders, decreased immune responses and even life span. Hence, people with circadian rhythm disruption caused by shift work often develop glucose intolerance, diabetes and hypertension, and maybe cancer. The recent discovery of the core molecular circadian clock machinery has dramatically increased interest in the impact of circadian dysregulation on mental and physical health.

Molecular basis of circadian rhythms

Circadian rhythms are directed by a master biological clock in a specific brain structure of the hypothalamus called the suprachiasmatic nuclei (SCN). Apa
'/>"/>

Contact: Sonja Mak
s.mak@update.europe.at
431-405-5734
European College of Neuropsychopharmacology
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related biology news :

1. Circadian clock may be critical for remembering what you learn, Stanford researchers say
2. UNC study: Tinkering with the circadian clock can suppress cancer growth
3. Two new studies on circadian rhythms
4. MicroRNAs grease the cells circadian clockwork
5. Texas A&M researchers find new mechanism for circadian rhythm
6. Light, circadian rhythms affect vast range of physiological, behavioral functions
7. Women do not recover their muscle strength as fast as men
8. Beetles get by with a little help from their friends
9. Migratory moths may hitch their rides, but theyre anything but drifters
10. IOF calls on European citizens to stand tall and speak out for their bones
11. Rare corals breed their way out of trouble
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... of people in the United States have a circulatory ... can be painful and may even require surgery in ... muscle wasting and, in turn, limb amputation. , At ... (UTHealth) Medical School, scientists tested a non-surgical preventative treatment ... was associated with increased blood circulation. Their proof-of-concept ...
(Date:7/28/2014)... at Yale School of Medicine have pinpointed a mechanism in ... levels in the blood, linking it to both type 1 ... July 28 issue of Proceedings of the National Academies ... endopeptidase enzyme located in a part of the hypothalamus ... steps in motion that control glucose levels in the blood," ...
(Date:7/28/2014)... Eight of the top 10 U.S. cities that have ... public inconveniences as frequent road closures, overwhelmed storm drains ... a new NOAA technical report. , This nuisance flooding, ... three U.S. coasts, between 300 and 925 percent since ... Nuisance Flood Frequency Changes around the United States, also ...
Breaking Biology News(10 mins):Scientists discover genetic switch that can prevent peripheral vascular disease in mice 2Glucose 'control switch' in the brain key to both types of diabetes 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 3
... be tough, but scientists have found a Yellowstone National ... simple one-celled algae called Cyanidioschyzon -- thrives ... occurs naturally around hot springs, said Tim McDermott, professor ... at Montana State University. Cyanidioschyzon could ...
... is a commonly used indicator organism for detecting the ... of E. coli as an indicator organism has ... this important microorganism in groundwater environments. Commonly only a single ... studies, yet research has shown that a significant amount of ...
... March 6, 2009 -- As the first plant life ... earth, bryophytes offer a unique opportunity for researchers to ... three varieties of bryophites (liverworts, hornworts, and mosses) have ... local environments, but with the recent effects of climate ...
Cached Biology News:Montana State team finds Yellowstone alga that detoxifies arsenic 2Montana State team finds Yellowstone alga that detoxifies arsenic 3Transport behavior of E. coli varies depending on manure source 2How increased UV exposure impacts plants 2
(Date:7/28/2014)... Boston, MA (PRWEB) July 28, 2014 ... with two researchers to further develop potential treatments for ... brain tumor, in combination with their patented vaccine platform, ... and Duke University, are based on the work of ... of Neurosurgery at The Preston Robert Tisch Brain Tumor ...
(Date:7/28/2014)... 28, 2014 It’s a hard truth: Nearly ... to further their post-secondary education are failing to obtain a ... this year. And according to an analysis by The ... veteran students’ uninformed choice of college majors, which leads to ... the study: Some 51.7 percent of post-9/11 veterans using ...
(Date:7/28/2014)... COLLEGE STATION, Texas , July 28, 2014 /PRNewswire/ ... will be a 177-key, 4-star boutique hotel in the heart ... , Texas.  Photo - http://photos.prnewswire.com/prnh/20140725/130455 ... the first hotel within ATLAS , The ... mixture of standard rooms and suites, a sleek restaurant and bar, ...
(Date:7/26/2014)... (PRWEB) July 26, 2014 Canada ... key market data on the Canada Endoscopy Visualization ... of US dollars, volume (in units) and average ... High-End Endoscopy Visualization Systems, Mid-Range Endoscopy Visualization Systems ... Report at http://www.marketresearchreports.biz/analysis/213254 . , The report ...
Breaking Biology Technology:String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 2String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 3String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 4Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 2Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 3Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 4Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 2Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 3Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 3Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 5
... 1938 to the impact of the Krakatoa eruption of 1883, ... of extreme weather. Now an international team of climatologists have ... 1871 to the present day, and from the earth,s surface ... Reanalysis Project, outlined in the Quarterly Journal of the ...
... done and now they,ve done it. What,s more, they did ... U.S. Department of Energy (DOE),s Lawrence Berkeley National Laboratory (Berkeley ... the first experimental demonstration of GRIN for gradient index ... a wide range of exotic optics, including superfast computers based ...
... Amgen (Nasdaq: AMGN ) today announced that it ... results on Monday, Jan. 24, 2011 after the close of ... conference call with the investment community at 2:00 p.m. Pacific ... Sharer, chairman and chief executive officer, and other members of ...
Cached Biology Technology:The 20th Century Reanalysis Project: A time machine for climate scientists 2The 20th Century Reanalysis Project: A time machine for climate scientists 3GRIN plasmonics 2GRIN plasmonics 3GRIN plasmonics 4Amgen Announces Webcast of 2010 Fourth Quarter and Full Year Financial Results 2
... use spatulas have been designed to save ... for those interested in eliminating the recycling ... spatula is individually packaged, RNase/DNase free, non-pyrogenic ... a new product number, created to easily ...
... been designed to save time and provide ... in eliminating the recycling and resterilizing necessary ... packaged, RNase/DNase free, non-pyrogenic and antistatic. Linkage: ... number, created to easily match Cornings product ...
... spatulas have been designed to save time ... those interested in eliminating the recycling and ... is individually packaged, RNase/DNase free, non-pyrogenic and ... new product number, created to easily match ...
... a base medium for preparation of minimal and ... but does not contain amino acids. Both bulk ... pouch contains reagents to prepare 500 ml of ... of 10X YNB for S. cerevisiae media. Store ...
Biology Products: