Navigation Links
Cigarette smoking may accelerate disability in those with MS
Date:10/13/2007

BUFFALO, N.Y. -- Persons with multiple sclerosis who smoke risk increasing the amount of brain tissue shrinkage, a consequence of MS, and the subsequent severity of their disease, new research conducted at the Buffalo Neuroimaging Analysis Center (BNAC) at the University at Buffalo has shown.

The results are based on magnetic resonance images (MRIs) of smokers and nonsmokers in 368 MS patients treated in UBs Jacobs Neurological Institute, the universitys Department of Neurology in its School of Medicine and Biomedical Sciences.

Results of the research were presented today (Oct. 13, 2007) at the 23rd Congress of the European Committee for the Treatment and Research in Multiple Sclerosis in Prague, Czech Republic.

Cigarette smoke has many properties that are toxic to the central nervous system, and cigarette smoking has been linked to higher susceptibility and risk of progressive multiple sclerosis, said Robert Zivadinov, M.D., Ph.D., UB professor of neurology, director of the BNAC and first author on the study.

Interactions between cigarette smoking and genetic and immunologic factors may point to mechanisms in disease pathogenesis. No previous studies have investigated differences in MRI characteristics between MS cigarette smokers and MS nonsmokers, he said.

The study included patients from the three most common forms of MS: 253 had relapsing-remitting MS -- acute attacks with full or partial recovery; nine had primary-progressive MS -- steady worsening from onset; and 90 had secondary-progressive MS, characterized by occasional attacks and sustained progression. Another 16 participants had experienced their first MS onset.

Patients ranged in age from 35-55 years, and had been living with MS for an average of 13 years. The Expanded Disability Status Scale (EDSS), an average number derived from measures of various functions of the central nervous system based on scales ranging from 0 to 10, was 3.1. The higher the number, the greater
'/>"/>

Contact: Lois Baker
ljbaker@buffalo.edu
716-645-5000 x1417
University at Buffalo
Source:Eurekalert

Page: 1 2

Related biology news :

1. Cigarette smoke blocks cell repair mechanism, University of Florida study shows
2. Halving daily cigarette quota has no health benefit
3. Cigarette smoking impedes tendon-to-bone healing
4. Re-analysis of cigarettes confirms tobacco companies increased addictive nicotine 11 percent
5. New cigarette designs dont offer lower predicted cancer risks
6. Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring
7. Research shows smoking adds a decade to reproductive age of IVF patients
8. OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies
9. Indias smoking gun: Dino-killing eruptions
10. Smoking damages key regulatory enzyme in the lung
11. Alcoholism, smoking and genetics among Plains American Indians
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2015)... 2015 Biometry authentication provider KeyLemon today ... solution one face in. Logo ... face in, entering the expanding biometric authentication market ... biometric answer to the password problem. With advanced ... with KeyLemon, one face in allows users to ...
(Date:6/23/2015)... GARDENS, Fla. , June 23, 2015 ... identity management and authentication solutions, today announced enhanced ... strong, multi-factor authentication solution.  The enhancements build ... use of the DigitalPersona Altus platform and ... reader compatibility. In today,s environment ...
(Date:6/17/2015)... Germany , June 17, 2015 ... today launched new Investigator ® STR assay kits for ... the United States . The new genetic fingerprint kits ... markers (short tandem repeats or STRs) for DNA matching. They ... quality of DNA in each sample, a novel QIAGEN technology ...
Breaking Biology News(10 mins):KeyLemon Announces Partnership With Biometric Password Solution onefacein 2Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 4QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 5
... plants are all around us and are phenomenally successfulbut how ... they come from? This question bothered Darwin and others ... Botanical Journal of the Linnean Society indicates that ... Sherwin Carlquist, a research botanist at the Santa Barbara Botanic ...
... is developing into one of the nation,s premiere tools in ... reservoirs, such as depleted oil and natural gas reservoirs, can ... a major greenhouse gas. CO2 would be captured at coal ... CO2, and transported by pipeline to reservoirs where it would ...
... million grant to North Carolina State University will allow ... how genes impact the type and amount of "glue," ... of lignin, which binds fibers together to form wood, ... biofuels and construction materials. The National Science Foundation ...
Cached Biology News:Department of Energy supports carbon sequestration research, University of Miami receives $1.7 million 2NC State receives NSF grant to discover plant 'switchboards' 2NC State receives NSF grant to discover plant 'switchboards' 3
(Date:6/30/2015)... ... June 30, 2015 , ... Smarter Alloys ... a revolutionary new archwire that allows orthodontists to simultaneously apply different forces to ... efficacy of SmartArch. “We’re thrilled about taking SmartArch one step closer to commercial ...
(Date:6/29/2015)... ... June 29, 2015 , ... ... around 19% during the forecast period (2015 to 2020). The market is mainly ... government and corporate funding for R&D. However, lack of adequate healthcare and research ...
(Date:6/29/2015)... According to a new market research report "Aptamers Market ... by Technology (SELEX, Other Technologies), by End Users (Academic Research ... 2020", published by MarketsandMarkets, the global Aptamers Market is expected ... 2015, at a CAGR of 17.89%. Browse ... igures spread through 125 P ages ...
(Date:6/26/2015)... June 26, 2015  SeraCare Life Sciences, a ... today announced that it has signed a Cooperative ... Cancer Institute (NCI), part of the National Institutes ... controls for cancer assays.  The CRADA will investigate ... quantitate control DNA biosynthetics spiked into a genomic ...
Breaking Biology Technology:New case studies for SmartArch orthodontic archwire paves way to product launch later this year 2Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 2Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 4Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 5Aptamers Market Worth $244.93 Million by 2020 2Aptamers Market Worth $244.93 Million by 2020 3Aptamers Market Worth $244.93 Million by 2020 4SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 2SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 3
... Therapeutics Corporation (Nasdaq: UTHR ) announced today ... annual financial results before market open on Tuesday, February ... Tuesday, February 17, 2009, at 9:00 a.m. Eastern Time. ... international callers dialing 719-325-4753. A rebroadcast of the ...
... or Phase 0 clinical testing has been gaining ... the drug development process in the years to ... preclinical testing and technology dependence is also expected ... growth opportunities in this sector.(Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )"There ...
... BASEL, Switzerland, Feb. 10 Syngenta today announced that ... Rice Research Institute (ARRI) of Anhui Academy of Agricultural ... conducting laboratory and field tests of novel gene functions ... optimization in key crops such as corn and soybean. ...
Cached Biology Technology:Frost & Sullivan Sees Microdosing as Compelling Advantage for Big Pharma 2Frost & Sullivan Sees Microdosing as Compelling Advantage for Big Pharma 3Syngenta Enters Into Research Collaboration With Anhui Academy, China 2Syngenta Enters Into Research Collaboration With Anhui Academy, China 3
Request Info...
Sprague Dawley rats, 7-8 weeks of age, mixed gender; collected by exsanguination in Alsever's solution at 1:2 dilution...
2-min, single-step add-mix-measure assay for luciferase expression and HTS in mammalian cells. Linear detection range: 2 fg to 46 ng luciferase....
... Error-free cloning of BAC (100+kb), fosmid (40kb), ... insert stability than any othe BAC vector. ... high yields and easy recombinant DNA purification. ... transcription-free (pSMART VC) vectors for the highest ...
Biology Products: