Navigation Links
Cigarette smoking increases colorectal cancer risk
Date:12/2/2009

PHILADELPHIA New study results strengthen the evidence that people who smoke cigarettes over a long period of time have an increased risk for developing colorectal cancer, even after adjusting for other risk factors.

"This provides one more reason not to smoke, or to quit as soon as possible," said senior author Michael J. Thun, M.D., M.S., vice president emeritus, epidemiology and surveillance research at the American Cancer Society. "Colorectal cancer should be added to the list of cancers caused by smoking."

Findings are published in the December issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, as part of a special focus on tobacco.

Thun and colleagues tested the association between long-term cigarette smoking and colorectal cancer after adjusting for multiple other factors that are generally associated with risk, including screening. From 1992 through 2005 the researchers followed almost 185,000 participants aged 50 to 74 years old; participants described their behaviors and medical conditions.

Participants who smoked cigarettes for 40 or more years, or who did not quit before age 40, had a 30 percent to 50 percent increased risk of developing colon or rectal cancer during the follow-up, even in analyses that adjusted for 13 other potential risk factors, according to Thun. After 13 years of follow-up, the researchers identified 1,962 cases of invasive colorectal cancer.

While previous large studies conducted in long-term smokers showed similar results, Thun stated that this study is the first to control for screening and all of the suspected risk factors for colorectal cancer, such as alcohol consumption, physical inactivity and consumption of red or processed meat.

"These findings contributed to the evidence recently reviewed by the International Agency for Research on Cancer (IARC) in October of this year," Thun said. "IARC upgraded the evidence that smoking causes colorectal cancer from 'limited' to 'sufficient'."

This IARC reclassification brings the number of cancer organ sites causally related to cigarette use to 17, which includes cancers of the oral cavity, pharynx, nasopharynx, nasal cavity and paranasal sinuses, larynx, lung, esophagus (both squamous cell and adenocarcinoma), stomach, colorectum, liver, pancreas, kidney (both renal cell and transitional cell carcinoma), urinary bladder and lower urinary tract, uterine, cervix, and myeloid leukemia.


'/>"/>

Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research
Source:Eurekalert  

Related biology news :

1. Head and neck cancer survivors who use alcohol and cigarettes have increased death risk
2. Exposure to secondhand cigarette smoke over a lifetime increased breast cancer risk later in life
3. Allergy season: Cigarettes to the rescue?
4. Smoke from cigarettes, cooking oil, wood, shift male cardiovascular system into overdrive
5. Smoke from cigarettes, cooking oil, wood, shift male cardiovascular system into overdrive
6. 1 drug may help people both lay down the drink and put out the cigarette
7. If your first cigarette gave you a buzz and you now smoke, a gene may be to blame
8. Scientists discover how cigarette smoke causes cancer: Study points to new treatments, safer tobacco
9. Cigarette after Valentine snuggle deadlier for some
10. Cigarette smoke, alcohol damage hearts worse as combo
11. Cigarette smoking may accelerate disability in those with MS
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cigarette smoking increases colorectal cancer risk
(Date:1/20/2016)... A market that just keeps on growing. ... explosion in genomics knowledge. Learn all about it in ... of dynamic trends are pushing market growth and company ... pharmacogenomics - pathogen evolution - next generation sequencing - ... understanding of the role of genetic material in Disease ...
(Date:1/20/2016)... JOSE, Calif. , Jan. 20, 2016 /PRNewswire/ ... developer of human interface solutions, today announced sampling ... controller solution for wearables and small screen applications ... such as printers. Supporting round and rectangular shapes, ... S1423 offers excellent performance with moisture on screen, ...
(Date:1/15/2016)... SAN JUAN, Puerto Rico , Jan. 15, 2016 ... forcing companies big and small to find new ways ... data driven culture. iOS and ... their device based on biometrics, transforming it into a ... can request that users swipe their fingerprint on their ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... 10, 2016  Matchbook, Inc., a company specializing ... biotech companies, announced today the appointment of ... Jim brings nearly 25 years of experience in ... spent nearly two decades in executive level roles ... at Genzyme and, most recently headed global logistics ...
(Date:2/10/2016)... ... 2016 , ... SonaCare Medical, LLC reports the introduction of ... monitoring. The inaugural launch of this new technology occurred over the course of ... to a HIFU technical expert at SonaCare Medical headquarters. , Sonalink allows ...
(Date:2/10/2016)... ... ... Cenna Bioscience Inc., an emerging biopharmaceutical company focused on the discovery and ... been selected to present at the Cavendish Global Health Impact Forum taking place February ... of the Forum is to help family offices and foundations develop and implement their ...
(Date:2/9/2016)... ... February 08, 2016 , ... ... Baruch S. Blumberg Institute at the Pennsylvania Biotechnology Center of Bucks County, 3805 ... The Commonwealth Medical College (TCMC) will hold an open house for participants to ...
Breaking Biology Technology: