Navigation Links
Cigarette after Valentine snuggle deadlier for some
Date:2/12/2008

The proverbial cigarette after a Valentines Day snuggle can prematurely end a love affair, as new evidence emerges that a common defect in a gene significantly increases a smokers risk of an early heart attack. Researchers say that as much as 60 to 70 percent of the population has a gene defect that delivers a one-two punch to smokers: In a recent published study, heavy smokers with this common gene variant experienced a heart attack around the age of 52.

Weve all heard the stories: Someones great-uncle has smoked three packs of cigarettes since he was 14, and now, at the age of 88, hes living a fine, healthy life, said Arthur Moss, M.D., director of the Heart Research Follow-up Program at the University of Rochester Medical Center. Contrast that with the 52-year old neighbor, who also was a heavy smoker, and just last week, dropped dead from a heart attack. Why is it that some smokers seem unaffected by their habit and even outlive the healthiest individuals, while many other smokers suffer significant cardiac events at a relatively young age? We think we now know why.

According to Moss, the answer lies is a common deviation of the gene CETP (cholesteryl ester transfer protein), a protein found in all people that controls cholesterol metabolism. Smokers with a common form of this gene are likely to suffer a heart attack 12 years earlier than a non-smoker, while smokers who do not carry this variant appear to be protected and have the same risk of heart attack as non-smokers.

While genes have long been linked to diseases, its only been recently that researchers have been able to begin unraveling the intricate interplay between genes and the environment. By understanding how certain environmental factors such as diet, chemicals and even smoking can influence how well or not a particular gene works, scientists hope to provide new approaches to help decrease a persons risk of disease.

In this case, researchers zeroe
'/>"/>

Contact: Germaine Reinhardt
germaine_reinhardt@urmc.rochester.edu
585-275-6517
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Cigarette smoke, alcohol damage hearts worse as combo
2. Cigarette smoking may accelerate disability in those with MS
3. After more than 100 years apart, webworms devastate New Zealand parsnips
4. Twinkle after-effect can help retinal patients detect vision loss quickly and cheaply
5. After drought, ponds keep up with the Joneses
6. Expecting an afternoon nap can reduce blood pressure
7. Simulation reveals how body repairs balance after damage
8. Clearance of hepatitis C viral infection after liver transplantation
9. Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... "mouse TRAP" to capture the early signs of kidney ... the Journal of Clinical Investigation . Their new ... extract cellular and genetic information from a variety of ... Institute for Medical Research in 2008, TRAP involves attaching ... of the cell type of interest. Scientists can then ...
(Date:7/11/2014)... from the Max Planck Institute for Medical Research in ... understanding photosynthesis, the process by which the Earth first ... and which is therefore crucial for all higher forms ... the first direct visualization of a crucial event in ... specific protein complex, photosystem II, splits water into hydrogen ...
(Date:7/11/2014)... division of the striatum is also involved in ... of substance P in the striatal marginal division ... his team, College of Biophotonics, South China Normal ... P receptor, neurokinin 1 was highly expressed in ... rats. Unilateral or bilateral injection of an antisense ...
Breaking Biology News(10 mins):A first direct glimpse of photosynthesis in action 2
... disease that can lead to life-threatening heart and digestive ... thought, according to research from The University of Texas ... years now, and this year the number of disease-causing ... integrative biology and philosophy at The University of Texas ...
... the most stressful thing that can happen to anybody. But ... of traumatic experiences. Most humans come to terms with it ... How weaning takes place, however, can have a dramatic effect on ... this is so, at least for horses, comes from the latest ...
... Over the next decade, the population of cancer survivors over ... "We can expect a dramatic increase in the ... a history of cancer," said Julia Rowland, Ph.D., director of ... Control and Population Sciences at the National Cancer Institute (NCI). ...
Cached Biology News:Chagas disease may be a threat in South Texas, says researcher 2The short goodbye: Weaning foals 2The short goodbye: Weaning foals 3Older cancer survivor population to increase substantially 2
(Date:7/10/2014)... (PRWEB) July 10, 2014 OMICS Group’s ... techniques during 18-20 August, 2014 at Double Tree by ... the recent developments in Analytical & Bioanalytical research methods ... , Speaking on this occasion, Dr. Srinubabu Gedela, MD ... Acta conference is a remarkable one in bringing a ...
(Date:7/10/2014)... Capital, a firm specializing in acquiring and managing food ... the Slim-Fast brand from Unilever. Unilever will retain a ... were not disclosed. Slim-Fast is a branded ... shakes, powders, bars and snacks to retail customers throughout ... United Kingdom and Ireland.  The ...
(Date:7/10/2014)... the fight against terrorism with the creation of a ... the use of light and special glass fibres. , ... Chemical , the researchers describe a novel optical fibre ... as 6.3 ppm (parts per million). It requires an ... explosives detection has involved looking for metals that encase ...
(Date:7/10/2014)... RICHLAND, Wash. The lithium-ion batteries that power our ... run longer on a single charge with the help ... the porous material to replace the graphite traditionally used ... more than 10 times the energy storage capacity of ... lithium-ion battery electrode was published today in Nature ...
Breaking Biology Technology:A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Kainos Capital Acquires Slim-Fast From Unilever 2Detecting trace amounts of explosives with light 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3
... few as 1 cell , Karen Dolter ... RNA microprep kit provides a,convenient method for isolating total ... is bound to a solid support, which eliminates the,need ... high quality, with no detectable DNA contamination and is ...
... higher transformation efficiency of ligated DNA , ... ,Stratagene Cloning Systems, Inc. , Stratagenes new, high-efficiency ... efficiency of ligated DNA. Epicurian,Coli ... for ligated DNA that were up to 25-fold ...
... Mycoplasma PCR Primer Set for fast and easy ... Arrington ,Yale University , D. R. Staggs ,Genetic Applications ... mammalian cell cultures can substantially,reduce the potency of transfection ... before the optimal amounts of LipoTAXI ...
Cached Biology Technology:Fast Isolation of Total RNA from Small Numbers of Cells 2Fast Isolation of Total RNA from Small Numbers of Cells 3Fast Isolation of Total RNA from Small Numbers of Cells 4Fast Isolation of Total RNA from Small Numbers of Cells 5Fast Isolation of Total RNA from Small Numbers of Cells 6New Competent Cells for Highest Transformation Efficiencies 2New Competent Cells for Highest Transformation Efficiencies 3New Competent Cells for Highest Transformation Efficiencies 4New Competent Cells for Highest Transformation Efficiencies 5New Competent Cells for Highest Transformation Efficiencies 6New Competent Cells for Highest Transformation Efficiencies 7New Competent Cells for Highest Transformation Efficiencies 8Mycoplasma Contamination Reduces the Effect of Lipid-Mediated Transfection,of Mammalian Cells 2Mycoplasma Contamination Reduces the Effect of Lipid-Mediated Transfection,of Mammalian Cells 3
... receptors constitute the principal excitatory ... classes of glutamate receptors exist: ... Ionotropic glutamate receptors are oligomeric ... NMDA1-3, KAI-2) which comprise ligand-gated ...
... Block Moto Alpha unit with motorized heated lid ... that is useful for microarrays and chips. The ... blocks. The sealing force of the motorized lid ... to give repeatable results. This interchangeable Moto Alpha ...
Caspr2 Antigen: Fusion protein amino acids 96-1265 (extracellular domain) of human Caspr2 Accession Number: NP_054860...
... N,N- bis- (3-D-Gluconamidopropyl)deoxycholamide ... of CHAPS and CHAPSO. Has reduced electrostatic ... exchange chromatography on DEAE-cellulose. Aggregation number: 8-16. ... in H 2 O. Aggregation number 8 ...
Biology Products: