Navigation Links
Chronix Biomedical's serum DNA assays monitor disease activity and treatment response in MS
Date:4/5/2010

San Jose, California, April 6, 2010 Chronix Biomedical today announced publication of a study that supports the utility of its serum DNA blood tests to predict clinical status and monitor disease activity and response to treatment in multiple sclerosis (MS). Chronix Biomedical uses proprietary technology to identify disease-specific genetic fingerprints based on the circulating DNA that is released into the bloodstream by damaged and dying cells. A growing body of publications from Chronix and other researchers shows that this circulating DNA can be identified and analyzed to provide a diagnostic window into ongoing changes in the genome associated with specific diseaseschanges that can be used to track the presence or absence of active disease. This new study is the first to show that the Chronix approach can be used to monitor the clinical status of a chronic disease. The findings are published in the current online edition of the Journal of Molecular Diagnostics.*

"These positive data further validate the premise underlying the Chronix approach, showing that the many genetic anomalies associated with active and stable relapsing-remitting MS can be detected by analyzing DNA fragments circulating in the blood serum," said Mario Clerici, M.D., Chair of Immunology, Department of Biomedical Sciences and Technologies, University of Milano, Milan, Italy and a co-author of the study. "The prognostic value achieved in this study supports the ability of this new approach to help manage relapsing-remitting multiple sclerosis, potentially offering clinicians a new tool to easily assess which MS treatment options are most effective for their patients, as well as providing critical information that will facilitate development of the next generation of MS therapeutics."

In the study, researchers applied advanced analytical techniques developed by Chronix to identify genomic DNA fingerprints in the bloodstream of 28 MS patients known to have r
'/>"/>

Contact: Barbara Lindheim
blindheim@biocompartners.com
917-355-9234
BioCom Partners
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study shows Chronix technology using serum DNA can identify early presence of disease
2. NIST issues human milk and blood serum SRMs for contaminant measurements
3. Syracuse University partners with Serum Institute of India to develop vaccines for children
4. NIH grants Phylonix Phase II SBIR to develop high-throughput in vivo zebrafish assays
5. Genetic Engineering & Biotechnology News reports on growing use of cell-based assays
6. Chemist monitors nanotechnologys environmental impact
7. Counting frogs: Why monitoring our amphibian populations is important
8. Boost ivory trade monitoring and enforcement before allowing one-off sales: UBC researcher
9. Fluorescence monitoring and effect of photodynamic therapy for port wine stains
10. Volcano monitoring will target hazard threat to Marianas, US military and commercial jets
11. ACS webinar features developments in online water and wastewater monitoring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... New Rochelle, NY, July 9, 2014Biofuels derived from the ... alternative to fossil fuels. To achieve this goal, optimization ... as in open pond systems, is needed. Sapphire Energy ... contamination of open pond algae cultivation systems, described in ... Ann Liebert, Inc., publishers. The article is available on ...
(Date:7/9/2014)... a University of Guelph scientist that involved fitting ... exposure to a neonicotinoid pesticide hampers bees, ability ... Nigel Raine, a professor in Guelph,s School of ... London was published July 9 in the British ... The study shows how long-term pesticide exposure affects ...
(Date:7/9/2014)... A new study shows that some shark species may be ... that may come with rising temperatures. , The Arctic today ... but it wasn,t always like that. Roughly 53 to 38 ... epoch, the Arctic was more similar to a huge temperate ... life, including ancestors of tapirs, hippo-like creatures, crocodiles and giant ...
Breaking Biology News(10 mins):Controlling contamination in open algae ponds for biofuels 2Bee foraging chronically impaired by pesticide exposure: Study 2Shark teeth analysis provides detailed new look at Arctic climate change 2Shark teeth analysis provides detailed new look at Arctic climate change 3
... researchers have identified the job of one of the ... puzzled scientists because it is present in nearly every ... and yet, in laboratory experiments, its function has remained ... enigmatic enzyme known as DinB DNA polymerase is specialized ...
... have identified a handful of microRNAs (miRNAs) that appear ... platelets ?blood cells critical to the body's ability to ... of these same miRNAs, when acting abnormally, may contribute ... that a specific set of miRNA genes are turned ...
... and slow developing gills appear to be keys to ... fish whose adults thrive in icy waters because of ... are important, researchers at the University of Illinois atUrbana-Champaign ... species of notothenioids that inhabit the Ross Sea at ...
Cached Biology News:Common enzyme is a key player in DNA repair 2Common enzyme is a key player in DNA repair 3MiRNA fingerprint identified in platelet formation 2Thin tough skin, slow-growing gills protect larval Antarctic fish 2Thin tough skin, slow-growing gills protect larval Antarctic fish 3
(Date:1/15/2014)... England , January 15, 2014 A ... win races on the Formula 1 track could help to ... McLaren Applied Technologies (MAT), Stowhealth (a GP surgery based in ... by healthcare provider Simplyhealth. Telemetry technology, which is ...
(Date:1/15/2014)... VA (PRWEB) January 15, 2014 Two ... have continued their sponsorship of an annual competition for ... in, and access to, innovative STEM study. The competition ... TEAMS: Tests of Engineering Aptitude, Mathematics, and Sciences ...
(Date:1/15/2014)... DTS Language Services, Inc . is pleased to ... Science organizations who need document translations. Clients will now ... documents in advance with a selection of nearly 50 life ... a critical factor in clinical and scientific fields, and decrease ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... throughput research solutions, today announced that Lupin Limited, one ... of Freeslate’s CM Protégé PharmD System for ... in Mumbai, India, is focused on a wide range ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5DTS Improves Efficiency for Life Science Document Translations 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3
... , Jan. 26 The following is a ... PharmAthene, regarding the Commission on the Prevention of Weapons of ... Card by the Commission on the Prevention of Weapons of ... America still remains vulnerable to bioterrorism.  Our Nation,s ability to ...
... , , TUALATIN, Ore. ... Bulletin Board: WYNX), a platform company dedicated to the ... announced that it has reached an agreement with British-based ... second generation Gas Quality Inferential Measurement Device (GasPT2). , ...
... Jan. 26 /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE ... that it may now enroll patients at US clinical sites ... lead product, nimotuzumab. One of the two trials is in ... treatment and being treated palliatively and the other in patients ...
Cached Biology Technology:Waytronx Announces Agreement for Development and Production of Its GASPT2 Device With UK-Based Ingenion Design Limited 2Waytronx Announces Agreement for Development and Production of Its GASPT2 Device With UK-Based Ingenion Design Limited 3Waytronx Announces Agreement for Development and Production of Its GASPT2 Device With UK-Based Ingenion Design Limited 4YM BioSciences announces FDA clearance for two ongoing Phase II nimotuzumab trials into USA 2YM BioSciences announces FDA clearance for two ongoing Phase II nimotuzumab trials into USA 3YM BioSciences announces FDA clearance for two ongoing Phase II nimotuzumab trials into USA 4YM BioSciences announces FDA clearance for two ongoing Phase II nimotuzumab trials into USA 5
Rabbit polyclonal to Aortic Elastin ( Abpromise for all tested applications). entrezGeneID: 2006 SwissProtID: P15502...
Rabbit polyclonal to GPR56 ( Abpromise for all tested applications). entrezGeneID: 9289 SwissProtID: Q9Y653...
Mouse monoclonal [2A4] to Cytokeratin 8 + 18 + 19 ( Abpromise for all tested applications). Antigen: Cytokeratins isolated from cultured pig kidney epithelial cells. Entrez GeneID: 3856 S...
Feline Rhinotracheitis Virus...
Biology Products: