Navigation Links
Chromosomal translocations point the way toward personalized cancer care
Date:8/13/2012

Sometimes even when we know a translocation is important, we might not be able to do anything about it," Wang says. "Sometimes these translocations might be present in healthy cells that we don't want to kill or some genes involved in translocations may be essential factors for cell survival. For example, we know that c-myc gene is upregulated in specific type of lymphomas but targeting c-myc gene will result in very high toxicity. Or in still other cases drugging the target can be more difficult than in others."

Today's challenge may be tomorrow's cure. Right now we're in the midst of a cancer care revolution toward personalized care based on a cancer's genetic signature and the study and exploitation of chromosomal translocations may lead the way.


'/>"/>

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Children exposed to the common pollutant naphthalene show signs of chromosomal damage
2. Tropical arks reach tipping point
3. Under the right conditions, peptide blocks HIV infection at multiple points along the way
4. Study points to causes of high dolphin deaths in Gulf of Mexico
5. Conatus Pharmaceuticals Appoints Mark F. Morris as Head of Biostatistics
6. Shrinking leaves point to climate change
7. 3-V Biosciences Appoints Douglas I. Buckley, PhD, as Vice President of Biology
8. Computer model pinpoints prime materials for efficient carbon capture
9. Its in the genes: Research pinpoints how plants know when to flower
10. Discovered a new checkpoint of cell cycle control through joint action of 2 proteins
11. Culturally sensitive research in United Arab Emirates pinpoints indoor air quality risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2015)... Mar. 19, 2015 Research and Markets ( ... Biometrics - Global Strategic Business Report" report to their ... Iris Biometrics in US$ Thousands. The report provides separate comprehensive ... Japan , Europe , ... and Latin America . Annual ...
(Date:3/17/2015)... , March 17, 2015 ... company specializing in clinical study management systems, is ... in attendance at ARENA,s Outsourcing in Clinical Trials ... This event provides an excellent forum for MedNet ... flexible and affordable software-as-a-service (SaaS) eClinical technology platform. ...
(Date:3/16/2015)... Between 16 and 20 ... innovations in biometric identification at the CeBIT exhibition ...      (Photo: http://photos.prnewswire.com/prnh/20150316/735333 ) , ... at the forefront: the company,s all new BiometricGate ... Germany . BiometricGate is the first ...
Breaking Biology News(10 mins):Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3
... hydrothermal ventsmore than a mile below the ocean ... stomach,they stand rooted to one spot. Fornourishment, they ... to metabolize the sulphurous volcanicsoup in which they ... these giantsare born bacteria-free, with a completedigestive system. ...
... In times of plenty, the uni-cellular slime mold Dictyostelium ... the forest floor. But these simple creatures can perform ... up, Dictyostelium amebas band together with their neighbors and ... , In a forthcoming study in Nature Chemical Biology, ...
... smoke during pregnancy can develop hearing-related cognitive deficits. For ... not only implicates nicotine as the culprit, but also ... cause these deficits. , In a study using ... and colleagues from UC Irvine, showed that nicotine exposure ...
Cached Biology News:Giant deep-sea tubeworm's meal ticket comes in as a skin infection 2Giant deep-sea tubeworm's meal ticket comes in as a skin infection 3When the going gets tough, slime molds start synthesizing 2When the going gets tough, slime molds start synthesizing 3When the going gets tough, slime molds start synthesizing 4Nicotine exposure during development leads to hearing problems 2Nicotine exposure during development leads to hearing problems 3
(Date:4/16/2015)...  AnaptysBio, Inc., a leader in the ... announced the advancement of its first-in-class anti-interleukin-36 ... The Company,s anti-IL-36R therapeutic antibody, called ANB019, ... psoriasis (GPP), an orphan systemic inflammatory disease ... owned within AnaptysBio,s proprietary antibody pipeline and ...
(Date:4/16/2015)... SAN DIEGO , April 16, 2015 ... company dedicated to improving cancer surgeries, announced today that ... lead fluorescent cancer illuminator, AVB-620, in women with primary, ... trial, the company also welcomed the addition of ... affairs. The open label, dose escalation study ...
(Date:4/16/2015)... Switzerland , April 16, ... part of Debiopharm Group ™ , a Swiss-based ... target unmet medical needs as well as ... on the investigational compounds Debio 1143 (SMAC mimetic) ... presented at the 2015 Annual meeting of ...
(Date:4/16/2015)... (PRWEB) April 16, 2015 Fairleigh ... Joseph V. Gulfo to become the Executive Director ... Simultaneously, FDU announced the kick-off of the Initiative ... spearheaded by Dr. Gulfo, under the Rothman Institute ... of Business) and in collaboration with FDU’s School ...
Breaking Biology Technology:AnaptysBio Advances First-In-Class Anti-IL-36 Receptor Antibody Program To Treat Orphan Inflammatory Disease 2Avelas Biosciences Initiates Phase 1b Trial of AVB-620 in Breast Cancer Patients 2Avelas Biosciences Initiates Phase 1b Trial of AVB-620 in Breast Cancer Patients 3Debiopharm International SA Announces Results of 2 Key Oncology Programs at 2015 AACR Conference 2Debiopharm International SA Announces Results of 2 Key Oncology Programs at 2015 AACR Conference 3Dr. Joseph V. Gulfo Named Executive Director of Fairleigh Dickinson University’s Rothman Institute to Spearhead New Initiative for Patient-Centered Innovation (iPCI) 2Dr. Joseph V. Gulfo Named Executive Director of Fairleigh Dickinson University’s Rothman Institute to Spearhead New Initiative for Patient-Centered Innovation (iPCI) 3
... K. Gwathmey VMD, Ph.D., FACC,FAHA has served as ... for twelve years. Gwathmey, Inc. is an internationally,recognized ... lead compounds prior to their conversion into marketable ... campaign with other members of the,quiet rural community ...
... MILWAUKEE, March 10 Elekta Neuromag(R), the,world-leading ... Magnetoencephalography (MEG) technology, has been ordered by,Froedtert ... ), Located in the western ... critical role in the quality of life ...
... The Netherlands, March 10 Two clinical,psychologists ... in,Holland, Jaap Hollander and Jeffrey Wijnberg, have ... is an online computer,program that helps people ... the,unique quality, as compared with other on ...
Cached Biology Technology:Elekta Chosen to Deliver Sophisticated Brain Mapping Technology to Froedtert Hospital in Milwaukee 2Elekta Chosen to Deliver Sophisticated Brain Mapping Technology to Froedtert Hospital in Milwaukee 3Robot Psychologist: A New Era in Mental Health Services With MindMentor 2
... polypeptide hormones which belong to the ... TGF- superfamily is a large group ... many aspects of development, reproductive function ... incude TGF-s, bone morphogenetic proteins, growth ...
... hormones which belong to the transforming ... superfamily is a large group of ... aspects of development, reproductive function and ... TGF-s, bone morphogenetic proteins, growth differentiation ...
... polypeptide hormones which belong to the ... TGF- superfamily is a large group ... many aspects of development, reproductive function ... incude TGF-s, bone morphogenetic proteins, growth ...
... EZ-Spread Plating Beads Sterile plating ... for glass rods and potentially hazardous ethanol flaming, ... Two choices of ready-to-use sterile packaging: dispenser bottle ... 50 plating, Fastest and easiest way ...
Biology Products: