Navigation Links
Chromosomal problems affect nearly all human embryos
Date:7/1/2009

Amsterdam, The Netherlands: For the first time, scientists have shown that chromosomal abnormalities are present in more than 90% of IVF embryos, even those produced by young, fertile couples. Ms Evelyne Vanneste, a PhD student in the Centre for Human Genetics and the University Fertility Center, Leuven University, Belgium, told the 25th annual conference of the European Society of Human Reproduction and Embryology today (Wednesday July 1), that the surprising finding meant that current techniques used in preimplantation genetic screening (PGS), where embryos are screened genetically in order to select the best embryo for transfer, do nothing to improve pregnancy and live birth rates. Indeed, it can lead to potentially viable embryos being discarded, she said.

Ms Vanneste and her team studied each cell from 23 three or four day-old IVF embryos from young (less than 35 years old), fertile couples who had asked for preimplantation genetic diagnosis (PGD). PGD is carried out where one or both parents have a known genetic abnormality, in this case an X-linked disorder or the microdeletions (loss of a tiny piece of a chromosome) that can cause such disorders as the cancer predisposition syndrome neurofibromatosis type 1. The embryos are screened to avoid the implantation of one carrying that abnormality. Such embryos are the most representative of normal human embryogenesis, the process that begins once an egg has been fertilised.

Using new technologies that can detect chromosomal aberrations in the whole genome (all human chromosomes) of a single cell, the team was able to screen embryonic cells at a much higher resolution than previously, and hence identify more chromosomal abnormalities than has been possible using the current technique, fluorescent in situ hybridisation (FISH), which can only analyse ten of the approximately 32,000 genetic regions at the same time.

"Until now, the majority of studies analysing the genetic compositi
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society for Human Reproduction and Embryology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New test can detect both genetic and chromosomal abnormalities in embryos
2. Physician-scientists seek solutions to reproductive problems related to chromosomal variations
3. Scientific evidence of health problems from past contamination of drinking water at Camp Lejeune is limited and unlikely to be resolved with further study
4. Queens researchers shine light on compact fluorescent bulb problems
5. Children who are dissatisfied with their appearance often have problems with their peer group
6. Duke forum to address global engineering problems
7. Maternal health problems in Myanmar widespread
8. MSU researcher studies ties between cholesterol drugs, muscle problems
9. Replacing the coach doesnt solve problems
10. Sounding out heart problems automatically
11. Can microorganisms be a solution to the worlds energy problems?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/2/2014)... , October 1, 2014 CARTES ... Major Trends in the Sector CARTES SECURE CONNEXIONS ... Centre from 4 to 6 November 2014. This 29 ... to payment, identification and mobility, will bring together the ... this year, a rich programme of conferences will set ...
(Date:10/1/2014)... , October 1, 2014 ... in the life science field  The ... come and go over the years. Some are ... Photon upconversion is a novel detection technology that ... years. Now, finally, this technology is becoming commercially ...
(Date:9/30/2014)... --- Do we think of nature as something that we ... need to "preserve?" Or do we think of ourselves as ... of nature, but what about a house? , The ... also reflected in our actions, our speech and in cultural ... the University of Washington, the American Indian Center of Chicago ...
Breaking Biology News(10 mins):CARTES SECURE CONNEXIONS - Conferences & Speakers 2014 2CARTES SECURE CONNEXIONS - Conferences & Speakers 2014 3CARTES SECURE CONNEXIONS - Conferences & Speakers 2014 4First-of-a-kind Solution for Utilizing Photon Upconversion 2The cultural side of science communication 2
... annual duck hunting season in the United States is traditionally big ... for decades, the number of hunters continues to fall. Far from ... Wildlife Society Bulletin shows how the loss of revenue from ... conservation work. "The last 15 years have brought hunting opportunities ...
... German . (Jena) On their mission to the moon ... the most famous footprints ever. Since the time the astronauts of ... their footprints remain almost unchanged. And as no breath of wind ... visible forever. Not quite so old but equally ,immortal, are ...
... NY, February 7, 2013 The Vilcek Foundation is pleased ... co-winners of the 2013 Vilcek Prize for Biomedical Science. Drs. ... Medicine and investigators with the Howard Hughes Medical Institute, were ... the innate immune system. "We are pleased ...
Cached Biology News:How a fall in duck hunting is shooting a financial hole into conservation efforts 2Waste dump at the end of the world 2Waste dump at the end of the world 3Vilcek Prize for Biomedical Science split between 2 giants of immunology 2Vilcek Prize for Biomedical Science split between 2 giants of immunology 3Vilcek Prize for Biomedical Science split between 2 giants of immunology 4
(Date:10/1/2014)... BETHESDA, Md. , Oct. 1, 2014 /PRNewswire/ ... committed to the fostering and monetization of intellectual ... Spherix,s litigation against VTech and Uniden in the ... Texas has been rescheduled ... scheduled for October 2, 2014.  The Court Order ...
(Date:10/1/2014)... Irvine, CA (PRWEB) September 30, 2014 ... for user-friendly, cost-effective tools to address sales, training ... PMG has developed innovative mobile applications to ... studies, outlining the agency’s latest customized mobile app ... http://www.studiopmg.com/work . , In partnership with Toyota, ...
(Date:10/1/2014)... The U.S. Department of Labor has ... Edwardsville as part of the Trade Adjustment Assistance Community ... co-administered by the Department of Labor and Department of ... Thomas E. Perez and Secretary of Education Arne Duncan ... grants to nearly 270 colleges across the country. ...
(Date:9/30/2014)... . , Electrical ... a new kind of building block for digital integrated ... be based on three-dimensional arrangements of nanometer-scale magnets instead ... semiconductor industry CMOS fabrication of silicon chips ... the University of Notre Dame are exploring "magnetic computing" ...
Breaking Biology Technology:Markman Hearing Date for VTech and Uniden Litigation Now Set for November 10, 2014 2Digital Agency Studio PMG Launches New Case Studies on Website 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 3U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 4A new dimension for integrated circuits: 3-D nanomagnetic logic 2A new dimension for integrated circuits: 3-D nanomagnetic logic 3
... Inc. ("Company") (OTCQB: SVFC.PK) announced today that the Company has ... of Thailand, http://www.StemCells21.com . Stem Cells 21 is ... the College of Anti-ageing Medicine and a member of ... Managing Director for the Stem Cells 21.  They have ...
... University of Southern California Marshall School of Business, ranked among ... Marshall School of Business Leadership Summit to be held ... at Los Angeles, newest landmark, the JW Marriot—just steps away ... A new dynamic format will keep interest high ...
... is Preeclampsia Awareness Month and to build awareness of ... period, thousands of families in 36 cities in the ... The Preeclampsia Foundation is holding the Promise ... help provide patient support and education, raise public awareness, ...
Cached Biology Technology:IntelliCell BioSciences Signs Technology Licensing Agreement with Stem Cells 21 Thailand 2USC Marshall School of Business 6th Annual Leadership Summit 2USC Marshall School of Business 6th Annual Leadership Summit 3Preeclampsia Awareness Month Marked By Promise Walks in 36 Cities 2Preeclampsia Awareness Month Marked By Promise Walks in 36 Cities 3
Lysozyme C (W-20)...
Request Info...
Abgene's ALTO-8 is the first automated decapper/capper for Abgene Twist-Lock tubes....
... X-Gal (5-bromo-4-chloro-3-indoyl-beta-D-galactopyranoside) is a ... identify recombinant plasmids. In ... and IPTG, lac ... blue, whereas recombinant colonies ...
Biology Products: