Navigation Links
Choose your love
Date:1/23/2014

To test whether female mate choice enhances the health and disease-resistance of offspring, either through immune resistance, tolerance to infection, or both, researchers led by Dustin Penn tested female house mice's preferences (Mus musculus) for particular males and then experimentally assigned each female to mate with either their preferred or their non-preferred male. They found that females that mated with their preferred male produced more offspring and were better able to cope with infection (from Salmonella, a common mouse pathogen) compared to offspring sired by non-preferred males. They were no better at controlling pathogen loads than offspring from non-preferred males, which suggests that the fitness benefits were due to tolerance to infection rather than immune resistance (the ability to control or eliminate pathogens) per se.

In 1982, Hamilton and Zuk suggested that mate choice enables females to select healthy, disease-resistant males, and produce disease-resistant offspring. Since then many studies have confirmed that showy secondary sexual traits provide information about males' immune resistance and parasite loads, and females are more attracted to healthy males. Doubts have remained about the hypothesis, however, partly because studies so far have mainly measured disease-resistance indirectly, assessing parasite loads or immune responses to antigens, which do not necessarily reflect health and disease-resistance.

This study provides direct experimental evidence that females' partner preferences enhance the ability of offspring to cope with infection in house mice. The authors suggest that females assess males' overall condition and health rather than immune resistance per se, and for this reason, sexual selection should enhance offspring tolerance, as well as immune resistance to infection. Penn and others have shown that ability to resist and survive Salmonella infection is influenced by MHC genes and other loci. However, he emphasizes that they still need to determine whether the fitness benefits they found were due to genetics or maternal allocation into preferred offspring, and that either mechanism will be interesting to explore in future studies.

Shirley Raveh, the lead author of the paper said she was "quite surprised by their findings. If there are indirect benefits from sexual selection, they would have been for improved immune resistance."

She explains that she hopes their findings will stimulate renewed interest in parasite-mediated sexual selection, along with the rapidly growing interest in tolerance to infection.


'/>"/>

Contact: Dustin Penn
dustin.penn@vetmeduni.ac.at
43-148-909-15823
University of Veterinary Medicine -- Vienna
Source:Eurekalert  

Related biology news :

1. Dominant deer hinds choose the best food
2. Stryker Chooses Wineman Technology for Medical Device Test Equipment and Software
3. South Africas Capitec Bank Chooses Diebold Cash Recycling ATMs
4. Friend or foe: Babies choose sides early
5. High-testosterone competitors more likely to choose red
6. Schools help kids choose carrots over candy bars
7. Boost careers of female scientists: Make sure women help choose meeting speakers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Choose your love
(Date:12/22/2016)... SuperCom (NASDAQ:   SPCB ... e-Government, Public Safety, HealthCare, and Finance sectors announced today that Leaders ... to implement and deploy a community-based supportive services program to reduce ... , further expanding its presence in the state. ... This new program, which is expected ...
(Date:12/16/2016)...   IdentyTechSolutions America LLC , a leading ... and a cutting-edge manufacturer of software and hardware ... seamless, integrated solutions that comprise IDT biometric readers ... provide IdentyTech,s customers with combined physical identification and ... and theft. "We are proud to ...
(Date:12/15/2016)... , Dec. 15, 2016   WaferGen Bio-systems, ... held genomics technology company, announced today that on December ... Qualifications Department of The Nasdaq Stock Market LLC which ... bid price of WaferGen,s common stock had been at ... WaferGen has regained compliance with Listing Rule 5550(a)(2) of ...
Breaking Biology News(10 mins):
(Date:1/17/2017)... , Jan. 17, 2017  Protagonist Therapeutics, Inc. ... it has initiated a global Phase 2b induction ... peptide that targets alpha4beta7 integrin. The aim of ... to evaluate the safety/tolerability and efficacy of PTG-100 ... moderate to severe active disease. ...
(Date:1/16/2017)... ... January 16, 2017 , ... Attagene , a Research ... U.S. Small Business Administration. The Tibbetts Award honors the Small Business Innovation ... and are considered the best of the best from the thousands of firms ...
(Date:1/13/2017)... -- Research and Markets has announced the addition of ... to 2021" report to their offering. ... The biosimilars market is expected to ... 2016, at a CAGR of 26.3%. The global ... and application. Factors such as rising incidence of various diseases, increasing ...
(Date:1/13/2017)... Island, NY (PRWEB) , ... January 13, 2017 ... ... teamed up with several companies to offer its customers three new solutions for ... probe would come in handy if a customer has an oddly-shaped sample that ...
Breaking Biology Technology: