Navigation Links
Choose your love
Date:1/23/2014

To test whether female mate choice enhances the health and disease-resistance of offspring, either through immune resistance, tolerance to infection, or both, researchers led by Dustin Penn tested female house mice's preferences (Mus musculus) for particular males and then experimentally assigned each female to mate with either their preferred or their non-preferred male. They found that females that mated with their preferred male produced more offspring and were better able to cope with infection (from Salmonella, a common mouse pathogen) compared to offspring sired by non-preferred males. They were no better at controlling pathogen loads than offspring from non-preferred males, which suggests that the fitness benefits were due to tolerance to infection rather than immune resistance (the ability to control or eliminate pathogens) per se.

In 1982, Hamilton and Zuk suggested that mate choice enables females to select healthy, disease-resistant males, and produce disease-resistant offspring. Since then many studies have confirmed that showy secondary sexual traits provide information about males' immune resistance and parasite loads, and females are more attracted to healthy males. Doubts have remained about the hypothesis, however, partly because studies so far have mainly measured disease-resistance indirectly, assessing parasite loads or immune responses to antigens, which do not necessarily reflect health and disease-resistance.

This study provides direct experimental evidence that females' partner preferences enhance the ability of offspring to cope with infection in house mice. The authors suggest that females assess males' overall condition and health rather than immune resistance per se, and for this reason, sexual selection should enhance offspring tolerance, as well as immune resistance to infection. Penn and others have shown that ability to resist and survive Salmonella infection is influenced by MHC genes and other loci. However, he emphasizes that they still need to determine whether the fitness benefits they found were due to genetics or maternal allocation into preferred offspring, and that either mechanism will be interesting to explore in future studies.

Shirley Raveh, the lead author of the paper said she was "quite surprised by their findings. If there are indirect benefits from sexual selection, they would have been for improved immune resistance."

She explains that she hopes their findings will stimulate renewed interest in parasite-mediated sexual selection, along with the rapidly growing interest in tolerance to infection.


'/>"/>

Contact: Dustin Penn
dustin.penn@vetmeduni.ac.at
43-148-909-15823
University of Veterinary Medicine -- Vienna
Source:Eurekalert  

Related biology news :

1. Dominant deer hinds choose the best food
2. Stryker Chooses Wineman Technology for Medical Device Test Equipment and Software
3. South Africas Capitec Bank Chooses Diebold Cash Recycling ATMs
4. Friend or foe: Babies choose sides early
5. High-testosterone competitors more likely to choose red
6. Schools help kids choose carrots over candy bars
7. Boost careers of female scientists: Make sure women help choose meeting speakers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Choose your love
(Date:4/3/2017)... , April 3, 2017  Data ... precision engineering platform, detected a statistically significant ... product prior to treatment and objective response ... the potential to predict whether cancer patients ... to treatment, as well as to improve ...
(Date:3/29/2017)... 2017  higi, the health IT company that operates ... America , today announced a Series B investment ... EveryMove. The new investment and acquisition accelerates higi,s strategy ... transform population health activities through the collection and workflow ... higi collects and secures data today on behalf of ...
(Date:3/24/2017)... DUBLIN , Mar 24, 2017 Research ... Vehicle Access System Market Analysis & Trends - Industry Forecast to ... ... poised to grow at a CAGR of around 15.1% over the ... This industry report analyzes the market estimates and forecasts for ...
Breaking Biology News(10 mins):
(Date:4/26/2017)... (PRWEB) , ... April 26, 2017 , ... ... be demonstrating its new Bioflash MailGuardtm mail security screening solution at the National ... The Bioflash MailGuard system provides a fast, highly accurate, easy to use and ...
(Date:4/25/2017)... ... , ... As part of the Stago EdVantage Virtual University Virtual ... in order to illuminate this clinical problem for people unfamiliar with the topic. , ... a high degree of morbidity and mortality. DIC is a confusing disorder from both ...
(Date:4/25/2017)... ... April 25, 2017 , ... ... & Rehabilitation, P.A. , proudly announced today that acclaimed physiatrist Matthew Terzella, MD, ... on May 15, 2017. , Dr. Terzella completed his residency in Physical Medicine ...
(Date:4/24/2017)... 24, 2017  Dante Labs announced today the offer of ... (ca. $900). While American individuals have been able to access ... can access WGS below EUR 1,000. The sequencing ... genetic information to make informed decisions about disease monitoring, prevention, ... ...
Breaking Biology Technology: