Navigation Links
Chloride increases response to pheromones and odors in mouse sensory neurons
Date:12/28/2009

The vomeronasal organ (VNO) is an odor detection system that mediates many pheromone-sensitive behaviors. Vomeronasal sensory neurons (VSNs), located in the VNO, are the initial site of interaction with odors and pheromones. How an individual VSN transduces chemical signals into electrical signals, however, has been a mystery. In the January 2010 issue of the Journal of General Physiology (www.jgp.org), researchers from the University of Vermont show that a Ca 2+ -activated chloride current contributes approximately 80% of the response to urine in mouse VSNs.

Using patch clamp recordings and whole cell recordings, the team found that that urine-induced inward current was decreased in the presence of chloride channel blockers. Furthermore, the urine-induced currents were eliminated when both extracellular Ca 2+ and Na + were removed. The team's overall findings show that chloride acts as a major amplifier for signal transduction in mouse VSNs, increasing the responsiveness to pheromones or odorants.


'/>"/>

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related biology news :

1. Chloride found at levels that can harm aquatic life in urban streams of the Northern US
2. Study finds Viagra increases release of key reproductive hormone
3. Springer increases publishing activities in South Korea
4. Age increases chance of success as two-timer
5. Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms
6. Waterborne carbon increases threat of environmental mercury
7. New study increases concerns about climate model reliability
8. Varying prevalence among ethnic groups of gene mutation that increases risk of breast cancer
9. Washington University increases fleet of Roche Genome Sequencer FLX Systems
10. Gene variant increases breast cancer risk
11. Ibuprofen or acetaminophen in long-term resistance training increases muscle mass/strength
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/16/2016)... SAN FRANCISCO , June 16, 2016 /PRNewswire/ ... Market size is expected to reach USD ... report by Grand View Research, Inc. Technological proliferation ... and banking applications are expected to drive the ... ) , The development of ...
(Date:6/3/2016)... 2016 Das DOTM ... Nepal hat ein 44 Millionen ... Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an ... und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale ... teilgenommen, aber Decatur wurde als konformste und ...
(Date:5/24/2016)... Ampronix facilitates superior patient care by providing unparalleled technology to leaders of the medical ... premium product recently added to the range of products distributed by Ampronix. ... ... ... Ampronix News ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... is pleased to announce the launch of their brand, UP4™ Probiotics, into Target ... over 35 years, is proud to add Target to its list of well-respected ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute approval ... of microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the ... at the Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application ... team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding our ...
(Date:6/23/2016)... NEW YORK , June 23, 2016 ... the trading session at 4,833.32, down 0.22%; the Dow Jones ... the S&P 500 closed at 2,085.45, down 0.17%. Stock-Callers.com has ... INFI ), Nektar Therapeutics (NASDAQ: NKTR ... BIND Therapeutics Inc. (NASDAQ: BIND ). Learn more ...
Breaking Biology Technology: