Navigation Links
Chitosan conduits combined with NGF microspheres repair facial nerve defects

The chitosan molecule can promote nerve cell adherence and growth along the surface of the material. It can enhance the adherence and influx of Schwann cells, thus encouraging the growth of axons. However, physical nerve guidance by a nerve conduit may not be sufficient to foster optimal recovery. Dr. Huawei Liu and colleagues from Institute of Stomatology, Chinese PLA General Hospital in China prepared microspheres containing nerve growth factor for sustained release by a compound method, and implanted them into chitosan conduits to repair 10-mm defects on the right buccal branches of the facial nerve in rabbits. Researchers found that the sustained in vitro release of active nerve growth factor lasted for at least 90 days. The muscular atrophy induced by facial nerve defects was attenuated, and the nerve conduction velocity and amplitude were significantly increased. Moreover, microspheres for sustained release of nerve growth factor in combination with chitosan conduits improved axon and myelin sheath regeneration of injured facial nerve. These findings, published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), indicate that the combination of nerve growth factor-releasing microspheres and chitosan conduits exhibits superior effects in repairing facial nerve injury compared with nerve growth factor alone.


Contact: Meng Zhao
Neural Regeneration Research

Page: 1

Related biology news :

1. Neural stem cell transplants for spinal cord injury maximized by combined, complimentary therapies
2. Combined pesticide exposure affects bumblebee colony success
3. Synthetic and biological nanoparticles combined to produce new metamaterials
4. Combined therapy could repair and prevent damage in Duchenne muscular dystrophy
5. Ingredient in turmeric spice when combined with anti-nausea drug kills cancer cells
6. Stem cells can repair a damaged cornea
7. Epigenetic signatures direct the repair potential of reprogrammed cells
8. New heart repair strategies discussed at UH lecture May 15
9. Heart Damage Repaired By Reprogramming Resident Fibroblasts into Functioning Heart Cells
10. Scientists tie DNA repair to key cell signaling network
11. Detector of DNA damage: Structure of a repair factor revealed
Post Your Comments:
Related Image:
Chitosan conduits combined with NGF microspheres repair facial nerve defects
(Date:6/21/2016)... Columbia , June 21, 2016 ... to the new role of principal product architect ... named the director of customer development. Both will ... chief technical officer. The moves reflect NuData,s strategic ... in response to high customer demand and customer ...
(Date:6/16/2016)... 2016 The global ... reach USD 1.83 billion by 2024, according to ... Technological proliferation and increasing demand in commercial buildings, ... drive the market growth.      (Logo: ... development of advanced multimodal techniques for biometric authentication ...
(Date:6/9/2016)... attendance control systems is proud to announce the introduction of fingerprint attendance control software, ... employees are actually signing in, and to even control the opening of doors. ... ... ... Photo - ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... June 24, 2016 Epic Sciences unveiled ... cancers susceptible to PARP inhibitors by targeting homologous ... (CTCs). The new test has already been incorporated ... multiple cancer types. Over 230 clinical ... response pathways, including PARP, ATM, ATR, DNA-PK and ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with experienced ... this eBook by providing practical tips, tools, and strategies for clinical researchers. , ...
(Date:6/23/2016)... /PRNewswire/ - FACIT has announced the creation of ... company, Propellon Therapeutics Inc. ("Propellon" or "the Company"), ... portfolio of first-in-class WDR5 inhibitors for the treatment ... represent an exciting class of therapies, possessing the ... cancer patients. Substantial advances have been achieved with ...
(Date:6/23/2016)... Lawrence, MA (PRWEB) , ... June 23, 2016 ... ... the Peel Plate® YM (Yeast and Mold) microbial test has received AOAC Research ... test platform of microbial tests introduced last year,” stated Bob Salter, Vice President ...
Breaking Biology Technology: