Navigation Links
Chitosan conduits combined with NGF microspheres repair facial nerve defects
Date:12/27/2013

The chitosan molecule can promote nerve cell adherence and growth along the surface of the material. It can enhance the adherence and influx of Schwann cells, thus encouraging the growth of axons. However, physical nerve guidance by a nerve conduit may not be sufficient to foster optimal recovery. Dr. Huawei Liu and colleagues from Institute of Stomatology, Chinese PLA General Hospital in China prepared microspheres containing nerve growth factor for sustained release by a compound method, and implanted them into chitosan conduits to repair 10-mm defects on the right buccal branches of the facial nerve in rabbits. Researchers found that the sustained in vitro release of active nerve growth factor lasted for at least 90 days. The muscular atrophy induced by facial nerve defects was attenuated, and the nerve conduction velocity and amplitude were significantly increased. Moreover, microspheres for sustained release of nerve growth factor in combination with chitosan conduits improved axon and myelin sheath regeneration of injured facial nerve. These findings, published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), indicate that the combination of nerve growth factor-releasing microspheres and chitosan conduits exhibits superior effects in repairing facial nerve injury compared with nerve growth factor alone.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. Neural stem cell transplants for spinal cord injury maximized by combined, complimentary therapies
2. Combined pesticide exposure affects bumblebee colony success
3. Synthetic and biological nanoparticles combined to produce new metamaterials
4. Combined therapy could repair and prevent damage in Duchenne muscular dystrophy
5. Ingredient in turmeric spice when combined with anti-nausea drug kills cancer cells
6. Stem cells can repair a damaged cornea
7. Epigenetic signatures direct the repair potential of reprogrammed cells
8. New heart repair strategies discussed at UH lecture May 15
9. Heart Damage Repaired By Reprogramming Resident Fibroblasts into Functioning Heart Cells
10. Scientists tie DNA repair to key cell signaling network
11. Detector of DNA damage: Structure of a repair factor revealed
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chitosan conduits combined with NGF microspheres repair facial nerve defects
(Date:3/30/2017)... , March 30, 2017  On April 6-7, 2017, ... the Genome hackathon at Microsoft,s headquarters in ... competition will focus on developing health and wellness apps ... Hack the Genome is the first hackathon ... The world,s largest companies in the genomics, tech and ...
(Date:3/27/2017)... 2017  Catholic Health Services (CHS) has been ... (HIMSS) Analytics for achieving Stage 6 on the ... In addition, CHS previously earned a place in ... electronic medical record (EMR). "HIMSS Analytics ... EMR usage in an outpatient setting.  This recognition ...
(Date:3/22/2017)...   Neurotechnology , a provider of high-precision ... the release of the SentiVeillance 6.0 ... recognition using up to 10 surveillance, security and ... new version uses deep neural-network-based facial detection and ... a Graphing Processing Unit (GPU) for enhanced speed. ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... , ... August 15, 2017 , ... ... the largest Asian exhibitions for analytical and scientific instruments. This year’s symposium, organized ... “New Approaches in Mass Spectrometry for Bioanalytical Applications.” This dynamic presentation will discuss ...
(Date:8/15/2017)... Allentown, PA (PRWEB) , ... August 15, 2017 ... ... and encrypted shopping cart. Now mobile responsive, the new website makes it ... lab or anywhere in between. Users can now find detailed product information, educational ...
(Date:8/11/2017)... (PRWEB) , ... August 11, 2017 , ... A staple ... campaign this month that will incorporate important key elements including a new digital marketing ... community that has supported them, Bill Miller has partnered with the South Texas Blood ...
(Date:8/10/2017)... Yorba Linda, Ca (PRWEB) , ... August 09, ... ... and exosomes for regenerative medicine applications in the clinic is here. The team ... secreted EVs present in conditioned medium for clinical studies. , Dr. Travis ...
Breaking Biology Technology: