Navigation Links
Chip checks for oral cancer
Date:4/5/2010

currently available that work in a reliable way."

He said patients with suspicious lesions, usually discovered by dentists or oral surgeons, end up getting scalpel or punch biopsies as often as every six months. "People trained in this area don't have any trouble finding lesions," McDevitt said. "The issue is the next step -- taking a chunk of someone's cheek. The heart of this paper is developing a more humane and less painful way to do that diagnosis, and our technique has shown remarkable success in early trials."

The way forward is with nano-bio-chips -- small, semiconductor-based devices that combine the ability to capture, stain and analyze biomarkers for a variety of health woes that also include cardiac disease, HIV and trauma injuries. Researchers hope the eventual deployment of nano-bio-chips will dramatically cut the cost of medical diagnostics and contribute significantly to the task of bringing quality health care to the world.

The new study compared results of traditional diagnostic tests with those obtained with nano-bio-chips on a small sample of 52 participants, all of whom had visible oral lesions, leukoplakia or erythroplakia and had been referred to specialists for surgical biopsies or removal of the lesions. Of those patients, 11 were diagnosed as healthy.

The chips should also be able to see when an abnormality turns precancerous. "You want to catch it early on, as it's transforming from pre-cancer to the earliest stages of cancer, and get it in stage one. Then the five-year survival rate is very high," he said. "Currently, most of the time, it's captured in stage three, when the survivability is very low."

The device is on the verge of entering a more extensive trial that will involve 500 patients in Houston, San Antonio and England. That could lead to an application for FDA approval in two to four years.

Eventually, McDevitt said, dentists may be the first line of defense against oral c
'/>"/>

Contact: David Ruth
druth@rice.edu
713-348-6327
Rice University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Energy-saving method checks refrigerant level in air conditioners
2. New discovery is a significant boost to cancer research
3. VARI study could improve treatments for prostate cancer
4. New cancer therapy may fight cardiovascular disease
5. Cancer therapy using unique imaging, delivery system focus of NSF CAREER Award
6. Advances reported in quest for drugs targeting childhood cancer
7. Development of new anti-cancer gene therapy approach using lentiviral vectors
8. Specific lymph node radiotherapy is well-tolerated after surgery in early breast cancer patients
9. New way discovered to predict which breast cancer patients should be treated with anthracyclines
10. Vaccine could delay bowel inflammation and colon cancer, says Pitt research
11. IU researchers target vascular disease linked to cancer-causing gene mutation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... University researchers are using magnetic beads and DNA "springs" ... used as microscale models for polymer macromolecules. , The ... theory in the 1950s, can be made as stiff ... interest to materials scientists who study the basic physics ... and biomolecular engineer Sibani Lisa Biswal and graduate student ...
(Date:7/28/2014)... help advance the genetic engineering of "fuel" crops ... developed by researchers with the U.S. Department of ... partnership led by Lawrence Berkeley National Laboratory (Berkeley ... that enables scientists to identify and characterize the ... the biosynthesis of plant cell walls. , "Our ...
(Date:7/28/2014)... killers to prevent and treat HIV infection has been ... these molecules can arouse as they get rid of ... the Weizmann Institute and the National Institutes of Health ... molecules interferons around the time of infection ... disease. Their research appeared in Nature . ...
Breaking Biology News(10 mins):Seeing is bead-lieving 2How sweet it is 2How sweet it is 3Interfering with interferon 2
... has identified a genetic variant that substantially increases the ... populations. The study, published by Cell Press on August ... , associates a deletion on chromosome 3 with increased ... that affects 1% of the world population. Characterized by ...
... scientists have been able to measure the amount of water that ... result -- 285 billion metric tons, or 285 cubic kilometers of ... over half the volume of Lake Erie, which is the world,s ... of the water flowing through the Amazon River every year, and ...
... Swine Flu. Rabies. These are emerging infectious diseases where ... another and now infect humans. This is a phenomenon ... to determine what drives it. Gary McCracken, a ... head in Ecology and Evolutionary Biology, is one of ...
Cached Biology News:Large risk schizophrenia marker revealed 2First satellite measurement of water volume in Amazon floodplain 2First satellite measurement of water volume in Amazon floodplain 3UT professor uncovers clues into how viruses jump from hosts 2
(Date:7/28/2014)... The National Model Aviation Museum, located at ... to announce that it has been granted full civilian ... States Air Force. , The certification is the culmination ... spring with an on-site inspection by Sarah Sessions, Museum ... National Museum of the United States Air Force ...
(Date:7/25/2014)... study by researchers from the University of Leicester ... function, unlocking the potential to create new materials ... has been published in the prestigious academic journal ... laser technique to examine in rich detail the ... cluster containing an acetylene molecule and a single ...
(Date:7/25/2014)... California (PRWEB) July 25, 2014 Lawrence ... named to Thomson Reuters list of " The World's ... are part of the 3,000 researchers who were identified ... to recognize those who published the highest-impact work (2002-2012 ... research papers on combustion modeling . , "This ...
(Date:7/24/2014)... -- Keryx Biopharmaceuticals, Inc. (Nasdaq:KERX) (the "Company") announced the ... Phase 3 study of Zerenex (ferric citrate), the Company,s ... of hyperphosphatemia in patients with end-stage renal disease (ESRD) ... delivery with FErric CiTrate in EsrD) was published online ... of Nephrology ( JASN ). , ...
Breaking Biology Technology:AMA’s National Model Aviation Museum Granted Full Civilian Museum Certification by the National Museum of the United States Air Force 2Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster 2Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster 3Scientists Burst onto Influential List for Combustion Research 2Scientists Burst onto Influential List for Combustion Research 3Scientists Burst onto Influential List for Combustion Research 4Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 2Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 3Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 4
... Senior clinical executives from top ... met recently at the US offices of Shire ... for a global competition to recognise and encourage ... The US Clinical Researcher of the Year ...
... disease, brain neurons become clogged with tangled proteins. ... malfunctions in a little-known regulatory system within cells. ... about this particular regulatory system in mice. Such ... other diseases in humans and could eventually provide ...
... 16, 2012 Cord Blood America, Inc . ( ... umbilical cord blood stem cell preservation company focused ... families nationwide and internationally, today announced that revenues for 2011 ... in 2010.  The Company announced a gross profit increase in ...
Cached Biology Technology:Quality Standards Established for Competition to Identify Best Researchers in the US 2Study dusts sugar coating off little-known regulation in cells 2Study dusts sugar coating off little-known regulation in cells 3Study dusts sugar coating off little-known regulation in cells 4Cord Blood America Revenues Up 37 Percent to $5.67 Million in 2011 2
Human beta IG-H3 MAb (Clone 348506) Keywords: BIGH3, betaIG-H3 Protein Family: Extracellular Matrix Molecules...
Human Siglec-9 Biotinylated Affinity Purified Pab...
... an inhibitor of caspase-3/7 ... of inhibitor required to ... be determined empirically for ... inhibitor is sufficient to ...
Human RELT/TNFRSF19L MAb (Clone 238104)...
Biology Products: