Navigation Links
Chinese scientists discover marker indicating the developmental potential of stem cells
Date:4/16/2010

s rate of obtaining iPS cells with full pluripotency was still extremely low, which significantly hindered the application of iPS cells in therapeutics and other aspects," Zhou said.

Believing that there might be some intrinsic gene expression difference between the lines of iPS cells with varying levels of pluripotency that could be identified at early culture stages, so that less viable lines could be abandoned and more viable lines focused on, Zhou teamed up with bioinformatics specialist Xiu-Jie Wang, who works at the Chinese academy's Institute of Genetics and Developmental Biology.

Together, their groups profiled the small RNA expression patterns of ES and iPS cell lines from different genetic backgrounds and with different pluripotent levels using Solexa technology.

"There are nearly 50 miRNAs encoded in this region, and those expressed miRNAs all exhibited consistent and significant expression differences between stem-cell lines with different pluripotency levels," Wang said. "With this discovery, iPS cells with different pluripotency can be distinguished in their early phases, which will, thus, significantly improve the production of full pluripotent iPS cells and promote their application in disease therapy," Wang said.

As stem cells can be applied in the treatment of many diseases related to tissue replacement or organ implantation, Zhou said, if the team's findings also are true for humans, "it will cause a revolution in stem-cell research and the application of it in the very near future."


'/>"/>

Contact: Angela Hopp
ahopp@asbmb.org
301-634-7389
American Society for Biochemistry and Molecular Biology
Source:Eurekalert  

Page: 1 2

Related biology news :

1. UC-Riverside partners with Chinese university to address Chinas environmental problems
2. Dartmouth researchers alarmed by levels of mercury and arsenic in Chinese freshwater ecosystem
3. 2008 Pew Fellowship in Marine Conservation awarded to Fan Meng; first Chinese fellow
4. USP Convention and Chinese Pharmacopoeia Commission sign Memorandum of Understanding
5. Relocation of endangered Chinese turtle may save species
6. Study finds Chinese food good for your heart
7. Male crickets with bigger heads are better fighters, study reveals, echoing ancient Chinese text
8. Chinese slimming capsules
9. Reintroduced Chinese alligators now multiplying in the wild in China
10. Scientists help explain effects of ancient Chinese herbal formulas on heart health
11. Chinese medicine societies reject tiger bones ahead of CITES conference
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chinese scientists discover marker indicating the developmental potential of stem cells
(Date:12/17/2014)... N.C. , Dec. 16, 2014 Valencell, a ... its PerformTek biometric technology to industry leaders such as ... accurate, clinically validated, biometric wearable products. These products will ... in Las Vegas . ...
(Date:12/11/2014)... Markets , http://photos.prnewswire.com/prnh/20130307/600769 ... addition of the "Biometrics Market in India 2015-2019" ... major trend emerging in this market is the adoption ... than one characteristic of an individual for verification and ...
(Date:12/10/2014)... , Dec. 9, 2014  Wake Forest Baptist Medical Center today ... School of Medicine. Funding for this $50 million capital project ... publicly launched next summer. The medical education ... Reynolds Tobacco Company complex, adjacent to 525@vine in Wake Forest ...
Breaking Biology News(10 mins):Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4
... School Team 1 won the Colorado High School Science Bowl ... Bowl in Washington D.C., Apr. 25-29, where they will compete ... 70 high schools. The U.S. Department of Energy (DOE) ... to encourage high school students to explore math and science. ...
... second trimester markers for Down,s syndrome that are detected by ... Ultrasound in Obstetrics & Gynecology , the study,s results ... with the condition. Screening for Down,s syndrome is offered ... risk based on their age. Certain features detected during a ...
... when females choose to mate with more than one ... a team of scientists from Queen Mary, University of London, ... active role in selecting their mates, with a consistent proportion ... males each year. "Until now there has been ...
Cached Biology News:Study reveals significance of second trimester markers for Down's syndrome 2Female deer take control during the mating season 2
(Date:12/24/2014)...   BioLife Solutions , Inc. (NASDAQ: BLFS ), ... hypothermic storage and cryopreservation freeze media ... tissues  ("BioLife" or the "Company"), today announced that it will ... 2015 (the "Annual Meeting"). Because the expected date ...
(Date:12/24/2014)... 23, 2014 Earlier this year in a ... of the Adult Stem Cell Technology Center, LLC ( ASCTC ... unique property of adult tissue stem cells. His title ... Important for the Future,” embodied the essence of his message ...
(Date:12/24/2014)... According to Ross Selinger, President of Selinger ... the national office market continues to be strong, driven by ... by the third quarter’s surprising 3.9% GDP, unemployment decreasing to ... have held inflation down and the Fed is keeping interest ...
(Date:12/24/2014)... expects global cell isolation and expansion market to grow at ... about the vital drivers, restraints, trends, opportunities, strategies and challenges ... http://bit.ly/1yUxy0T , According to the report, the global market ... CAGR during near future. It expects this growth to be ...
Breaking Biology Technology:BioLife Solutions Sets Date for Annual Meeting of Stockholders 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3
... reporting system for studying NFAT activation , ... Chao-Feng Zheng ,Stratagene , Stratagenes new PathDetect ... designed for studying the activation of the,nuclear factor ... which play an essential role in inducible gene ...
... of your choice , , ... Inc. , The PathDetect in vivo signal ... the in vivo activation of signal transduction,pathways. ... fusion trans-activator,plasmid that expresses pathway-specific trans-activator proteins ...
... Mycoplasma PCR Primer Set for fast and easy detection ... ,Yale University , D. R. Staggs ,Genetic Applications LLC ... cell cultures can substantially,reduce the potency of transfection reagents. ... the optimal amounts of LipoTAXI ...
Cached Biology Technology:Cis-Reporting System Monitors Intracellular Calcium Mobilization 2Cis-Reporting System Monitors Intracellular Calcium Mobilization 3Cis-Reporting System Monitors Intracellular Calcium Mobilization 4Cis-Reporting System Monitors Intracellular Calcium Mobilization 5New Fusion Trans-Activator Plasmids for Studying Signal Transduction,Pathways 2New Fusion Trans-Activator Plasmids for Studying Signal Transduction,Pathways 3New Fusion Trans-Activator Plasmids for Studying Signal Transduction,Pathways 4New Fusion Trans-Activator Plasmids for Studying Signal Transduction,Pathways 5New Fusion Trans-Activator Plasmids for Studying Signal Transduction,Pathways 6Mycoplasma Contamination Reduces the Effect of Lipid-Mediated Transfection,of Mammalian Cells 2Mycoplasma Contamination Reduces the Effect of Lipid-Mediated Transfection,of Mammalian Cells 3
... Agarose-HR High Resolution - ... from 50 to 1000 ... for sizing PCR fragments, ... by restriction enzyme digestion, ...
... Immunogen: Synthetic peptide derived from ... mouse and rat LRP5. ... mouse LRP5 proteins. Reactivity: ... LRP5-pSEC-tag-transfected 293T cells MCF-7 T47D ...
Replacement Parts for Electrophoresis Apparatus...
...
Biology Products: