Navigation Links
Chinese herbal medicine may provide novel treatment for alcohol abuse
Date:1/5/2012

FINDINGS:

UCLA researchers have identified how a component of an ancient Chinese herbal anti-hangover medicine called dihydromyricetin, isolated from the plant Hovenia, counteracts acute alcohol intoxication and withdrawal symptoms.

The research team found that dihydromyricetin blocks the action of alcohol on the brain and neurons and also reduces voluntary alcohol consumption, with no major side effects, in an early study with rats. Specifically, dihydromyricetin inhibited alcohol's effect on the brain's GABAA receptors, specific sites targeted by chemicals from brain cells. Alcohol normally enhances the GABAA receptors' influence in slowing brain cell activity, reducing the ability to communicate and increasing sleepiness common symptoms of drunkenness.

The next stage of the research will involve human clinical trials, the researchers said.

IMPACT:

The research team determined that dihydromyricetin may provide a molecular target and cellular mechanism to counteract alcohol intoxication and dependence, leading to new therapeutic treatments all based on an ancient "folk medicine" treatment that has been used by humans for at least 500 years.

Alcohol use disorders are the most common form of substance abuse, affecting more than 76 million people worldwide, according to the World Health Organization. Only an estimated 13 percent of people identified as having an alcohol use disorder receive medical treatment, partly due to a lack of effective medications without major side effects. Although alcohol impacts most organ systems, its effect on the brain in developing intoxicating, sedative and addictive properties is critical.


'/>"/>
Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles Health Sciences
Source:Eurekalert

Page: 1

Related biology news :

1. Chinese scientists announce the first complete sequencing of Mongolian genome
2. Journal of the Chinese Chemical Society expands international reach with Wiley-VCH
3. 21st century database of traditional Chinese medicine released
4. Chinese researchers identify insect host species of a famous Tibetan medicinal fungus
5. BGI and National Wolfberry Engineering Research Center launch Chinese wolfberry genome project
6. John Innes Centre announces collaboration with Chinese Academy of Sciences
7. New SpringerOpen journal from the Chinese Academy of Sciences
8. Selected journals in Springers Chinese Library of Science join SpringerOpen
9. Most panda habitat is outside nature reserves according to joint MSU-Chinese research
10. Chinese-German collaboration yields new species of Large Blue butterfly
11. Revealing the ancient Chinese secret of sticky rice mortar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology: