The development of sequencing and bioinformatics tools to generate high throughput gene expression data and analysis has enabled such a large-scale fish transcriptome study. The project is extending an invitation to researchers worldwide to submit proposals and contribute fish specimens for sequencing. Scientists addressing questions about fishes with unique adaptations, economic, and medical value are particularly welcome to join the project.
Dr. Byrappa Venkatesh (Institute of Molecular and Cell Biology, Singapore), a member of the steering committee, said, "This project aims to generate unprecedented resources that would be valuable for improving our understanding of the evolution, adaptation and physiology of fishes, and designing strategies for the conservation and improvement of fish stock."
These resources will facilitate phylogenetic analysis of gene expression across a vast diversity of forms, "a powerful tool to identify genes that experienced evolutionary shifts in expression that are correlated with changes resulting in adaptive traits," said George Washington University Professor Guillermo Ort (another T1K steering committee member), "revealing genetic mechanisms underlying the origin of particular phenotypes."
|Contact: Jia Liu|