Navigation Links
Children's Hospital of Philadelphia receives federal grant to improve health care decision-making
Date:1/14/2013

The Children's Hospital of Philadelphia (CHOP) was awarded nearly $2M in research funding from the Patient-Centered Outcomes Research Institute (PCORI) to study antibiotic delivery to children returning home after hospitalization for a severe bacterial infection.

The CHOP research is one of 25 projects totaling $40.7M selected from a pool of 500 applicants by PCORI's Board of Governors following a competitive, multi-stage review process involving scientists, patients, caregivers and other stakeholders. Proposals were evaluated on the basis of scientific merit, engagement of patients and stakeholders, methodological rigor and fit within PCORI's National Priorities for Research and Research Agenda.

When a child hospitalized with a serious bacterial infection is discharged, clinicians have two options: (1) transition from the intravenous antibiotics used in the hospital to a prolonged course of oral antibiotics at home; or (2) insert a central venous catheter (PICC) into a large vein in the chest and train the parents in care of the PICC and administration of intravenous antibiotics at home. "These two antibiotic treatment options have major implications for the overall experience of the child, families and caregivers, but there is a lack of real-world evidence on their benefits and drawbacks to help clinicians and patient families make an informed choice," said Ron Keren, MD, MPH, who is leading the study and also directs the Center for Pediatric Clinical Effectiveness (CPCE) at CHOP. "If we find that the prolonged IV option is no better than the oral route, we think that most families would prefer for their child to take oral antibiotics."

In addition to studying the risks and benefits to each treatment choice, the research team will also include parent-investigators, who will inform the research questions being asked and advise the team on how best to communicate the pros and cons of each treatment option to parents.

"The announcement of funding for studies like this one mark a major milestone in our work as we build a portfolio of comparative clinical effectiveness research that will provide patients and those who care for them better information about the health care decisions they face," said PCORI Executive Director Joe Selby, MD, MPH. "These research projects reflect PCORI's patient-centered research agenda, emphasizing the inclusion of patients and caregivers at all stages of the research."


'/>"/>

Contact: Dana Mortensen
mortensen@email.chop.edu
267-426-6092
Children's Hospital of Philadelphia
Source:Eurekalert

Related biology news :

1. Hydrogen peroxide vapor enhances hospital disinfection of superbugs
2. Worries about dementia how hospitalization affects the elderly
3. Rhode Island Hospital: Adult entertainment workers likely to benefit from health care intervention
4. RI Hospital: Use of PMP may increase demand for drug treatment, reduce painkiller abuse
5. BGI and the Childrens Hospital of Philadelphia launch the 1,000 Rare Diseases Project
6. How alert hospital employees improved hospitals MSRA infection rate
7. $500,000 Gruber Foundation Genetics Prize goes to Philadelphia scientist
8. Bloomberg School receives $28 million for family planning advocacy
9. UC Riverside turfgrass specialist receives high honor
10. University of Illinois receives grant to study ozone resistance in corn
11. CU-led team receives $9.2 million DOE grant to engineer E. coli into biofuels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... Research and Markets has announced the addition of the ... ... grow at a CAGR of 30.37% during the period 2017-2021. ... prepared based on an in-depth market analysis with inputs from industry ... over the coming years. The report also includes a discussion of ...
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
(Date:4/3/2017)... , April 3, 2017  Data captured ... engineering platform, detected a statistically significant association ... prior to treatment and objective response of ... potential to predict whether cancer patients will ... treatment, as well as to improve both pre-infusion ...
Breaking Biology News(10 mins):
(Date:7/17/2017)... ... July 17, 2017 , ... Neurodevelopmental disorders ... range of overlapping clinical features. The advancement of targeted next-generation sequencing (NGS) has ... research and testing. , However, designing a custom panel for disease research ...
(Date:7/17/2017)... , ... July 17, 2017 , ... ... company that has developed and intends both to manufacture and sell reagents used ... the NASDAQ Capital Market. , Headquartered in Sandy, Utah, Co-Diagnostics’ intellectual property and ...
(Date:7/16/2017)... ... July 16, 2017 , ... OHAUS Corporation, a leading worldwide ... its new line of Rocking and Waving Shakers today. , Five New Models ... and digital) for laboratory applications in a variety of environmental conditions. Rocking shakers ...
(Date:7/15/2017)... ... July 15, 2017 , ... Cuvette manufacturer FireflySci has ... this time, the people at FFS have learned that their biggest asset was their ... are able to launch new products to meet the changing needs of scientists at ...
Breaking Biology Technology: