Navigation Links
Children's Hospital of Philadelphia receives federal grant to improve health care decision-making
Date:1/14/2013

The Children's Hospital of Philadelphia (CHOP) was awarded nearly $2M in research funding from the Patient-Centered Outcomes Research Institute (PCORI) to study antibiotic delivery to children returning home after hospitalization for a severe bacterial infection.

The CHOP research is one of 25 projects totaling $40.7M selected from a pool of 500 applicants by PCORI's Board of Governors following a competitive, multi-stage review process involving scientists, patients, caregivers and other stakeholders. Proposals were evaluated on the basis of scientific merit, engagement of patients and stakeholders, methodological rigor and fit within PCORI's National Priorities for Research and Research Agenda.

When a child hospitalized with a serious bacterial infection is discharged, clinicians have two options: (1) transition from the intravenous antibiotics used in the hospital to a prolonged course of oral antibiotics at home; or (2) insert a central venous catheter (PICC) into a large vein in the chest and train the parents in care of the PICC and administration of intravenous antibiotics at home. "These two antibiotic treatment options have major implications for the overall experience of the child, families and caregivers, but there is a lack of real-world evidence on their benefits and drawbacks to help clinicians and patient families make an informed choice," said Ron Keren, MD, MPH, who is leading the study and also directs the Center for Pediatric Clinical Effectiveness (CPCE) at CHOP. "If we find that the prolonged IV option is no better than the oral route, we think that most families would prefer for their child to take oral antibiotics."

In addition to studying the risks and benefits to each treatment choice, the research team will also include parent-investigators, who will inform the research questions being asked and advise the team on how best to communicate the pros and cons of each treatment option to parents.

"The announcement of funding for studies like this one mark a major milestone in our work as we build a portfolio of comparative clinical effectiveness research that will provide patients and those who care for them better information about the health care decisions they face," said PCORI Executive Director Joe Selby, MD, MPH. "These research projects reflect PCORI's patient-centered research agenda, emphasizing the inclusion of patients and caregivers at all stages of the research."


'/>"/>

Contact: Dana Mortensen
mortensen@email.chop.edu
267-426-6092
Children's Hospital of Philadelphia
Source:Eurekalert

Related biology news :

1. Hydrogen peroxide vapor enhances hospital disinfection of superbugs
2. Worries about dementia how hospitalization affects the elderly
3. Rhode Island Hospital: Adult entertainment workers likely to benefit from health care intervention
4. RI Hospital: Use of PMP may increase demand for drug treatment, reduce painkiller abuse
5. BGI and the Childrens Hospital of Philadelphia launch the 1,000 Rare Diseases Project
6. How alert hospital employees improved hospitals MSRA infection rate
7. $500,000 Gruber Foundation Genetics Prize goes to Philadelphia scientist
8. Bloomberg School receives $28 million for family planning advocacy
9. UC Riverside turfgrass specialist receives high honor
10. University of Illinois receives grant to study ozone resistance in corn
11. CU-led team receives $9.2 million DOE grant to engineer E. coli into biofuels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... March 21, 2017 Vigilant Solutions , ... law enforcement agencies, announced today the appointment of retired ... of public safety business development. Mr. Sheridan ... experience, including a focus on the aviation transportation sector, ... recent position, Mr. Sheridan served as the Aviation Liaison ...
(Date:3/9/2017)... Australia , March 9, 2017 /PRNewswire/ ... at the prestigious World Lung Imaging Workshop at the ... Fouras , was invited to deliver the latest data ... This globally recognised event brings together leaders at the ... latest developments in lung imaging. "The ...
(Date:3/2/2017)... -- Summary This report provides all the information ... and activities since 2010. ... Read the full report: http://www.reportlinker.com/p03605615-summary/view-report.html ... provides an in-depth insight into the partnering activity of one ... demand company reports are prepared upon purchase to ensure inclusion ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... 27, 2017  The global market for clinical ... to a new report from Kalorama Information.  In ... performed to evaluate disease progression, monitor drug treatment ... reasons.  The healthcare market research firm,s report, ... an overview of the medical laboratory industry and ...
(Date:3/27/2017)... March 27, 2017  Trovagene, Inc. (NASDAQ: TROV), a ... Executive Officer, Bill Welch , will be presenting ... at 9:00 AM EDT at the Essex House in ... and Chief Scientific Officer, Mark Erlander , Ph.D., ... the conference.   The presentation will be webcast ...
(Date:3/24/2017)... Research and Markets has announced the addition ... Strategic Business Report" report to their offering. ... This report analyzes the Global ... Annual estimates and forecasts are provided for the period 2014 through ... research. The report profiles 25 companies including many ...
(Date:3/23/2017)... ... March 23, 2017 , ... AxioMed ... both viscous and elastic characteristics when deformed, which is identical to how the ... gently absorb compressive forces and return to its natural state along a hysteresis ...
Breaking Biology Technology: