Navigation Links
Children's Hospital of Philadelphia receives federal grant to improve health care decision-making
Date:1/14/2013

The Children's Hospital of Philadelphia (CHOP) was awarded nearly $2M in research funding from the Patient-Centered Outcomes Research Institute (PCORI) to study antibiotic delivery to children returning home after hospitalization for a severe bacterial infection.

The CHOP research is one of 25 projects totaling $40.7M selected from a pool of 500 applicants by PCORI's Board of Governors following a competitive, multi-stage review process involving scientists, patients, caregivers and other stakeholders. Proposals were evaluated on the basis of scientific merit, engagement of patients and stakeholders, methodological rigor and fit within PCORI's National Priorities for Research and Research Agenda.

When a child hospitalized with a serious bacterial infection is discharged, clinicians have two options: (1) transition from the intravenous antibiotics used in the hospital to a prolonged course of oral antibiotics at home; or (2) insert a central venous catheter (PICC) into a large vein in the chest and train the parents in care of the PICC and administration of intravenous antibiotics at home. "These two antibiotic treatment options have major implications for the overall experience of the child, families and caregivers, but there is a lack of real-world evidence on their benefits and drawbacks to help clinicians and patient families make an informed choice," said Ron Keren, MD, MPH, who is leading the study and also directs the Center for Pediatric Clinical Effectiveness (CPCE) at CHOP. "If we find that the prolonged IV option is no better than the oral route, we think that most families would prefer for their child to take oral antibiotics."

In addition to studying the risks and benefits to each treatment choice, the research team will also include parent-investigators, who will inform the research questions being asked and advise the team on how best to communicate the pros and cons of each treatment option to parents.

"
'/>"/>

Contact: Dana Mortensen
mortensen@email.chop.edu
267-426-6092
Children's Hospital of Philadelphia
Source:Eurekalert

Page: 1 2

Related biology news :

1. Hydrogen peroxide vapor enhances hospital disinfection of superbugs
2. Worries about dementia how hospitalization affects the elderly
3. Rhode Island Hospital: Adult entertainment workers likely to benefit from health care intervention
4. RI Hospital: Use of PMP may increase demand for drug treatment, reduce painkiller abuse
5. BGI and the Childrens Hospital of Philadelphia launch the 1,000 Rare Diseases Project
6. How alert hospital employees improved hospitals MSRA infection rate
7. $500,000 Gruber Foundation Genetics Prize goes to Philadelphia scientist
8. Bloomberg School receives $28 million for family planning advocacy
9. UC Riverside turfgrass specialist receives high honor
10. University of Illinois receives grant to study ozone resistance in corn
11. CU-led team receives $9.2 million DOE grant to engineer E. coli into biofuels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... tiny strands of nucleic acid that contain instructions for ... data, our DNA is copied into RNA molecules, which ... in our cells. , Several years ago, scientists ... other known RNAs, this molecule is circular, and was ... has been known about how they are produced. Moreover, ...
(Date:9/18/2014)... and ethnic groups describe losing eyesight as potentially ... more so than other conditions including: loss of ... 49% of non-Hispanic whites, 43% of Asians and ... ailment is the worst that could happen to ... AIDS/HIV. Hispanics and Asians ranked cancer first ...
(Date:9/18/2014)... devastated algal forests in the eastern Mediterranean Sea pose ... their distribution continues to expand as the climate warms, ... team of researchers led by Dr Adriana Vergs of ... Institute for Advanced Studies in Spain, is published in ... team surveyed more than 1000 kilometres of coastline in ...
Breaking Biology News(10 mins):Scientists find how mysterious 'circular RNA' is formed, claim muscular dystrophy link 2Americans rate losing eyesight as having greatest impact on their lives 2Americans rate losing eyesight as having greatest impact on their lives 3Tropical fish a threat to Mediterranean Sea ecosystems 2
... in protecting us from diseases, but how does it ... that before dendritic cells move to the lymph nodes ... move much faster. Immature dendritic cells patrol the tissues ... they undergo a rigorous maturation process. During this maturation ...
... A stunning discovery based on epigenetics (the inheritance of ... nutrient found in eggs and other foodsduring pregnancy may ... This finding by a team of biologists at Boston ... pregnancy to breast cancer. It also is the first ...
... who have had the common chest wall deformity known ... ability to exercise, according to a study published December ... conducted at 11 North American hospitals, involved telephone interviews ... 8 and 21 who had pectus excavatum surgery. ...
Cached Biology News:Immune cells reveal fancy footwork 2Eating eggs when pregnant affects breast cancer in offspring 2Marked improvement in body image, physical stamina, post-surgical pectus patients report 2Marked improvement in body image, physical stamina, post-surgical pectus patients report 3
(Date:9/18/2014)... KEEGO HARBOR, Mich. , Sept. 18, 2014  Health ... -based biotech firm investigating early-stage algae bioactive compounds and metabolic ... member to the company,s board of directors. Ms. Nola ... executive and investment advisor joined the board effective September 17, ... have Ms. Masterson agree to join our board," states ...
(Date:9/18/2014)... 18, 2014 Texas Governor Rick ... Texas A&M Health Science Center CEO Brett Giroir, ... Health and Human Services (HHS), State of Texas ... pandemic influenza vaccine manufacturing facility in Bryan, Texas, ... for the Texas A&M Biocorridor – a rapidly ...
(Date:9/18/2014)... Sept. 18, 2014 Research and Markets ... and Chinese Stem Cell Industry Report, 2014-2017" report ... undifferentiated biological cells that can differentiate into specialized cells ... cells. Stem cell therapy can be applied to treatment ... disease), nervous system diseases, damage or lesion of liver, ...
(Date:9/18/2014)... Research and Markets has announced the addition ... report to their offering. The ... and in-depth study on the current state of the ... a basic overview of the industry including definitions, classifications, ... analysis is provided for the international markets including development ...
Breaking Biology Technology:Health Enhancement Announces New Board Member In Advance Of Annual Shareholder Meeting 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 3Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 4Global and Chinese Stem Cell Industry Report, 2014-2017 2Global and Chinese Stem Cell Industry Report, 2014-2017 3Global Human Albumin Industry Report 2014 2Global Human Albumin Industry Report 2014 3
... Sheboygan, Wis. - Gov. Jim Doyle ... the Wisconsin Aerospace Authority - both of whom expressed ... for future space travel. , ,Mark Hanna, a city ... program, will join several already-named nominees for the commission, ...
... will have the exclusive global distribution rights to a stem ... with its developer, ThermoGenesis . , ,Under the terms ... product, known as the Auto Express System, to the ... of private umbilical cord blood banks. The AXP System extracts ...
... took another turn last month when the District Court of ... Cigar, Inc ., v. GoTo.com, Inc . , ,Plaintiff ... of Yahoo! , ,GoTo sold several keywords, ... various JR Cigar competitors. , ,As mentioned in my prior ...
Cached Biology Technology:Wisconsin spaceport committee moves closer to formation 2Are consumers confused by search engine ads? 2Are consumers confused by search engine ads? 3Are consumers confused by search engine ads? 4
... applications for the use of small interfering ... via the RNA interference (RNAi) pathway have ... molecular biology fields. siRNA for experimental use ... or enzymatically, and then transfected into the ...
... is commonly used as a fusion partner ... The GSTTag sequence has been reported to ... the solubility of its fusion partners. When ... GSTTag fusion proteins can be purified with ...
a1-Antitrypsin (human, alpha-1 AT)...
... demands of the routine trace metal analytical ... robust and simple to use instrumentation. The ... most challenging sample matrices found in the ... the toughest analytical challenges found in the ...
Biology Products: