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Childrens Hospital LA discovers growth factor essential to epicardial cell function
Date:10/5/2010

s consistent with embryonic development in the regenerated zebrafish hearts.

The team also found that when PDGF signaling was blocked, epicardial cell proliferation, expression of the embryonic biochemical markers, and coronary blood vessel development were impaired.

"By understanding the mechanism involved in developing a new blood supply to injured cardiac tissue, we can begin to develop a therapeutic strategy for the treatment of heart disease in humans," noted Dr. David Warburton, director of Developmental Biology and Regenerative Medicine at The Saban Research Institute.


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Contact: Ellin Kavanagh
ekavanagh@chla.usc.edu
323-361-8505
Children's Hospital Los Angeles
Source:Eurekalert  

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