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Children of lower socioeconomic status grow up more susceptible to catching colds, Carnegie Mellon researchers find
Date:11/1/2013

Researchers at Carnegie Mellon University have found an association between lower socioeconomic status during childhood and adolescence and the length of telomeres, protective cap-like protein complexes at the end of chromosomes, that ultimately affects the susceptibility to colds in middle-aged adults.

Published in Brain, Behavior and Immunity, the study showed that children and teens with parents of lower socioeconomic status have shorter telomeres as adults. Telomere length is a biomarker of aging with telomeres shortening with age. As a cell's telomeres shorten, it loses its ability to function normally and eventually dies. Having shorter telomeres is connected to the early onset of illnesses such as cardiovascular disease and cancer, with mortality in older adults and, as CMU's Sheldon Cohen first discovered, predicts susceptibility to acute infectious disease in young to midlife adults. This new research now links low childhood socioeconomic status to shorter telomeres and an increased susceptibility to the common cold.

"This provides valuable insight into how our childhood environments can influence our adult health," said Cohen, the Robert E. Doherty Professor of Psychology in CMU's Dietrich College of Humanities and Social Sciences.

In the study, Cohen and his team measured the telomere lengths of white blood cells from 152 healthy volunteers between the ages of 18 and 55. To gauge childhood and current socioeconomic status, the participants reported whether they currently own their home and whether their parents owned the family home when they were between the ages of 1 and 18. They were then exposed to a rhinovirus, which causes a common cold, and quarantined for five days to see if they actually developed an upper respiratory infection.

The results showed that participants with lower childhood socioeconomic status indicated by fewer years that their parents were homeowners had shorter than average t
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Contact: Shilo Rea
shilo@cmu.edu
412-268-6094
Carnegie Mellon University
Source:Eurekalert  

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