Navigation Links
Children born after assisted reproduction at greater risk of congenital malformations
Date:6/13/2010

Gothenburg, Sweden: Couples considering undergoing assisted reproductive technology (ART) treatment should be informed about the increased risk of congenital malformation posed by the use of ART, the annual conference of the European Society of Human Genetics will hear today (Monday). Dr. Graldine Viot, a clinical geneticist at the Maternit Port Royal hospital, Paris, France, will say that she believed that most doctors working in ART clinics in France only told couples about such risks if they were asked specific questions.

Dr. Viot and colleagues conducted a survey in 33 French centres registered for ART, around one third of the total number of clinics registered to perform ART procedures in France. All ART births from these clinics from 2003 to 2007 were included; 15 162 children in total. The study was the largest to date on this subject. Questionnaires were completed both by the parents and the paediatrician and the prevalence of malformations found compared with the data obtained from national registers and in published papers.

"We found a major congenital malformation in 4.24% of the children", said Dr. Viot, "compared with the 2-3% that we had expected from previous published studies. This higher rate was due in part to an excess of heart diseases and malformations of the uro-genital system. This was much more common in boys. Among the minor malformations, we found a five times higher rate of angioma, benign tumours made up of small blood vessels on or near the surface of the skin. These occurred more than twice as frequently in girls than boys."

However, the scientists say, their results are a long way from the 11% of major malformations that have been reported by some studies. "Given that our study is the largest to date, we think that our data are more likely to be statistically representative of the true picture", said Dr. Viot.

The average age of the parents of children born with malformations was not
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society of Human Genetics
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Community interventions and in-home visits may slow excess weight gain in American Indian children
2. Comprehensive overview of Childrens Interstitial Lung Disease (chILD) in special issue of Pediatric Allergy, Immunology, and Pulmonology
3. New forensics research will help identify remains of children
4. Texas Childrens Hospital vaccine experts present 4 studies
5. British Indian children have better mental health
6. Vigorous exercise strengthens hip bones in young children
7. NIH awards $7.5 million to study MRI as a tool to evaluate children with muscular dystrophy
8. Drinking alcohol during pregnancy could lead to acute myeloid leukemia in children
9. ADA releases updated position paper on nutrition assistance programs for children
10. Disease caused by insect bites can be transmitted to children at birth
11. Home medication errors common among children with chronic conditions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/18/2014)... 2,000 patients referred for evaluation of suspected genetic ... for 25 percent, including detection of a number ... to disease, according to a study appearing in ... to coincide with the American Society of Human ... exons or coding regions of thousands of genes ...
(Date:10/17/2014)... German . Why ... order to reproduce? And why are there two sexes anyway? ... issue of the research journal Molecular Human Reproduction ... from Bielefeld University Bielefeld has compiled this special issue on ... female to copulate with several males in quick succession – ...
(Date:10/16/2014)... Cancer constantly wages war on the human body. ... a stalemate. In pancreatic cancer, this stalemate—known as ... becoming aggressively malignant, a phenomena that is poorly ... in the laboratory of Salvatore Torquato, a Professor ... the conditions surrounding tumor dormancy and the switch ...
Breaking Biology News(10 mins):Whole-exome sequencing shows potential as diagnostic tool 2Sperm wars 2Modeling tumor dormancy 2
... Food and Drug Administration (FDA) has granted approval to ... Alza Corporation's Duragesic Patch (Fentanyl Transdermal System) used to ... be managed with alternative analgesics. When applied to the ... medication that is slowly absorbed into the body through ...
... found that introducing a growth factor protein into a mouth ... according to a new paper in the February issue of ... sizeable mouth wound, replacing a tooth takes more than simply ... to anchor the new tooth in place. Such reconstructive surgery ...
... protein called IRE1, which helps stressed-out cells make new ... believed. A new study by researchers from the University ... Institute reveals the surprising finding that this same signaling ... called B lymphocytes. , "This is a unique signaling ...
Cached Biology News:Gene therapy promising for growing tooth-supporting bone 2Gene therapy promising for growing tooth-supporting bone 3Multi-purpose protein regulates new protein synthesis and immune cell development 2Multi-purpose protein regulates new protein synthesis and immune cell development 3
(Date:10/22/2014)... VANCOUVER , Oct. 22, 2014 /PRNewswire/ - iCo ... ICOTF), today announced next steps for its Oral ... findings from its in vitro work ... therapy.  iCo now plans to complete pre clinical ... an initial Phase 1A clinical trial, utilizing approximately ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 The ... (Medication Dispensing Systems, Packaging and Labeling Systems, Table-top ... Automation) - Global Forecasts & Trends to 2019” ... and opportunities in North America, Europe, Asia-Pacific, and ... 101 market tables and 30 figures spread through ...
(Date:10/20/2014)... 20, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the ... Q3 orders to $5.8 million and provides a good start to ... North America and one in the ... projects at record levels," said Peter Bruijns , President & ... end of Q3 than they have been for any complete year ...
(Date:10/20/2014)... October 20, 2014 OncLive® ... Kimmel Cancer Center at Thomas Jefferson University has ... Through the Strategic Alliance Partnership program, the Sidney ... collaborate to raise awareness of the Center’s cutting-edge ... other projects. Clinicians and other health care professionals ...
Breaking Biology Technology:iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 2Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 4Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3
... - MacoPharma increased its forecast for P-Capt(R) filters sale in 2008;, - Use of affinity prion adsorbent for ... in excess of $25 M over the next 5 years ... - $4 M in 2008;,- 10th product approved by the FDA and or the EMEA, contributing ... growth., MONTREAL, ...
... Cholesterol Test Can Help Identify Patients At Risk of Heart ... ... Atherotech, Inc., a,cardio-diagnostic company, today announced that the largest private,insurers in ... (FEHB) Program now cover the VAP (Vertical Auto Profile),Test, the most ...
... Software Platform Further Solidifies Netsmart as Leader in Behavioral Healthcare ... ... Florida, GREAT RIVER, N.Y., Feb. 6 Netsmart Technologies, Inc.,a ... organizations, today announced it has signed a contract to,provide comprehensive licensed ...
Cached Biology Technology:ProMetic provides business update - Over $35 million worth of business secured in January 2ProMetic provides business update - Over $35 million worth of business secured in January 3ProMetic provides business update - Over $35 million worth of business secured in January 4VAP Cholesterol Test From Atherotech Covers 90 Percent of Arizona Insured 2Netsmart Technologies Extends Relationship with Manatee Glens for Enterprise Behavioral Health Software Solutions 2Netsmart Technologies Extends Relationship with Manatee Glens for Enterprise Behavioral Health Software Solutions 3
... Biosearch Technologies has been at the ... accelerate the discovery and application of ... FRET probes and primers or 100 ... applications, Biosearch can meet your most ...
Cultrex 3D Culture Matrix Rat Collagen I....
UNIVERSAL SCORECARD DNA, 1 EA. * Category: Reagents/Consumables....
Cultrex 3D Culture Matrix Laminin I....
Biology Products: