Navigation Links
Chemists' work with small peptide chains may revolutionize study of enzymes and diseases
Date:4/4/2014

ing suggests that amyloids, whose buildup leads to Alzheimer's in the brain, may also have served as the blueprint for larger, modern-day enzymes."

That's good news for researchers such as Korendovych, who thinks this finding may lead to the development of a new class of synthetic peptide-based catalysts. "The amyloid structures we've created may have a more complex biochemistry than we've realized," he says.

There are 20 naturally occurring amino acids, all of which serve as the building blocks of proteins and assist with metabolism.

An enzyme is a type of protein that is composed of at least 100 amino acids and speeds up reactions in a cell.

Korendovych says that, despite an astronomically large number of possible enzymes (each with a different amino acid sequence and three-dimensional shape), only a small number of them actually work.

"Each enzyme has to be an exact fit for its respective substrate," he says, referring to the molecule with which an enzyme reacts. "Even after millions of years, nature is still testing all the possible combinations of enzymes to determine which ones can catalyze metabolic reactions. Our results make an argument for the design of self-assembling nanostructured catalysts."


'/>"/>

Contact: Rob Enslin
rmenslin@syr.edu
315-443-3403
Syracuse University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Notre Dame chemists discover new class of antibiotics
2. Mentoring the next generation of black chemists (video)
3. CCNY chemists use sugar-based gelators to solidify vegetable oils
4. Biochemists find incomplete protein digestion is a useful thing for some bacteria
5. CCNY chemists devise new way to prepare molecules for drug testing
6. Biochemists uphold law of physics
7. University of Wisconsin chemists find new compounds to curb staph infection
8. UCI chemists devise inexpensive, accurate way to detect prostate cancer
9. Chemists devise inexpensive, benchtop method for marking and selecting cells
10. Chemists develop reversible method of tagging proteins
11. Chemists advance clear conductive thin films
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chemists' work with small peptide chains may revolutionize study of enzymes and diseases
(Date:12/17/2014)... Dec. 16, 2014 Research and Markets ... of the "Global Chemical Sensor Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 One major ... demand for medical sensors in biomedical applications. Chemical ... quick and correct diagnosis during surgical procedures. The ...
(Date:12/11/2014)... WINSTON SALEM, N.C. , Dec. 10, 2014  That ... known for quite a while. Hypertension – the medical term ... disease in the early 1800s, and the inflatable cuff that,s ... That doesn,t, however, mean there,s nothing new about hypertension, ... punctured some long-held beliefs about the condition and the best ...
(Date:12/10/2014)... 2014 CIE San Diego has launched an ... connective tissue that enhances care coordination among social service ... client-level information; earned a second $1 million grant from ... seniors aging in community and; will be recognized as ... th 4-6p. CIE San Diego today ...
Breaking Biology News(10 mins):Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... MADISON Denizens of oceans, lakes and even ... in intricately patterned, glass-like shells. Curiously, these tiny phytoplankton ... chips., Diatoms build their hard cell walls by laying ... the key material of the semiconductor industrysilicon. If we ...
... of Exeter has highlighted the problems of reintroducing ... online in the journal Biological Conservation, the research ... that are released into their natural habitats. On ... in the wild, with most deaths related to ...
... This release is available in French and ... Scherrer Institute (PSI) and the EPFL in Switzerland have ... at wavelengths used in typical medical and industrial imaging ... x-ray radiographs and could be used to diagnose the ...
Cached Biology News:In diatom, scientists find genes that may level engineering hurdle 2Captive carnivores not up to wild living 2New technology sharpens X-ray vision 2
(Date:12/17/2014)... , Dec. 17, 2014 CASI Pharmaceuticals, Inc. ... to the acquisition, development and commercialization of innovative therapeutics ... global market with a primary commercial focus on ... been granted a Type C meeting with the U.S. ... will be held in February 2015.  During this meeting ...
(Date:12/15/2014)... 15, 2014 METTLER TOLEDO is ... tool, ParticleView V19 with PVM technology , ... particle vision and measurement tool continuously captures high-resolution ... ParticleView V19 then automatically prepares a report pairing ... size and concentration changes. This compelling blend of ...
(Date:12/15/2014)... 15, 2014  GlassesOff Inc. (OTCBB: GLSO) announced today ... an independent director of the Company,s Board of Directors. ... served as its CEO until its acquisition by ... million transaction. Recognized as the inventor of the first ... provided Wi-Fi -based RFID solutions focused on improving operational ...
(Date:12/13/2014)... CanDiag, Inc., a University of North Carolina ... name to OncoTab, Inc. , “The new name ... today,” said CEO and Chief Science Officer, Dr. Pinku ... cancer diagnostics to include imaging and therapies, and our ... Founded in 2011 by Dr. Mukherjee, an Irwin Belk ...
Breaking Biology Technology:CASI Pharmaceuticals Granted Type C Meeting With U.S. FDA For ENMD-2076 In Fibrolamellar Carcinoma 2CASI Pharmaceuticals Granted Type C Meeting With U.S. FDA For ENMD-2076 In Fibrolamellar Carcinoma 3CASI Pharmaceuticals Granted Type C Meeting With U.S. FDA For ENMD-2076 In Fibrolamellar Carcinoma 4CASI Pharmaceuticals Granted Type C Meeting With U.S. FDA For ENMD-2076 In Fibrolamellar Carcinoma 5New Real-Time In Situ Probe-Based Video Microscope from METTLER TOLEDO 2AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3CanDiag Inc. Expands Product Scope Under a New Name: OncoTab, Inc. 2
... Customer Potential Management , a developer of databases ... relationship management solution has been implemented at the Michigan ... used the CRM solution to promote its collaboration with ... partnership with oncologists from both hospitals. While market research ...
... last week that he is planning to have a ... will provide access to his electronic medical records. ... Foundation announced that it has licensed California research firm ... On another note, Madison biotech firm Platypus Technologies ...
... care sector venture capital shows Wisconsin near the bottom for investments ... up as the state's investment funds begin a new cycle. ... formation and management counseling service specializing in the health care sector. ... is we felt like a lot of the deals that were ...
Cached Biology Technology:Wisconsin ranks low in mid-year health care capital investment report 2Wisconsin ranks low in mid-year health care capital investment report 3