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Chemists unlock potential target for drug development
Date:1/19/2012

sing different additives or enzymes the results did not prove fruitful in studying the receptor.

What Spence and his team found is that by adding a simple molecule called NF449 originally thought to block the receptor they were able to activate the P2X1 receptor in platelets after a blood draw.

"We have discovered a way to prepare and handle platelets so that we can study the receptor authentically," he said. "This research opens up new avenues of study and will allow researchers and pharmaceutical companies to re-appraise this receptor as a druggable target."


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Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert  

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