Navigation Links
Chemists synthesize artificial cell membrane
Date:1/25/2012

Chemists have taken an important step in making artificial life forms from scratch. Using a novel chemical reaction, they have created self-assembling cell membranes, the structural envelopes that contain and support the reactions required for life.

Neal Devaraj, assistant professor of chemistry at the University of California, San Diego, and Itay Budin, a graduate student at Harvard University, report their success in the Journal of the American Chemical Society.

"One of our long term, very ambitious goals is to try to make an artificial cell, a synthetic living unit from the bottom up to make a living organism from non-living molecules that have never been through or touched a living organism," Devaraj said. "Presumably this occurred at some point in the past. Otherwise life wouldn't exist."

By assembling an essential component of earthly life with no biological precursors, they hope to illuminate life's origins.

"We don't understand this really fundamental step in our existence, which is how non-living matter went to living matter," Devaraj said. "So this is a really ripe area to try to understand what knowledge we lack about how that transition might have occurred. That could teach us a lot even the basic chemical, biological principles that are necessary for life."

Molecules that make up cell membranes have heads that mix easily with water and tails that repel it. In water, they form a double layer with heads out and tails in, a barrier that sequesters the contents of the cell.

Devaraj and Budin created similar molecules with a novel reaction that joins two chains of lipids. Nature uses complex enzymes that are themselves embedded in membranes to accomplish this, making it hard to understand how the very first membranes came to be.

"In our system, we use a sort of primitive catalyst, a very simple metal ion," Devaraj said. "The reaction itself is completely artificial. There's no biolo
'/>"/>

Contact: Neal Devaraj
scinews@ucsd.edu
University of California - San Diego
Source:Eurekalert

Page: 1 2

Related biology news :

1. Chemists unlock potential target for drug development
2. Chemists reveal the force within you
3. Clemson University biochemists identify new genetic code repair tool
4. Tel Aviv Universitys Sackler Prizes awarded to 2 North American chemists
5. K-State chemists biosensor may improve food, water safety and cancer detection
6. UCSB chemists make discovery that may lead to drug treatment possibilities for Alzheimers
7. Chemists turn gold to purple -- on purpose
8. Chemists document workings of key staph enzyme -- and how to block it
9. US launches International Year of Chemistry Feb. 1 with panel of world-renowned chemists
10. Chemists concoct new agents to easily study critical cell proteins
11. Team of chemists produces biodiesel at their university, using used cooking oil as a basis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... Aug. 04, 2015 ... has announced the addition of the ... and Service), Sub-Segment (Computer Forensics, Network Forensics, ... Types, Service, Vertical and Region - Global ... offering. By Component (Hardware, Software, ...
(Date:7/31/2015)... 31. juli 2015 Den 10. internationale konference ... BGI fra den 22. - 25. oktober i ... sin 10-års fødselsdag i år. Siden starten i 2006 ... møder på ,omik,-feltet, og er en af de mest ... ICG-10 fokuserer på nylige gennembrud og fremskridt inden for ...
(Date:7/31/2015)... Chine, 31 juillet 2015 La 10e ... ) sera organisée par le BGI du 22 ... en Chine. La conférence ... inauguration en 2006, l,ICG est devenue l,une des ... domaine des « omiques » et c,est aussi la plus ...
Breaking Biology News(10 mins):Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 3
... political targets to significantly reduce and halt biodiversity loss. ... setting up of new targets for 2020. In addition, ... been incorporated in several global and the EU agendas ... a critical review of the existing and emerging biodiversity ...
... marked the deadline for the political targets to significantly ... the 2010 goal stimulated the setting up of new ... ecosystems and their services has been incorporated in several ... meet these challenging targets requires a critical review of ...
... the University of California, Riverside,s College of Engineering ... with the state of California to develop diesel formulations ... supports several California legislative measures and regulations that aim ... greenhouse gases. These include AB 32, which requires the ...
Cached Biology News:Biodiversity conservation depends on scale: Lessons from the science-policy dialogue 2Biodiversity conservation depends on scale: Lessons from the sience-policy dialogue 2UC Riverside developing biofuel formulations for California 2UC Riverside developing biofuel formulations for California 3
(Date:8/27/2015)... ... August 27, 2015 , ... ... recently presented new data on the relationship of genetics and hypertension at the ... on Heart Disease in Vancouver, British Columbia, Canada. The event, which boasts an ...
(Date:8/26/2015)... , ... August 26, 2015 , ... ... increasing its investment in the development and manufacture of highly valued cardiac markers ... company’s scientific team's extensive expertise with protein chemistry has led to the development ...
(Date:8/26/2015)... BEIJING , August 26, 2015 ... DiaCardio wins 1 st place  Wayerz ... led in Israel by venture capital fund ... countries including the US, China , ... Latin America .  Impressive achievement for the Israeli ...
(Date:8/26/2015)... ... August 26, 2015 , ... PRC Clinical, a Clinical Trial Management ... local sponsors in southern California. The Clinical Trial Management Expert CRO seeks to introduce ... pathways., , Stem Cell Meeting on the Mesa ...
Breaking Biology Technology:Proove Biosciences Presents Ground-Breaking Data on Genetics and Heart Disease at 20th World Congress on Heart Disease 2Proove Biosciences Presents Ground-Breaking Data on Genetics and Heart Disease at 20th World Congress on Heart Disease 3Lee Biosolutions Announces Increased Investment in the Development and Manufacturing of Biomarkers Used in Early Detection Of Heart Disease 2Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 2Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 3Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 4Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 5Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 6PRC Clinical To Attend Major Industry Conferences And Meet Sponsor Companies In The San Diego Biotech Hub 2PRC Clinical To Attend Major Industry Conferences And Meet Sponsor Companies In The San Diego Biotech Hub 3
... on an article on "The Final Death Knell of Chicago's ... walls of the demise of Searle due to the latest ... in Chicago. Since then, the Searle name has virtually disappeared ... I wrote on May 16, 2005, titled " Creating thousands ...
... biotech firm NimbleGen Systems Inc. closed its ... venture funding to $50 million, the company said. , ,The ... that can have thousands of individual genetic samples on them ... large amounts of DNA and do comparisons. , , Cargill ...
... As the deadline to finalize the lineup for DEMO 2006 ... just what constitutes a product launch. , ,Does a product ... or a well-tested application qualify as launch-ready? Must I ... order to launch? What about a shipping product that we've ...
Cached Biology Technology:Searle spirit lives on in Chicago as alumni celebrate at former home 2Searle spirit lives on in Chicago as alumni celebrate at former home 3Searle spirit lives on in Chicago as alumni celebrate at former home 4Searle spirit lives on in Chicago as alumni celebrate at former home 5When do you go from "beta" to "product launch"? 2When do you go from "beta" to "product launch"? 3
Opticon continuous fluorescence detector; includes optical base, analysis software, computer and monitor (this is an accessory for the DNA Engine thermal cyclers which must be ordered seperately)...
Hybridizer (220 V) For more information, please visit Dako' web-site. EU regulatory status: CE US regulatory status: IVD...
... in vascular proliferation, adhesion, and wound repair ... cell adhesion receptors consists of at least ... and b subunit that associate in a ... of the integrin family are based upon ...
... exchange media are rigid macroporous hydrophilic media. ... rates at moderate pressures, while the macroporous ... the hydrophilic matrix reduces nonspecific binding. Macro-Prep ... anion exchanger with very high flow rates ...
Biology Products: