Navigation Links
Chemists make beds with soft landings
Date:8/17/2008

RICHLAND, Wash. -- Bedsprings aren't often found in biology. Now, chemists have succeeded in making a layer of tiny protein coils attached to a surface, much like miniature bedsprings in a frame. This thin film made of stable and very pure helices can help researchers develop molecular electronics or solar cells, or to divine the biology of proteins.

Physical chemists at the Department of Energy's Pacific Northwest National Laboratory pulled off this design trick using a "soft-landing" technique that disperses the tiny protein coils onto a waiting surface. The small proteins called peptides are of a variety that normally take the shape of a coiled spring or helix in gas phase. The method used by PNNL's Julia Laskin and Peng Wang delivered ultra-pure helical peptides to the surface and trapped them there, they report in July 29 and will appear in print in an upcoming issue of Angewandte Chemie.

"Controlling the conformation of peptides is not easy," said Laskin. "Our previous studies showed that soft-landing can be used to prepare ultrapure peptide layers on substrates. The question we faced was, in addition to controlling purity, can we also control the structure of the molecules? We showed we could."

Researchers have been trying to make thin films of helical peptides for many years. Because the peptides line up in an orderly fashion, the overall chemical nature of the thin films make them useful for a variety of technological applications. They can be modified with light sensitive molecules and turned into components of solar cells; or designed to change shape when a current is applied for molecular electronics. Also, the helices themselves can be used to elicit cues about how proteins function.

After making the thin films out of generic peptides previously, Laskin and Wang wanted to use this method to make a film out of helical peptides, and compare it with a more common method called electrospray.

To do so,
'/>"/>

Contact: Mary Beckman
mary.beckman@pnl.gov
509-375-3688
DOE/Pacific Northwest National Laboratory
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. NIST chemists get scoop on crude oil from pig manure
2. Glowing films developed by UC San Diego chemists reveal traces of explosives
3. Biologists are from Mars, chemists are from Venus?
4. Biochemists reveal details of mysterious bacterial microcompartments
5. Team of chemists receives $5 million grant to develop enzyme mimics
6. Good earth: Brown chemists show origin of soil-scented geosmin
7. Chemists get grip on slippery lipids
8. Clemson chemists discover new way antioxidants fight debilitating diseases
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chemists make beds with soft landings
(Date:11/4/2014)... Nov. 5, 2014 – University of Utah engineers developed ... help jet fuel produce electricity without needing to ignite ... to power portable electronics, off-grid power and sensors. , ... in the American Chemical Society journal ACS Catalysis ... a chemical reaction between a fuel and an oxygen-rich ...
(Date:11/4/2014)... Temple University School of Medicine announced today that ... initiative funded by the Bill & Melinda Gates ... Obstetrics, Gynecology and Reproductive Sciences; and Vice Chair ... School of Medicine will pursue an innovative global ... Biomarkers to Assess Fetal Neurodevelopment.", Grand Challenges Explorations ...
(Date:11/4/2014)... published research study examining only marketing directed at ... food restaurants has found that the majority of ... to such marketing tactics. , Authored by Arizona ... the study is the first to examine the ... exterior of fast food restaurants and its relationship ...
Breaking Biology News(10 mins):Jet-fueled electricity at room temperature 2Temple University School of Medicine receives Grand Challenges Explorations grant 2Fast food marketing for children disproportionately affects certain communities 2Fast food marketing for children disproportionately affects certain communities 3
... BEER-SHEVA, ISRAEL, May 3, 2010 Ben-Gurion University ... strain which produces large amounts of a polyunsaturated fatty ... blood cholesterol level, reducing the risk for heart attacks. ... Biotechnology Lab in the Jacob Blaustein Institutes for Desert ...
... keep the planet cool, but rising levels of carbon dioxide ... According to a new study by researchers at the Carnegie ... of the warming from increased carbon dioxide is due to ... to carbon dioxide,s better-known effect as a heat-trapping greenhouse gas. ...
... (May 3, 2010) Advances in energy conservation, better ... breakthroughs in understanding diseases: These are just a few ... be enabled by an upgrade to the Advanced Photon ... Argonne National Laboratory., DOE today announced formal approval for ...
Cached Biology News:Ben-Gurion U researchers isolate microalgal strain that could reduce cholesterol 2CO2 effects on plants increases global warming 2CO2 effects on plants increases global warming 3Upgrade to advanced photon source announced by DOE 2Upgrade to advanced photon source announced by DOE 3
(Date:11/26/2014)... November 25, 2014 Silicon Valley Electronic ... with RPM Alliance , provider of clinical research ... With the latest addition to its CRO Partnership Program, ... EDC system to India. , “We have found ... and customizable EDC platform which is both user friendly ...
(Date:11/26/2014)... SoundConnect , an award winning ... announce that Darren Suders has joined the team as ... drive the partner program through innovative offerings, ... , Darren brings more than 10-years of channel telecommunication ... channel operations, from policy development, to partner education and ...
(Date:11/26/2014)... -- Theravalues Corporation annuncia con orgoglio il lancio di ... Hi Europe 2014 (dal 2 al 4 dicembre, ... curcumina con la maggiore biodisponibilità di sempre, con una ... dalle norme europee. La curcumina è un ... Curcuma longa ) che è stata associata con attività ...
(Date:11/24/2014)... , Nov. 24, 2014 VolitionRx Limited ... tests for cancer and other conditions, today announced that data ... the Science for Business BioWin Day 2014, being held November ... data come from VolitionRx,s lung cancer pilot study, the samples ... Centre Hospitalier Universitaire (CHU) de Liege in Belgium ...
Breaking Biology Technology:RPM Alliance Joins Clinovo’s CRO Partnership Program, Further Strengthening Its Presence in Southern California and India 2SoundConnect Appoints Director of Channel Development & Sales 2La curcumina con la maggiore biodisponibilità di sempre farà il suo debutto in Europa 2La curcumina con la maggiore biodisponibilità di sempre farà il suo debutto in Europa 3VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 2VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 3VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 4VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 5VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 6
... the Antipsychotic of Choice in All Lines ... New Report from Decision Resources, WALTHAM, Mass., ... leading research and advisory firms focusing on pharmaceutical ... disorder varies,depending on doctor specialty. According to the ...
... Palace Hotel in San Francisco on Wednesday, October ... ... DIEGO, Oct. 2 Favrille, Inc. (Nasdaq:,FVRL), a biopharmaceutical company developing ... Chief Financial Officer, will present at the Biotechnology,Industry Organization (BIO) InvestorForum ...
... ST. LOUIS, Oct. 2 SAFC(R), a ... ), has announced its plans to begin,construction ... ingredients (APIs),conjugation suite at its Pharma sector,s ... to support oncology drug substance requirements,that demand ...
Cached Biology Technology:Patient Treatment for Bipolar Disorder Varies Depending on Doctor Specialty; Well Designed Clinical Trials May Be The Answer 2Patient Treatment for Bipolar Disorder Varies Depending on Doctor Specialty; Well Designed Clinical Trials May Be The Answer 3SAFC Supports Potent API Conjugate Manufacturing With New St. Louis Production Suite 2SAFC Supports Potent API Conjugate Manufacturing With New St. Louis Production Suite 3
Mouse BLC/BCA 1 - 10kDa...
Bag-1 (K-20)...
... PGE2-d4 contains 4 deuterium atoms at ... It is intended for use as an ... E2 (PGE2) by GC- or LC-mass spectrometry. ... products of arachidonic acid and one of ...
Deletions, insertions or substitutions. Mutations in plasmids of size up to 15 kb. Single or multiple mutations...
Biology Products: