Navigation Links
Chemistry resolves toxic concerns about carbon nanotubes
Date:1/15/2013

Safety fears about carbon nanotubes, due to their structural similarity to asbestos, have been alleviated following research showing that reducing their length removes their toxic properties.

In a new study, published today in the journal Angewandte Chemie, evidence is provided that the asbestos-like reactivity and pathogenicity reported for long, pristine nanotubes can be completely alleviated if their surface is modified and their effective length is reduced as a result of chemical treatment.

First atomically described in the 1990s, carbon nanotubes are sheets of carbon atoms rolled up into hollow tubes just a few nanometres in diameter. Engineered carbon nanotubes can be chemically modified, with the addition of chemotherapeutic drugs, fluorescent tags or nucleic acids opening up applications in cancer and gene therapy.

Furthermore, these chemically modified carbon nanotubes can pierce the cell membrane, acting as a kind of 'nano-needle', allowing the possibility of efficient transport of therapeutic and diagnostic agents directly into the cytoplasm of cells.

Among their downsides however, have been concerns about their safety profile. One of the most serious concerns, highlighted in 2008, involves the carcinogenic risk from the exposure and persistence of such fibres in the body. Some studies indicate that when long untreated carbon nanotubes are injected to the abdominal cavity of mice they can induce unwanted responses resembling those associated with exposure to certain asbestos fibres.

In this paper, the authors describe two different reactions which ask if any chemical modification can render the nanotubes non-toxic. They conclude that not all chemical treatments alleviate the toxicity risks associated with the material. Only those reactions that are able to render carbon nanotubes short and stably suspended in biological fluids without aggregation are able to result in safe, risk-free material.<
'/>"/>

Contact: Clare Ryan
clare.ryan@ucl.ac.uk
44-020-310-83846
University College London
Source:Eurekalert

Page: 1 2

Related biology news :

1. LAMIS -- a green chemistry alternative for laser spectroscopy
2. UCLAs Yi Tang receives Presidential Green Chemistry Challenge Award from EPA
3. Pulverized rocks, coral reefs, seawater chemistry, and continental collisions
4. Scientists connect seawater chemistry with climate change and evolution
5. Chemistry on Mars video with Curiosity Rover from the American Chemical Society
6. Changes in water chemistry leave lake critters defenseless
7. New Market Forecasts Available for Critical Global Biotechnology Testing and Screening Markets: Molecular Diagnostics, Hematology, Clinical Chemistry and Nucleic Acid Testing
8. Astrochemistry enters a bold new era with ALMA
9. Emory receives $20 million NSF grant for chemistry center
10. The Journal of Biological Chemistry commemorates an important 1987 discovery
11. Model sheds light on the chemistry that sparked the origin of life
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... July 30, 2015 Cellecta, Inc., a ... function analysis and biomarker discovery, announced the release ... Library targeting all human protein coding genes. CRISPR ... out" a gene,s function. Cellecta,s new Human Whole ... screening tool so that researchers can investigate in ...
(Date:7/23/2015)... , July 23, 2015 Research ... addition of the "Global Outlook of the ... offering. The global biometrics market ... public and commercial applications owing to the uptake ... witness a transformation that enhances the growth of ...
(Date:7/20/2015)... 2015  Acuity Market Intelligence,s latest research "The ... Commerce and Privacy" forecasts that between 2014 and ... be downloaded to smart mobile devices by 2.2 ... is projected to generate more than $67.9 billion ... forecast period.    "Biometrics is at ...
Breaking Biology News(10 mins):CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3Biometrics on Smart Mobile Devices to Redefine Digital Identity with 12.9 Billion Biometric App Downloads between 2014 and 2020 2
... A new study compares the relative rate of molecular evolution ... wanted to know whether evolution marches on at a steady pace ... of individual letters of the genetic code occur more rapidly ... study appears in the Proceedings of the Royal Society B ...
... Ga. - A well-documented suppressor of immunity that,s used ... to change its spots, researchers report. In the ... 2,3-dioxegenase, or IDO, also appears capable of helping key ... the invader, said Dr. Tracy L. McGaha, immunologist at ...
... 7, 2014   Dynasil Corporation of America ("Dynasil" ... developer of sensing, detection and analysis technology for homeland ... has regained compliance with the $1.00 minimum bid price ... As previously announced, on March 26, 2013, ...
Cached Biology News:Of lice and men (and chimps): Study tracks pace of molecular evolution 2Of lice and men (and chimps): Study tracks pace of molecular evolution 3Finding about classic suppressor of immunity points toward new therapies for bad infections 2Finding about classic suppressor of immunity points toward new therapies for bad infections 3Dynasil Regains Compliance with NASDAQ Listing Requirements 2
(Date:7/29/2015)... July 29, 2015 US-Australian drug discovery company, ... confirmed it is committed to progressing its ground-breaking technology ... practicable and to ensure the Company delivers the best ... Iain Ross , said the Company currently had ... pre-clinical programs, discovery programs and academic partnerships and initiatives, ...
(Date:7/29/2015)...  HealthSouth Corporation (NYSE: HLS ), one ... services, offering both facility-based and home-based post-acute services, ... second quarter ended June 30, 2015. ... growth in both segments and an 11.0% increase ... and Chief Executive Officer of HealthSouth. "While reported ...
(Date:7/29/2015)... , July 29, 2015 ... announced the addition of the "Global Biosimilars ... offering. The Global Biosimilars Market, 2015 ... the rapidly growing biosimilars market. With the blockbuster ... to minimize costs, biosimilars are being viewed as ...
(Date:7/29/2015)... 2015  Therapath Neuropathology ( www.Therapath.com ), a ... VA and Military Medical centers both domestically and ... and Sweat Gland Nerve Fiber Density (SGNFD) for ... ). Demonstration of a reduction ... punch skin biopsy is a highly sensitive and ...
Breaking Biology Technology:Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25HealthSouth Reports Results for Second Quarter 2015 26HealthSouth Reports Results for Second Quarter 2015 27
... provide a,sensitive method to detect protease activity, measure ... of drug candidates. LI-COR,Biosciences now offers three different ... BACE, and IRDye 800CW/QC-1 CSP-3., "These substrates ... conjugated dye by our novel IRDye QC-1 quencher," ...
... Studies show that up to 30% of coffees ordered as ,decaf, ... ... Ever wonder whether the,coffee you had after dinner was really decaf? ... caffeine test strip from,Silver Lake Research, the leader in at-home water quality ...
... today that Gemstone Acquisition Corporation, a wholly-owned,subsidiary of ... purchase all,outstanding shares of common stock of Genelabs ... interest and less any required withholding,taxes. The tender ... announced,Agreement and Plan of Merger dated October 29, ...
Cached Biology Technology:LI-COR Introduces Three IRDye(R) Near-Infrared Fluorescence Resonance Energy Transfer (NIR-FRET) Protease Substrates 2Is Your Decaf Really Decaf? 2GlaxoSmithKline Commences Tender Offer to Acquire Genelabs Technologies, Inc. 2GlaxoSmithKline Commences Tender Offer to Acquire Genelabs Technologies, Inc. 3
... leading provider of X-ray crystallography services ... screening services to its pharmaceutical and ... binding of drug-like fragments to the ... targets, allowing scientists to develop novel, ...
...
... acetylcholinesterase (AChE) activity. This is a highly ... non-radioactive and easy to use assay for ... acetylcholine. A series of coupled enzyme reactions ... a change in luminescence. Inhibitors of AChE ...
Rabbit polyclonal to Vitronectin ( Abpromise for all tested applications). Antigen: Full length native Vitronectin (Cow) Entrez Gene ID: 7448 Swiss Protein ID: P04004...
Biology Products: