Navigation Links
Chemistry researchers receive patent for new scientific measurement instrument
Date:5/10/2011

Two Baylor University chemistry professors have invented a new polarimeter, a basic scientific instrument used to measure and interpret the polarization of transverse waves, such as light waves, that could prove useful in determining the purity of pharmaceuticals. Baylor has now patented the device.

Certain compounds differ only in the way that they interact with polarized light. Plane polarized light is light whose electric vector moves back and forth in a plane. When plane polarized light passes through an optically active medium, the plane of polarization is rotated. The device that measures this rotation is called a polarimeter. To measure the rotation with a conventional polarimeter, a polarizing prism must be rotated and this requires some mechanical parts. Dr. Kenneth Busch, emeritus professor of chemistry at Baylor, and Dr. Dennis Rabbe, chemistry laboratory coordinator at Baylor, have developed a polarimeter that differs from others in that it has no moving parts, which eliminates problems associated with wear and tear and possible inaccurate readings.

"Our device uses two prisms whose planes of polarization are fixed at a certain angle with respect to one another," Busch said. "When these prisms are placed in the beam of a solid-state array detector spectrometer, any rotation caused by an optically active compound rotates the plane of polarization. This rotation reduces the amount of light that reaches the detector of the spectrometer. Because we are using a spectrometer, the device monitors the rotation over a range of different wavelengths."

Busch said that by having a range of wavelengths with different rotations, researchers can use multivariate statistics to correlate the spectrometer signal with the optical activity of the sample.

Busch said one application that Baylor's polarimeter could prove useful is in pharmaceuticals. Most pharmaceuticals are optically active compounds composed of enantiomeric pairs. In some cases, one member of an enantiomeric pair is the active ingredient of the drug, while the other may be either inactive or toxic, which makes enantiomeric purity an important factor with drug formulations. Polarimeters are used to determine enantiomeric purity.


'/>"/>

Contact: Matt Pene
Matt_Pene@baylor.edu
254-710-4656
Baylor University
Source:Eurekalert

Related biology news :

1. Research center to free chemistry from Earths bonds
2. Volcanoes may have provided sparks and chemistry for first life
3. The Camille & Henry Dreyfus Foundation to host important symposium on chemistry and the environment
4. Biochemistry of human physiology in health and disease is focus of updated clinical text
5. International public-private partnership offers new paradigm for medicinal chemistry
6. Chemistry professor 1 of only 3 at UH to achieve prestigious AAAS status
7. Phytoplankton cell membranes challenge fundamentals of biochemistry
8. British journal publishes inorganic chemistry research of NJIT professor
9. Peptides-on-demand: McGill researchers radical new green chemistry makes the impossible possible
10. Queens receives $9.1 million to establish National Center of Excellence in green chemistry
11. Better living through chemistry
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... March 30, 2017  On April 6-7, 2017, Sequencing.com ... Genome hackathon at Microsoft,s headquarters in ... will focus on developing health and wellness apps that ... Hack the Genome is the first hackathon for ... world,s largest companies in the genomics, tech and health ...
(Date:3/30/2017)... 30, 2017 Trends, opportunities and forecast in ... by technology (fingerprint, AFIS, iris recognition, facial recognition, hand ... by end use industry (government and law enforcement, commercial ... banking, and others), and by region ( North ... Asia Pacific , and the Rest of ...
(Date:3/28/2017)... , March 28, 2017 ... Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video ... and Region - Global Forecast to 2022", published by ... in 2016 and is projected to reach USD 75.64 ... 2017 and 2022. The base year considered for the ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... ... August 16, 2017 , ... We are proud ... (FDA) inspection at our Dilworth, MN site. The inspection took place Monday, July ... conducted as part of a routine Bioresearch Monitoring Program (BIMO) with the USFDA ...
(Date:8/15/2017)... ... 15, 2017 , ... Nanomedical Diagnostics , a cutting-edge ... the launch of the new NHS Agile biosensor chip . The new ... a wide range of molecules, including small and large molecules, peptides, proteins, and ...
(Date:8/15/2017)... Yorba Linda, Ca (PRWEB) , ... August 15, ... ... world coffee production and is threatened by various biotic and abiotic factors. During ... the complex evolutionary history of coffee, as well as gain a better understanding ...
(Date:8/11/2017)... Md. , Aug. 11, 2017 /PRNewswire/ ... a New York Times article regarding the ... billion, according to Kalorama Information.  The article, ... App for That"  used information from ... Patient Monitoring & Telemedicine Market  (Sleep, Diabetes, ...
Breaking Biology Technology: