Navigation Links
Chemical in blood may explain susceptibility to bladder pain
Date:6/15/2009

recovery, but I don't think we cure them. It's a chronic condition. It's like lactose intolerance you won't get that gene back, but you can learn to avoid milk," he said.

So far, humans with the disorder have the option of bladder distention, dietary changes, exercise, oral drugs, electrical nerve stimulation or surgery. But all treatments target only symptoms because the underlying cause of the disease is unknown.

Buffington plans to test human samples from patients diagnosed with irritable bowel syndrome and fibromyalgia to see if the same biomarker is associated with these chronic pain disorders as well. These disorders, like IC, are categorized as what are known as medically unexplained or functional syndromes, and Buffington has explored the possibility that a common link exists among these types of diseases.

He published a review paper in the April issue of the journal Psychotherapy and Psychosomatics in which he suggested that traumatic events experienced by pregnant females might transmit to fetuses a genetic change associated with the stress response.

Buffington suggests that such a genetic change would mean offspring born to these mothers might then have a genetic predisposition to be more vulnerable to certain stressors, and that in some individuals that vulnerability could lead to development of a chronic pain disorder in response to stress.

"When products of the stress response cross the placenta, they can change gene expression in offspring," Buffington said. "My guess is that there are patterns or groups of genes that are changed. And these groups could have something to do with the magnitude and quality of the stress response. I think it's another useful way to look at how these things develop."


'/>"/>

Contact: Tony Buffington
buffington.1@osu.edu
614-292-7987
Ohio State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
2. American Chemical Societys Weekly PressPac -- Aug. 8, 2007
3. Thermochemical process converts poultry litter into bio-oil
4. New chemically-sensitive MRI scan may bypass some invasive diagnostic tests in next decade
5. Natural chemical found in broccoli helps combat skin blistering disease
6. American Chemical Societys Weekly PressPac -- Aug. 15, 2007
7. American Chemical Societys Weekly Press Pac
8. Amber specimen captures ancient chemical battle
9. American Chemical Societys Weekly Presspac -- Aug. 29, 2007
10. American Chemical Society calls green chemistry bill a smart step
11. Institution of Chemical Engineers chooses Elsevier as publishing partner
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... to prevent Type 2 diabetes, don,t get your hopes up. ... The FASEB Journal , suggests that you don,t ... study compared genetically identical twins-one heavier and one leaner-and found ... those related to Type 2 diabetes, were found in both ... the onset of this type of diabetes is largely influenced ...
(Date:9/2/2014)... your integrity? Tell the truth; everyone has a tipping point. ... we,ll lie if the benefit is great enough. Now, scientists ... make that decision. , The result was published online ... "We prefer to be honest, even if lying is beneficial," ... associate at the Virginia Tech Carilion Research Institute , ...
(Date:9/2/2014)... limestone is well known as a result of ... (for example, Archaeopteryx). Now, for the first time, ... equivalent of these outcrops - discoveries which include ... treader. , Despite the abundance of fossils in ... obtained from the Late Kimmeridgian equivalents of these ...
Breaking Biology News(10 mins):What you eat and not just the number of calories, is a significant factor in diabetes risk 2Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 2Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 3Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 4Exceptionally well preserved insect fossils from the Rhône Valley 2
... Calif. UC Riverside,s Alexander Raikhel , a professor ... National Academy of Sciences (NAS) for his excellence in ... is one of the highest honors given to a scientist ... inducted into the academy next April during its 147th annual ...
... the 61st Annual Meeting of the Rocky Mountain Section ... May 2009 in Orem, Utah. Utah Valley University ... building on the UVU campus. Brigham Young University is ... industry scientists, and graduate and undergraduate students, will highlight ...
... million in U.S. dollars have been awarded to ... studies related to asthma and other immune system ... extramural grants were awarded by the Biomedical Research ... and Research), the government agency driving Singapore,s transformation ...
Cached Biology News:UC Riverside professor receives top scientific honor 2UC Riverside professor receives top scientific honor 3Geoscientists meet to discuss Rocky Mountain geology 2Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants 2Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants 3Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants 4
(Date:9/2/2014)... Sept. 2, 2014  Technology Applications International Corporation (the ... wholly-owned subsidiary Renuell Int,l, Inc. has signed an additional ... Administration ("NASA") at the Johnson Space Center in ... photos: tapplic.com/houstonphotos/ Charles ... pleased to announce our latest, exclusive agreement with NASA. ...
(Date:9/2/2014)... 2014  Xencor, Inc. (NASDAQ: XNCR ... antibodies for the treatment of autoimmune diseases, asthma ... appointment of Debra Zack , M.D., Ph.D., ... Lloyd Rowland , senior vice president, chief ... "Debra,s expertise in biologics clinical development and medical ...
(Date:9/2/2014)... and Rocky Mount, NC (PRWEB) September 02, 2014 ... today the establishment of its 11th clinical research site: ... Research has assumed ownership and operation of the clinical ... Mount, NC, further expanding PMG’s presence in eastern North ... additional 130,000 patients. For the patients in Rocky Mount ...
(Date:9/1/2014)... NEW YORK , Sept. 1, 2014 /PRNewswire/ ... report is available in its catalogue: ... Opportunities, 2019 http://www.reportlinker.com/p02350445/India-Solid-Waste-Management-Vehicles-Market-Forecast-and-Opportunities-2019.html ... municipal corporations are the main governing bodies responsible ... management in cities. On an average, around 135,000 ...
Breaking Biology Technology:Technology Applications International Corporation Subsidiary Enters Into Additional Exclusive Agreement with NASA at a Signing Ceremony at the Johnson Space Center In Houston, Texas 2Technology Applications International Corporation Subsidiary Enters Into Additional Exclusive Agreement with NASA at a Signing Ceremony at the Johnson Space Center In Houston, Texas 3Xencor Appoints Debra Zack, M.D., Ph.D., Vice President, Clinical Development and Lloyd Rowland, Senior Vice President, Chief Compliance Officer and General Counsel 2Xencor Appoints Debra Zack, M.D., Ph.D., Vice President, Clinical Development and Lloyd Rowland, Senior Vice President, Chief Compliance Officer and General Counsel 3PMG Research Announces the Formation of its Eleventh Site 2PMG Research Announces the Formation of its Eleventh Site 3India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 2India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 3India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 4India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 5India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 6India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 7India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 8
... ... the availability of two new atomic force microscope (AFM) probes types with carbon nanotube ... CNT probes offer quantum improvements for AFM imaging, substantially improving results, reducing overall cost ... ...
... FRANCISCO, Calif., June 16 Sunesis Pharmaceuticals, Inc. (Nasdaq: ... and commercialization of new oncology therapeutics for the treatment of ... Executive Officer of Sunesis, will be presenting at the Jefferies ... New York on June 17, 2009. , , The ...
... 16 Three Rivers Pharmaceuticals announced today positive results ... Efficacy of Combined Therapy (DIRECT) clinical trial authored by ... , and colleagues at 44 centers in the United ... (SVR), was achieved demonstrating that INFERGEN provides a second ...
Cached Biology Technology:Carbon Design Innovations, Inc. Introduces Carbon Nanotube Probe Technology for Atomic Force Microscopy, CNT-Probes Deliver New Level of AFM Imaging Performance 2Carbon Design Innovations, Inc. Introduces Carbon Nanotube Probe Technology for Atomic Force Microscopy, CNT-Probes Deliver New Level of AFM Imaging Performance 3Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures 2Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures 3Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures 4
Anti-LC3 Polyclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Mouse monoclonal [SPM325] to Xanthine Oxidase, prediluted ( Abpromise for all tested applications). Antigen: C terminal 358 amino acid fragment of human xanthine oxidase. Entrez Gene ID: 749...
Rabbit polyclonal to Xanthine Oxidase (HRP) ( Abpromise for all tested applications). Antigen: Xanthine Oxidase (from Bovine Buttermilk) Entrez Gene ID: 7498 Swiss Protein ID: P47989...
... Disrupts biological cells for DNA isolation. ... well plates (includes 96 well plate ... lysis across the entire plate length ... Can be used for soil, ...
Biology Products: