Navigation Links
Chemical found in medical devices impairs heart function
Date:4/30/2009

none leaching from these devices varied greatly, all fluid samples contained at least some detectable level of the chemical.

The researchers then injected rats with either a salt solution or a salt solution containing cyclohexanone and measured heart function. Rats that got only salt solution pumped approximately 200 microliters of blood per heartbeat and had an average heart rate of 358 beats per minute, while rats injected with cyclohexanone pumped only about 150 microliters of blood per heartbeat with an average heart rate of 287 beats per minute.

In addition to pumping less blood more slowly, rats injected with cyclohexanone had weaker heart contractions. The team calculated that cyclohexanone caused a 50 percent reduction in the strength of each heart contraction. They also found that the reflex that helps control and maintain blood pressure is much less sensitive after cyclohexanone exposure. Finally, the team observed increased fluid retention and swelling in the rats after cyclohexanone injections.

According to Thompson-Torgerson and Shoukas, they would like to figure out how these side effectsdecreased heart function and swellingoccur and to what degree cyclohexanone is involved. Despite the findings in this study, they emphasize that patients should listen carefully to the advice of their physicians. "We would never recommend that patients decline this type of treatment if they need it," says Shoukas. "On the contrary, such technologies are life-saving medical advances, and their benefits still far outweigh the risks of the associated side effects. As scientists, we are simply trying to understand how the side effects are triggered and what the best method will be to mitigate, and ultimately remedy, these morbidities."


'/>"/>

Contact: Audrey Huang
audrey@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2

Related biology news :

1. Synthetic chemical offers solution for crops facing drought
2. Potentially harmful chemicals found in forest fire smoke
3. American Chemical Societys Weekly PressPac -- April 22, 2009
4. American Chemical Society Weekly PressPac -- April 15, 2009
5. American Chemical Society Weekly PressPac -- April 8, 2009
6. UNC study: Scientists identify chemical compound that may stop deadly brain tumors
7. American Chemical Society Weekly PressPac -- April 1, 2009
8. Engineers develop method to disperse chemically modified graphene in organic solvents
9. Margarita Saenz, M.D. is recipient of Genzyme/ACMGF Fellowship in Biochemical Genetics
10. Microbes in mud flats clean up oil spill chemicals
11. American Chemical Societys weekly PressPac -- March 11, 2009
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/28/2014)... from the National University of Singapore (NUS) have discovered ... breeding and laying direct developing eggs in live bamboo ... white spotted bush frog ( Raorchestes chalazodes ). ... two species known to adopt this novel reproductive strategy. ... London,s Biological Journal of the Linnean Society , ...
(Date:10/27/2014)... punch with a pair of papers that detail how ... Collagen is the most common protein in mammals, a ... support cells and hold organs together. Discovering its secrets ... and cosmetic and reconstructive medicine. , The Rice lab ... a decade, teasing out the details of how it ...
(Date:10/27/2014)... – October 28, 2014 – A new randomized controlled ... blend of collagen and calcium, KoACT®, was far superior ... leaching of calcium from bones and rebuilding new bone ... at: http://www.ncbi.nlm.nih.gov/pubmed/25314004 , ahead of print in ... research was conducted by Bahram H. Arjmandi, PhD, RDN, ...
Breaking Biology News(10 mins):NUS researchers discover for the first time that a rare bush frog breeds in bamboo 2NUS researchers discover for the first time that a rare bush frog breeds in bamboo 3'Sticky' ends start synthetic collagen growth 2'Sticky' ends start synthetic collagen growth 3New RCT: KoACT® beats calcium and vitamin D for optimal bone strength 2
... would happen if a fast-food restaurant reduces the calories ... decreasing the portion size of French fries? Would children ... beverage? Researchers at Cornell University, Dr. Brian Wansink and ... McDonald,s restaurants to answer that question. Prior to ...
... predict sinkholes? What do ancient ambers reveal about paleochemotaxonomy? ... us understand current global warming? Did trilobites venture into ... above sea level? What does the 27 March 2013 ... you reconstruct snapshots of a catastrophic radial current? What ...
... The wild bison roaming Catalina Island are a major attraction ... Island,s most popular destination every year. But managing the number ... endanger the health of the rest of the Island has ... new study by the Catalina Island Conservancy scientists, published in ...
Cached Biology News:Healthier Happy Meals 2New geology research explores intriguing questions 2New geology research explores intriguing questions 3New geology research explores intriguing questions 4New geology research explores intriguing questions 5New geology research explores intriguing questions 6New geology research explores intriguing questions 7New geology research explores intriguing questions 8New geology research explores intriguing questions 9Study finds Catalina Island Conservancy contraception program effectively manages bison population 2
(Date:10/30/2014)... Calif. , Oct. 30, 2014  Ardelyx, ... biopharmaceutical company focused on cardio-renal, gastrointestinal and metabolic ... quarter 2014 financial results on Thursday, November 6, ... will host a live conference call and webcast ... results and provide a business update. ...
(Date:10/30/2014)... Rancho BioSciences , the scientific ... curated public data source TCGA for several ... data is now available for other oncology groups. ... internal data sources for their Pharma, Government and academic ... data that becomes more easily accessible. Rancho advises ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 Grace Century portfolio ... James A. Manganello, Chairman of the Board, to the ... The appointment was made by the Ministry of Health ... 24th, 2014. , More than a year after ... Bill , Prime Minister Perry Christie said the government has ...
(Date:10/30/2014)... (Oct. 29, 2014) – The severe flooding that devastated ... been less destructive if the bridges, roads and other ... new study from the University of Colorado Denver. , ... infrastructure," said Jimmy Kim, PhD, associate professor of structural ... Applied Science and lead author the study. "There is ...
Breaking Biology Technology:Ardelyx to Report Third Quarter 2014 Financial Results on November 6, 2014 2Rancho BioSciences Manually Curated TCGA Data Sets Available 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3CU Denver study says upgrading infrastructure could reduce flood damage 2
... , , , ... ("Rib-X" or the "Company"), a development-stage company focused on ... the treatment of acute care antibiotic-resistant infections, today announced ... the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy ...
... ... MGi scientific camera is being launched into space today as part of ... Naval research Laboratory (NRL) chose the Rolera MGi because of its high ... NASA will transmit the data to the NRL, which will then distribute ...
... In the news release, "Clinical Therapeutics Announces ... for a Refocused Pediatric,Adolescent, & Maternal Therapeutics Section" issued ... PR Newswire, we are advised by a representative,of the ... England",to "Bridgewater, New Jersey" and the contact number has ...
Cached Biology Technology:Rib-X Pharmaceuticals to Present at the 49th ICAAC 2Rib-X Pharmaceuticals to Present at the 49th ICAAC 3Rib-X Pharmaceuticals to Present at the 49th ICAAC 4First Spaceborne Hyperspectral Imager Will Use QImaging Rolera-MGi EMCCD Camera 2/C O R R E C T I O N -- Clinical Therapeutics/ 2/C O R R E C T I O N -- Clinical Therapeutics/ 3/C O R R E C T I O N -- Clinical Therapeutics/ 4/C O R R E C T I O N -- Clinical Therapeutics/ 5