Navigation Links
'Chemical architects' build materials with potential applications in drug delivery and gas storage
Date:6/17/2013

PITTSBURGHHome remodelers understand the concept of improving original foundations with more modern elements. Using this same approachbut with chemistryresearchers in the University of Pittsburgh's Kenneth P. Dietrich School of Arts and Sciences have designed a family of materials that could make drug delivery, gas storage, and gas transport more efficient and at a lower cost. The findings were reported in the latest issue of the Journal of the American Chemical Society (JACS).

The recent work builds upon Pitt Associate Professor of Chemistry Nathaniel Rosi's earlier research published last year in Nature Communications detailing a new class of metal-organic frameworkscrystalline compounds consisting of metal vertices and organic linkers that form porous structures. Last year, Rosi and his team created one of the most porous materials known at the time by changing the size of the vertex (the metal cluster) rather than the length of the organic linkers. Now, in JACS, he and his team have extended those linkers, demonstrating a family of materials even more porousa property necessary for more efficient gas storage.

"We like to think of ourselves as chemical architects," said Rosi, principal investigator of the project. "Our approach always starts with thinking about structure and, in particular, how we can design and manipulate structure. Here, we demonstrate one of the most porous families of metal-organic frameworks known."

Rosi likens his work to that of a builder remodeling a child's chair. As the child grows taller, the legs of the chair become too short. Because the owner likes the structure and integrity of the chair, the owner decides to lengthen its legs instead of purchasing a new one. This is what Rosi and his team have done with their frameworks: they have used one material as a structural blueprint and replaced another element (the organic linkers) to prepare more porous materials.

In additio
'/>"/>

Contact: B. Rose Huber
rhuber@pitt.edu
412-624-4356
University of Pittsburgh
Source:Eurekalert

Page: 1 2

Related biology news :

1. American Chemical Societys highest honor goes to Stephen J. Lippard, Ph.D.
2. Medicine, energy topics of Kavli lectures at American Chemical Society meeting
3. Neurochemical traffic signals may open new avenues for the treatment of schizophrenia
4. New chemical approach to treat Alzheimers
5. Study links chemicals widely found in plastics and processed food to elevated blood pressure in children and teens
6. Save the date: American Chemical Society National Meeting, Sept. 8-12, 2013, in Indianapolis
7. Evonik Industries Selects OPX Biotechnologies for Joint Development of Bio-Based Chemicals
8. R. Graham Cooks wins Dreyfus Prize in the Chemical Sciences
9. American Chemical Society resource connects scientists, discoveries, chemistry & biology interface
10. Scientists map all possible drug-like chemical compounds
11. Middle-schoolers discover novel chemical bond
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... regulate its genes, and adapt to changes in its ... regulation taking place in the truffle, is published in ... illustrates how the truffle deals with its complex genome,s ... may shed light on how traits like aroma and ... known as Prigord truffles, have a syrupy sweet flavor ...
(Date:7/30/2014)... and tended her eggs until they hatched 4.5 years ... in the open-access journal PLOS ONE by ... colleagues. , Octopuses typically have a single reproductive period ... care of their fertilized eggs until they hatch. Shallow-water ... 3 months, but little is known about the brooding ...
(Date:7/30/2014)... Scientists studying the potential effects of climate change ... focusing on the wrong factors, according to a ... Wildlife Conservation Society, University of Queensland, and other ... conservation science is missing the point when it ... majority of climate change scientists focus on the ...
Breaking Biology News(10 mins):How black truffles deal with the jumpers in their genome 2Deep-sea octopus has longest-known egg-brooding period 2Conservation scientists asking wrong questions on climate change impacts on wildlife 2
... Evolutionary biologist Harmit Singh Malik, Ph.D., of Fred Hutchinson ... the Lupus Research Institute to study the potential role ... autoimmune disease. , Malik and colleagues want to find ... autoimmunity., "We want to determine whether autoimmunity when ...
... Parkinson,s and Alzheimer,s is set to take a step ... analysis using automated 3D microscopy. An initiative ... the Eskitis Institute for Cellular and Molecular Biology, the ... of cells as complex as nerve cells in the ...
... A new study led by the University of North ... starting at age 6 months in high-risk infants who later ... autism. "It,s a promising finding," said Jason J. Wolff, ... at UNC,s Carolina Institute for Developmental Disabilities (CIDD). "At this ...
Cached Biology News:Did an evolutionary arms race cause lupus? Biologist Harmit Malik receives grant to try and find out 2Brain-imaging differences evident at 6 months in infants who develop autism 2
(Date:7/31/2014)... BOTHELL, Wash. , July 31, 2014   ... a leading developer, manufacturer and marketer of proprietary clinical ... media and precision thermal shipping products ... Company,s second quarter 2014 financial results will be released ... will host a conference call and live webcast at ...
(Date:7/31/2014)... July 31, 2014 The Kidney Cancer Association ... its monthly news magazine, Kidney Cancer News. , Bill ... on a website maintained by an international news organization. When ... increase in viewers.” , This month’s program highlights news of ... analyzed in a recent study. Kidney Cancer News also ...
(Date:7/31/2014)... 2014 Sales Horizons, a leader in ... sales training course – Mastering the Complex Sale ... , Drawn from proven sales training programs used by ... Complex Sale online sales training course is available to ... face-to-face contact with customers, like technical support, engineers, clinical ...
(Date:7/30/2014)... TARRYTOWN, N.Y. and PARIS ... REGN) and Sanofi (EURONEXT: SAN and NYSE: SNY) today ... Food and Drug Administration (FDA) rare pediatric disease priority ... (BLA) submission for alirocumab.  The priority review voucher entitles ... which provides for an expedited 6-month review from the ...
Breaking Biology Technology:BioLife Solutions to Report Financial Results for Second Quarter 2014 and Provide Business Update on August 7, 2014 2Sales Horizons Offers Mastering the Complex Sale - a Comprehensive, Online Sales Skills Training Course 2Sales Horizons Offers Mastering the Complex Sale - a Comprehensive, Online Sales Skills Training Course 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6
... its potential as a near-term generator of energy efficiencies ... Phillips, director of the Physical, Chemical, and Nano Sciences ... annual meeting. The meeting runs Feb. 18-22 in San ... that solid-state lighting can better utilize existing energy sources ...
... ... ... ... ...
... , MONTREAL , Feb. ... and advanced chemicals technology company, today announced that Mr. ... Vice-President and Chief Financial Officer. , Mr. Ouimet brings ... of executives, with substantial experience in corporate strategy, corporate ...
Cached Biology Technology:CHMP Adopts Negative Opinion for ZEFTERA(TM) 2CHMP Adopts Negative Opinion for ZEFTERA(TM) 3Enerkem appoints new Chief Financial Officer 2
... fixed-angle microcentrifuge rotor at RCF up ... filters consist of a membrane-containing filter ... filter by centrifugation for bacteria removal, ... of cells from media and DNA ...
... Not treated (or medium binding) polystyrene ... binds biomolecules through passive interactions,• Is ... large molecules, such as antibodies, that ... interact with the surface,• Binding capacity ...
... module C, 0.7 mm depth • Reusable, ... can be quickly assembled and disassembled for ... specimens of any thickness with up to ... three chambers per slide. Minimize specimen handling, ...
Comp Dim: chamber diam. depth 20 2.8 mm chamber maximum volume 720 μL...
Biology Products: