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'Chemical architects' build materials with potential applications in drug delivery and gas storage
Date:6/17/2013

PITTSBURGHHome remodelers understand the concept of improving original foundations with more modern elements. Using this same approachbut with chemistryresearchers in the University of Pittsburgh's Kenneth P. Dietrich School of Arts and Sciences have designed a family of materials that could make drug delivery, gas storage, and gas transport more efficient and at a lower cost. The findings were reported in the latest issue of the Journal of the American Chemical Society (JACS).

The recent work builds upon Pitt Associate Professor of Chemistry Nathaniel Rosi's earlier research published last year in Nature Communications detailing a new class of metal-organic frameworkscrystalline compounds consisting of metal vertices and organic linkers that form porous structures. Last year, Rosi and his team created one of the most porous materials known at the time by changing the size of the vertex (the metal cluster) rather than the length of the organic linkers. Now, in JACS, he and his team have extended those linkers, demonstrating a family of materials even more porousa property necessary for more efficient gas storage.

"We like to think of ourselves as chemical architects," said Rosi, principal investigator of the project. "Our approach always starts with thinking about structure and, in particular, how we can design and manipulate structure. Here, we demonstrate one of the most porous families of metal-organic frameworks known."

Rosi likens his work to that of a builder remodeling a child's chair. As the child grows taller, the legs of the chair become too short. Because the owner likes the structure and integrity of the chair, the owner decides to lengthen its legs instead of purchasing a new one. This is what Rosi and his team have done with their frameworks: they have used one material as a structural blueprint and replaced another element (the organic linkers) to prepare more porous materials.

In additio
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Contact: B. Rose Huber
rhuber@pitt.edu
412-624-4356
University of Pittsburgh
Source:Eurekalert

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