COMPASS confirmed previous findings that varenicline side effects, especially nausea, are relatively common. At 3 weeks and 3 months after their target quit date, people with a likely history of depression tended to report these side effects slightly more oftenalthough with no more intensitythan did people without a history of depression.
Feelings of stress and depression tended to decline in both groupswith and without a probable history of depression, said McClure. The trial detected only one serious psychiatric event involving suicidal thoughts and requiring hospitalization. It was in a person who had a previously undisclosed history of bipolar disorder.
|Contact: Rebecca Hughes|
Group Health Cooperative Center for Health Studies