Navigation Links
Cesarean delivery doesn't lower risk of cerebral palsy

Cesarean deliveries do not prevent children from developing cerebral palsy, despite long-held medical and community beliefs about the causes of cerebral palsy, according to new research led by the University of Adelaide.

In the biggest study of its kind, the Australian Collaborative Cerebral Palsy Research Group, based in the University's Robinson Institute, has analyzed all published studies involving more than 3,800 cerebral palsy cases and almost 1.7 million healthy children.

The findings, to be published in the December issue of the journal Obstetrics & Gynecology, show that the risk of cerebral palsy is not lowered by either elective cesarean delivery before labor or emergency cesarean delivery during labor.

"For over a century it was assumed, without good evidence, that most cases of cerebral palsy were due to low oxygen levels or trauma at birth," says research leader Emeritus Professor Alastair MacLennan from the University of Adelaide's Robinson Institute.

"The simple facts are that over the last 40 years, cesarean rates have increased more than six-fold from 5% to 33% in Australia and in many other countries. However, the incidence of cerebral palsy has remained at 2-2.5 per 1000 births," he says.

Lead author and Affiliate Lecturer Dr Michael O'Callaghan says: "This systematic review of the literature clearly shows that the causes of cerebral palsy have little to do with mode of delivery. Therefore, the actual causes of cerebral palsy must lie elsewhere."

The Australian Collaborative Cerebral Palsy Research Group is investigating the probable genetic origins of cerebral palsy.

Emeritus Professor MacLennan says the findings of this study are "clinically important". "This will influence cases of cerebral palsy litigation, where it is often claimed that earlier cesarean delivery would have avoided the cerebral palsy outcome," he says.

"We now need to focus our efforts on finding the antenatal causes of cerebral palsy and their prevention. These may include genetic vulnerability and environmental triggers, such as infection.

"It should be noted that carefully selected cesarean delivery on occasions may prevent stillbirth or reduce the risk of other complications in the newborn, but it will not reduce the risk of cerebral palsy," he says.


Contact: Alastair MacLennan
University of Adelaide

Related biology news :

1. Nanoparticles, pH phoresis could improve cancer drug delivery
2. Vaginal delivery ups risk of pelvic organ prolapse
3. Antibiotics: Change route of delivery to mitigate resistance
4. Chemical architects build materials with potential applications in drug delivery and gas storage
5. Germ-fighting vaccine system makes great strides in delivery
6. Drug delivery strategy eliminates myotonia symptoms in mice with myotonic dystrophy
7. New methods for quantifying antisense drug delivery to target cells and tissues
8. Vaginal delivery is the safest option for women with pelvic girdle pain
9. Researchers create flexible, nanoscale bed of nails for possible drug delivery
10. MVI and Inovio partner to develop malaria vaccines using innovative vaccine delivery tech
11. Nanotechnology drug delivery shows promise for treatment of pediatric cancer
Post Your Comments:
(Date:4/19/2017)... , April 19, 2017 The ... vendor landscape is marked by the presence of several ... however held by five major players - 3M Cogent, ... companies accounted for nearly 61% of the global military ... companies in the global military biometrics market boast global ...
(Date:4/13/2017)... PUNE, India , April 13, 2017 According ... Identity Proofing, Identity Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication ... by MarketsandMarkets™, the IAM Market is expected to grow from USD 14.30 ... Annual Growth Rate (CAGR) of 17.3%. ... ...
(Date:4/11/2017)... April 11, 2017 NXT-ID, Inc. (NASDAQ: ... company, announces the appointment of independent Directors Mr. Robin ... its Board of Directors, furthering the company,s corporate governance and ... Gino Pereira ... look forward to their guidance and benefiting from their considerable ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... The CRISPR-Cas9 ... enabling overexpression experiments and avoiding the use of exogenous expression plasmids. The simplicity ... for performing systematic gain-of-function studies. , This complement to loss-of-function studies, such ...
(Date:10/11/2017)... Palo Alto, CA, USA (PRWEB) , ... October 11, 2017 , ... ... is set to take place on 7th and 8th June 2018 in San Francisco, ... and policy influencers as well as several distinguished CEOs, board directors and government officials ...
(Date:10/11/2017)... 11, 2017  VMS BioMarketing, a leading provider of patient ... Clinical Nurse Educator (CNE) network, which will launch this week. ... among health care professionals to enhance the patient care experience ... and other health care professionals to help women who have ... ...
(Date:10/11/2017)... ... 11, 2017 , ... Disappearing forests and increased emissions are the main causes ... each year. Especially those living in larger cities are affected by air pollution related ... the most pollution-affected countries globally - decided to take action. , “I knew I ...
Breaking Biology Technology: