Navigation Links
Cesarean delivery doesn't lower risk of cerebral palsy
Date:11/18/2013

Cesarean deliveries do not prevent children from developing cerebral palsy, despite long-held medical and community beliefs about the causes of cerebral palsy, according to new research led by the University of Adelaide.

In the biggest study of its kind, the Australian Collaborative Cerebral Palsy Research Group, based in the University's Robinson Institute, has analyzed all published studies involving more than 3,800 cerebral palsy cases and almost 1.7 million healthy children.

The findings, to be published in the December issue of the journal Obstetrics & Gynecology, show that the risk of cerebral palsy is not lowered by either elective cesarean delivery before labor or emergency cesarean delivery during labor.

"For over a century it was assumed, without good evidence, that most cases of cerebral palsy were due to low oxygen levels or trauma at birth," says research leader Emeritus Professor Alastair MacLennan from the University of Adelaide's Robinson Institute.

"The simple facts are that over the last 40 years, cesarean rates have increased more than six-fold from 5% to 33% in Australia and in many other countries. However, the incidence of cerebral palsy has remained at 2-2.5 per 1000 births," he says.

Lead author and Affiliate Lecturer Dr Michael O'Callaghan says: "This systematic review of the literature clearly shows that the causes of cerebral palsy have little to do with mode of delivery. Therefore, the actual causes of cerebral palsy must lie elsewhere."

The Australian Collaborative Cerebral Palsy Research Group is investigating the probable genetic origins of cerebral palsy.

Emeritus Professor MacLennan says the findings of this study are "clinically important". "This will influence cases of cerebral palsy litigation, where it is often claimed that earlier cesarean delivery would have avoided the cerebral palsy outcome," he says.

"We now need to focus our efforts on finding the antenatal causes of cerebral palsy and their prevention. These may include genetic vulnerability and environmental triggers, such as infection.

"It should be noted that carefully selected cesarean delivery on occasions may prevent stillbirth or reduce the risk of other complications in the newborn, but it will not reduce the risk of cerebral palsy," he says.


'/>"/>

Contact: Alastair MacLennan
alastair.maclennan@adelaide.edu.au
61-883-131-337
University of Adelaide
Source:Eurekalert

Related biology news :

1. Nanoparticles, pH phoresis could improve cancer drug delivery
2. Vaginal delivery ups risk of pelvic organ prolapse
3. Antibiotics: Change route of delivery to mitigate resistance
4. Chemical architects build materials with potential applications in drug delivery and gas storage
5. Germ-fighting vaccine system makes great strides in delivery
6. Drug delivery strategy eliminates myotonia symptoms in mice with myotonic dystrophy
7. New methods for quantifying antisense drug delivery to target cells and tissues
8. Vaginal delivery is the safest option for women with pelvic girdle pain
9. Researchers create flexible, nanoscale bed of nails for possible drug delivery
10. MVI and Inovio partner to develop malaria vaccines using innovative vaccine delivery tech
11. Nanotechnology drug delivery shows promise for treatment of pediatric cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/7/2017)... , February 7, 2017 Ipsidy ... Solutions Corporation [OTC: IDGS], ("Ipsidy" or the "Company") a ... transaction processing services, is pleased to announce the following ... Effective January 31, 2017, Philip D. ... Directors, CEO and President.  An experienced payment industry professional ...
(Date:2/2/2017)... NEW YORK , Feb. 2, 2017  EyeLock ... has released a new white paper " What You ... The problem of ensuring user authenticity is a ... protect the authentication of users. However, traditional authentication schemes ... Biometric authentication offers an elegant ...
(Date:1/26/2017)... CITY , Jan. 26, 2017  Crossmatch, a ... unveiled a new solution aimed at combatting fraud, waste ... solution was introduced at the Action on Disaster Relief ... key meeting point for UN agencies and foreign assistance ... Fraud, waste and abuse are a largely unacknowledged ...
Breaking Biology News(10 mins):
(Date:2/24/2017)... ... ... Delpor, Inc. (Delpor), a biotechnology company focused on drug delivery, today announced ... for the further advancement of the company’s 3-month olanzapine product ( DLP-119 ). The ... therapeutic levels of olanzapine for a period of 3 months., “We are honored and ...
(Date:2/24/2017)... , Feb. 24, 2017 Symic Bio, ... developing a new category of therapeutics, announced today the ... SB-030 in peripheral artery disease. The trial will evaluate ... single-use therapeutic, in the reduction of restenosis following angioplasty. ... critical development milestone for SB-030," said Nathan Bachtell ...
(Date:2/24/2017)... Inc. (NASDAQ: CBPO) ("China Biologic" or the "Company"), a leading ... financial results for the fourth quarter and fiscal year of ... Total sales in the fourth quarter of ... 13.6% in USD terms to $77.6 million from $68.3 million ... profit increased by 13.3% to $46.8 million from $41.3 million ...
(Date:2/23/2017)... 2017 ... share data, unaudited)Three Months Ended December 31,Twelve Months Ended ... $           ... 89026%Aldurazyme Net Product Revenue 3539(10)%9498(4)%Kuvan ... Product Revenue  756025%297303(2)%Vimizim Net Product ...
Breaking Biology Technology: