Navigation Links
Central biobank for drug research
Date:9/3/2014

Such quantities are needed because a single drug screening involves testing several million cells. The main biobank facility is being built in the English city of Cambridge and an identical "mirror site" will be set up at the IBMT's Sulzbach location in Germany.

Gently Freezing Cells

The IBMT was brought on board for EBiSC by virtue of the comprehensive expertise it gained through participation in the EU's "Hyperlab" and "CRYSTAL" projects. For EBiSC, IBMT scientists are responsible for freezing the cells and for automating cell cultivation and the biobank itself. For an efficient long-term storage of functional stem cells, they have to be cooled down to temperatures of below 130 degrees Celsius in a controlled way. The scientists have to prepare the cells so they can survive the cold shock of nitrogen gas. The IBMT has, for instance, developed technologies that allow cells to be frozen in an extremely gentle way. "Cells don't like being removed from the surface they are grown on, but that's what people used to do in order to freeze them. Our method allows the cells to stay adherent," explains Neubauer.

Just as with foodstuffs, stem cells depend on an unbroken cold chain to preserve their functionality and viability. The scientists store the cells in special containers or cryotanks each measuring one by two meters. To remove a particular sample, the scientists have to open the cryotank. The problem is that this exposes all the other samples to warmer ambient air, causing them to begin to thaw out. "It's just like when you go to your refrigerator at home it's not a good idea to leave the door open too long," says Neubauer. She and her colleagues at the IBMT and industry partner Askion GmbH have together developed a stem cell biobank complete with protective hoods that protect the other samples whenever the cryotank is opened. In addition to maintaining the temperature, the hoods help keep another key shelf-life criterion, humidit
'/>"/>

Contact: Julia Neubauer
julia.neubauer@ibmt.fraunhofer.de
0049-689-498-0258
Fraunhofer-Gesellschaft
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Flavor and the new Nordic cuisine: BioMed Centrals new scientific journal Flavor is launched
2. GSA North-Central Section Meeting: Change through Time
3. Ben-Gurion U. licenses drug delivery platform for central nervous system diseases to NY biotech firm
4. BioMed Central announces winners of 6th Annual Research Awards
5. Restoring streamside forests helps songbirds survive the winter in Californias Central Valley
6. UN protects wild heart of Central Africa
7. NIH study suggests immune system could play a central role in AMD
8. F1000Research articles will be listed in PubMed, and deposited in PubMed Central
9. Researchers find a better way to culture central nervous cells
10. 24 new species of flower fly have been found in Central and Southern America
11. New evidence shows PubMed Central undermines journal usage
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Central biobank for drug research
(Date:3/24/2015)... GARDENS, Fla. , March 24, 2015 /PRNewswire/ ... identity management solutions, today announced that its U.are.U ... clothing accessory retailer Goorin Bros . to ... Crossmatch biometrics-based solution secures access to the POS ... the increased risk of data breaches. ...
(Date:3/23/2015)... --  HOYOS Labs , a leading global authentication infrastructure ... Company will demonstrate multiple biometrics-based technologies under its identity ... on March 23 through 25, 2015, in ... IEEE Biometric Open Protocol Standard; free biometrics-based consumer app, ... system. BOPS was invented by HOYOS Labs and contributed ...
(Date:3/23/2015)... 23, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... growing mobile commerce market, announces its biometric payment technology, the ... CNBC television starting March 30 th . ... New York markets. ... excited about our new ad campaign following the recent initial ...
Breaking Biology News(10 mins):Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3
... Research Institute scientists has taken a significant step toward answering ... RNA enzymes that can replicate themselves without the help of ... indefinitely. The work was published on Thursday, January ... edition of the journal Science . In the ...
... Calif., January 9, 2009 -- Researchers at the ... that search algorithms used in digital communications can ... led by Giovanni Paternostro, M.D., Ph.D., was published ... PLoS Computational Biology . Using the stack ...
... unveil a novel "two-stage, approach for developing new energy ... emissions and create a cleaner economy during a policy ... York Ave. N.W. in Washington, D.C. , ... Mellon, the University of Minnesota, The Vermont Law School ...
Cached Biology News:Scripps scientists develop first examples of RNA that replicates itself indefinitely 2Scripps scientists develop first examples of RNA that replicates itself indefinitely 3Scripps scientists develop first examples of RNA that replicates itself indefinitely 4Digital communication technology helps clear path to personalized therapies 2Carnegie Mellon to unveil new sequestration plan 2
(Date:3/25/2015)... (PRWEB) March 25, 2015 An increase ... ingredients in all forms of food nutrients, regulatory changes ... a substantial rise in demand for natural astaxanthin over ... started to ramp up their capacities to satisfy the ... natural and synthetic source astaxanthin (used in nutraceuticals, aqua ...
(Date:3/25/2015)... March 25, 2015 Data from ... Mechanism of Action in Neuromuscular Diseases , ... Cytokinetics, Incorporated (Nasdaq: CYTK) announced the publication of ... troponin activator tirasemtiv in the journal Neurotherapeutics. ... “Evidence of Effect” or hypothesis-generating clinical trial which ...
(Date:3/25/2015)... March 25, 2015 Researchers at ... nanoparticle technology that will enable broader and less ... diseases with a simple breath screen. The Minnesota-based ... U.S. Food and Drug Administration (FDA) approval process ... the innovative Nanoparticle Biomarker Tagging device. , Ancon ...
(Date:3/25/2015)...  The Technology Association of Georgia ... promotion and economic advancement of Georgia,s ... of its Top 40 Innovative Technology Companies in ... group at the 2015 Georgia Technology Summit (GTS) on ... TAG,S Top 40 Awards recognize Georgia ...
Breaking Biology Technology:Global Astaxanthin Market to Reach Value of USD 1.1 billion by 2020, Expects Industry Experts in New Report Available at MarketPublishers.com 2Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 2Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 3Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 4Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 5Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 6Ancon Medical Researchers Make Nanotechnology Breakthrough for Disease Screening Technology 2Ancon Medical Researchers Make Nanotechnology Breakthrough for Disease Screening Technology 3Streamline Health, Inc. Named a TAG Top 40 Innovative Technology Company 2Streamline Health, Inc. Named a TAG Top 40 Innovative Technology Company 3Streamline Health, Inc. Named a TAG Top 40 Innovative Technology Company 4
... carbon nanotubes more than doubles the growth rate of ... everything from lifesaving medications to sweeteners to dyes and ... to show that carbon nanotubes boost plant cell division ... . Mariya V. Khodakovskaya and colleagues explain that ...
... Ga., April 4, 2012  MiMedx Group, Inc. (OTCBB: MDXG), ... regenerative biomaterials and bioimplants processed from human amniotic membrane, ... revenue goal for the first quarter of 2012. The ... $3.6 million. The Company also reported ...
... SETAUKET, N.Y., April 4, 2012 Lixte Biotechnology Holdings, ... the United States Patent and Trademark Office for its ... homologs. Dr. John Kovach, founder and president ... certain types of skin lymphomas and many other HDACi ...
Cached Biology Technology:MiMedx Exceeds Revenue Goal for First Quarter of 2012 2Lixte Biotechnology Receives US Patent for Its Proprietary Histone Deacetylase Inhibitor 2Lixte Biotechnology Receives US Patent for Its Proprietary Histone Deacetylase Inhibitor 3
Rat Aortic Endothelial Cells (RAOEC) (>500,000 cells)...
... Model 440 incorporates four channels of sophisticated ... easy-to-use instrument. Each channel consists of a ... lowpass filter, a highpass filter, a line ... control knob sets the amplifier parameters and ...
... licensed, high throughput, water bath thermal cycler capable ... microplates. This equates to 9,216 reactions per run ... arm rapidly transfers a basket of plates between ... that are considerably faster than those of peltier ...
... is a four-channel general purpose laboratory amplifier. It ... sources which may have a large common-mode level ... a high gain/low noise amplifier, an input coupling ... offset control. A control knob sets the amplifier ...
Biology Products: