Iron absorption, obesity, and colorectal cancer
Obesity is a significant risk factor for developing colorectal cancer, the second leading cause of cancer-related death in the U.S., but how obesity and colorectal cancer are linked is poorly understood. Dr. Lisa Tussing-Humphreys, assistant professor of health promotion research in the department of medicine, and her group will investigate the connection between obesity and absorption of iron in the colon and how those factors may trigger colorectal cancer. They will design a clinical trial to examine the effects of dietary iron on the risk of developing colorectal cancer in obesity.
New targets for treating thrombo-inflammatory disease
Platelets and neutrophils are blood components that play a critical role in clotting and in the development of cardiovascular disease. Jaehyung Cho, assistant professor in pharmacology and anesthesiology, and colleagues have identified an enzyme that helps regulate blood factors. They will use their pilot grant to further investigate how the enzyme may influence the formation of dangerous, artery-blocking clots.
A new approach to treating hemophilia
People with hemophilia have defective or missing clotting factors, and for them, even the smallest cut can become a medical emergency. Standard therapy--replacing missing clotting factors--is expensive and can trigger an allergic response. Dr. Xin Huang, assistant professor in the Center for Molecular Biology of Oral D
|Contact: Sharon Parmet|
University of Illinois at Chicago