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Cellular renewal process may underlie benefits of omega fatty acids
Date:2/13/2013

tophagy," says O'Rourke. "Our finding that omega-6 supplementation activated roundworms' cellular response to fasting namely autophagy even though the worms were eating normally suggests that consumption of omega-6 fatty acids may provide the benefits of caloric restriction without the need to limit food consumption. It also suggests that the reported benefits of omega-6 acids could depend in part on activation of an evolutionarily ancient program for surviving food deprivation."

O'Rourke and her co-authors note that many investigators and clinicians believe that omega-6 fatty acids commonly found in meats, poultry and vegetable oils may increase the risk of cardiovascular disease, despite epidemiologic evidence that omega-6 consumption actually reduces cardiovascular risks. "We hope that our findings made by investigating the cellular responses of a 1-millimeter roundworm will lead the scientific and medical community to look back at all the epidemiologic, basic and clinical research data and to study the effects of omega-6 fatty acids on multiple types of human cells and live animals in order to gain better knowledge on how balanced intake of these nutrients benefits human health," she says.


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Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Source:Eurekalert

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