Navigation Links
Cellular fuel gauge may hold the key to restricting cancer growth
Date:12/27/2012

lly use sugar to fuel their growth. Jones discovered that AMPK plays a specific role in restricting cancer cells' ability to use sugar to fuel their growth. "For cancer cells with low AMPK levels, their metabolism goes into overdrive," explained Prof. Jones. "They use sugar more efficiently, allowing them to grow faster. These results suggest that turning on AMPK in cancer cells may be one way that we can restrict cancer growth."

Jones' breakthrough builds on his previous discovery that the widely prescribed medication metformin, a common diabetes drug, can restrict tumour cell growth. The results bring promise that common therapeutics that turn on AMPK and alter cellular metabolism, such as metformin, may become novel tools for cancer therapy. Jones and his colleagues at McGill are currently exploring clinical applications based on this research.


'/>"/>

Contact: Russell Jones
russell.jones@mcgill.ca
514-398-3336
McGill University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study sheds light on how cells transport materials along crowded intercellular highways
2. Long-distance solute transport in trees improved by intercellular pathways in living woody tissues
3. Microchoreography: Researchers use synthetic molecule to guide cellular dance
4. New technique enables high-sensitivity view of cellular functions
5. Cellular landscaping: Predicting how, and how fast, cells will change
6. BioLife Solutions Products Now Used in More than 50 Clinical Trial-Stage Cellular Therapies
7. Newly demonstrated capabilities of low-powered nanotweezers may benefit cellular-level studies
8. Division of labor offers insight into the evolution of multicellular life
9. Researchers study knee stress at tissue, cellular levels
10. Stealthy microscopy method visualizes E. coli sub-cellular structure in 3-D
11. BUSM study shows role of cellular protein in regulation of binge eating
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/10/2015)... , April 10, 2015 ... addition of the "Security Competitive Profiles - NEC" ... http://photos.prnewswire.com/prnh/20130307/600769) , NEC will continue to supply ... to the market, with a company focus on the ... anticipated. Winning opportunities in the ...
(Date:4/8/2015)... April 8, 2015  Infinisource, a leading provider ... and Morpho, a leading supplier of biometric identification ... the market,s most advanced biometrically-enabled time clock, the ... time clock is setting a bold, new standard ... for the small and mid-size employer. When connected ...
(Date:4/2/2015)... Germany , April 2, 2015 ... fingerprint tests DERMALOG by far outperforms the strongest ... always maintaining high accuracy, the system is capable ... Hence, the speed proves up to be ten ... faster than its runner-up performance.      ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3
... of a common genetic disorder previously linked to lung ... of lung cancer, according to a report in the ... of the JAMA/Archives journals. The disorder, alpha1-antitrypsin deficiency ... affecting the U.S. population and especially those of European ...
... and precise timing, University of Oregon biologist James A. ... about the origin of embryonic cells that give rise ... of the skull and facial structures in back-boned creatures ... the Max Planck Institute of Immunology in Germany and ...
... The International Institute for Species Exploration at Arizona State ... responsible for species exploration and classification today announce ... On the list are an ornate sleeper ray, with ... dinosaur; a shocking pink millipede; a rare, off-the-shelf frog; ...
Cached Biology News:Genetic mutation associated with increased risk of lung cancer 2Origin of cells for connective tissues of skull and face challenged 2Origin of cells for connective tissues of skull and face challenged 3Scientists announce top 10 new species, issue SOS 2Scientists announce top 10 new species, issue SOS 3Scientists announce top 10 new species, issue SOS 4
(Date:4/16/2015)... OSAKA, Japan , April 16, 2015 ... of Kyoto University and Takeda Pharmaceutical Company Limited ... to develop clinical applications of induced pluripotent stem ... mellitus, neurological disorders and cancer immunotherapy. The "Takeda-CiRA ... designed to expedite multiple research projects for drug ...
(Date:4/16/2015)... San Francisco, CA (PRWEB) April 16, 2015 ... is scheduled to report first quarter results on Thursday, ... the announcement, Cytokinetics’ senior management will host a conference ... and financial results and the company’s outlook for the ... and can be accessed from the homepage and in ...
(Date:4/16/2015)... Proove Biosciences , Inc. is ... Contest for the 2015 BIO International Convention. Hosted ... International Convention will take place June 15-18 at the ... of BIO contest, industry leaders will be voting for ... conference. The community voting period began on April 14, ...
(Date:4/16/2015)... 16, 2015 Regis Technologies looks forward ... for Cancer Research (AACR) annual meeting. Regis will exhibit ... starting Saturday, April 18, in Philadelphia and running through ... title of the oldest and largest organization focused on ... grants, and partners with survivors to promote awareness and ...
Breaking Biology Technology:CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 2CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 3Cytokinetics to Announce First Quarter Results on April 30, 2015 2Cytokinetics to Announce First Quarter Results on April 30, 2015 3Proove Bisociences to Participate in the Buzz of BIO at the 2015 BIO International Convention 2Proove Bisociences to Participate in the Buzz of BIO at the 2015 BIO International Convention 3Regis Technologies Joins American Association for Cancer Research Annual Meeting 2
... OTTAWA, Canada, Sept. 21 The National Mental Health ... some type of mental illness and that 1 in ... life. By 2020, mental illness is projected to be ... an obviously staggering problem with total costs to society ...
... Bioscience to Present at 2010 UBS Global Life Sciences Conference -- N. BILLERICA, Mass., Sept. 20 ... ... (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so we need ...
... HOPKINTON, Mass., Sept. 20 Caliper Life Sciences, Inc. ... Hrusovsky, President and CEO of Caliper will be providing ... in Basel, Switzerland. This invited presentation, entitled "Next Generation ... 2010 and will highlight key trends that are transforming ...
Cached Biology Technology:Canadian Company Develops Subconscious Screening Technology 2Seahorse Bioscience to Present at 2010 UBS Global Life Sciences Conference 2Seahorse Bioscience to Present at 2010 UBS Global Life Sciences Conference 3Seahorse Bioscience to Present at 2010 UBS Global Life Sciences Conference 4Seahorse Bioscience to Present at 2010 UBS Global Life Sciences Conference 5Seahorse Bioscience to Present at 2010 UBS Global Life Sciences Conference 6Caliper Life Sciences CEO to Present Keynote Presentation at MipTec European Conference 2
DONOR BOVINE SERUM AND PLASMA...
12(S)-HETE-d8 is used as an internal standard for the quantification of 12(S)-HETE by stable isotope dilution mass spectrometry....
...
... 9(S)-HODE-d4 contains 4 deuterium atoms at the ... intended for use as an internal standard for ... spectrometry. 9(S)-HODE is produced by the lipoxygenation of ... has been detected in atherosclerotic plaques, as an ...
Biology Products: