Navigation Links
Cells 'flock' to heal wounds
Date:1/24/2013

ed us that we needed a different way to start to think about the problem."

The body marshals an astounding array of forces to heal wounds, Levine said. Many have to do with cell biology, the internal and external signals that tell a cell when to move, when to stop, when to split and when to die. His team's intent was to focus first on the cell's physical interactions with its neighbors and study what happened if all those complicating factors are eliminated from the simulations.

"We try to unravel what is physics and what is biology," Levine said. "We want to know which parts of the phenomenon don't require sophisticated signaling networks."

In the physics approach to cell motility, he said, "the first thing to do is see how far we can get if we assume that all the cells are following the same rules. Then the only thing that's creating the dynamics of the system is that they're interacting with each other. This is the type of problem that physicists have studied before, usually in nonbiological contexts."

In the Harvard experiment, he said, "They had taken a millimeter-sized tissue that was spreading and showed it wasn't just cells on the end that were pulling on the tissue while the others were spectators." But that work didn't explain how cells in the center of the tissue knew the direction of the edge.

Levine's team looked to the skies for inspiration. "Birds look around and decide which way all their neighbors are flying," Levine said. "The idea that they would move as independent birds but also coordinate is where the idea of flocking came from. This way of thinking hadn't been applied to epithelial tissue motility in wound healing."

What cells "see" are their sticky neighbors, which pull and tug them as they move on lamellipodia, thin sheets that serve as "feet" powered by actin filaments that act something like the treads on a tank. The overlapping lamellipodia of adjacent cells influence each other. "The
'/>"/>

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Retrovirus in the human genome is active in pluripotent stem cells
2. Researchers show how cells DNA repair machinery can destroy viruses
3. Enzyme helps cancer cells avoid genetic instability
4. Mature T cells can switch function to better tackle infection
5. Quadruple helix DNA discovered in human cells
6. La Jolla Institute identifies molecular switch enabling immune cells to better fight disease
7. Using snail teeth to improve solar cells and batteries
8. Scientists seek out cancer cells hiding from treatment
9. Multiple sclerosis study reveals how killer T cells learn to recognize nerve fiber insulators
10. 3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
11. After decades of research, scientists unlock how insulin interacts with cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Va. , Dec. 15, 2014 ... to make it easier to detect and prevent ... Today the agency started performing an ... capability will validate the authenticity of purchased microcircuits ... The new quality control measures will be conducted ...
(Date:12/17/2014)... -- Valencell, a leader in performance biometric data sensor ... leaders such as Intel, Jabra, Atlas, and Scosche to ... These products will be showcased at CES 2015, taking ... . "Our partners choose PerformTek biometrics, ... with the clinical data to back it up," said ...
(Date:12/17/2014)... -- Automation is fundamentally transforming the travel experience and ... borders. Over the past decade, ePassports, biometric readers, ... to self process through border control via eGates ... increasing number of airports, seaports, and land borders ... Maxine Most , Principal at Acuity Market ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... was published showing that silk produced by transgenically-engineered silkworms ... biological sciences at University of Notre Dame, exhibits the ... stronger silk could possibly be used to make sutures, ... in the Proceedings of the National Academy of ...
... insect,s internal chemicals can be converted to electricity, potentially providing ... a group of researchers at Case Western Reserve University report. ... from universities across the country that could bring the creation ... super spies out of science fiction and into reality. ...
... both the diagnosis and treatment of breast cancer, the ... a new imaging technology under investigation at the Biodesign ... subtle aberrations in cell nuclear structure, the molecular biosignature ... by providing early detection of the disease. The ...
Cached Biology News:Hybrid silkworms spin stronger spider silk 2Implanted biofuel cell converts bug's chemistry into electricity 2Implanted biofuel cell converts bug's chemistry into electricity 3Cell-CT: A new dimension in breast cancer research 2Cell-CT: A new dimension in breast cancer research 3Cell-CT: A new dimension in breast cancer research 4
(Date:12/24/2014)... (PRWEB) December 24, 2014 The report ... at 19.7% by 2019. It also provides a carefully ... strategies and challenges for the market. , Full Copy ... the report, the global market for cell expansion will ... future. It expects this growth to be driven by ...
(Date:12/24/2014)... 2014 Sigma-Aldrich Corporation (NASDAQ: ... under the Hart-Scott-Rodino Antitrust Improvements Act (HSR Act) ... 22, 2014, thereby completing the U.S. HSR Act ... of the Company by Merck KGaA, Darmstadt, Germany.  ... condition to closing the transaction, which remains subject ...
(Date:12/22/2014)... /PRNewswire/ - RepliCel Life Sciences Inc. (OTCQB: REPCF) (TSX.V: ... the development of autologous cell therapies, announced today the ... Calgary in conjunction with co-authors from Kyoto University and ... company,s ongoing clinical research using dermal sheath cup (DSC) ... The paper entitled " Hair Follicle Dermal Stem ...
(Date:12/22/2014)... Chicago, Illinois (PRWEB) December 22, 2014 ... representing tenants and occupiers of commercial real estate, has ... two new offices in Perth and Brisbane, Western Australia, ... board of directors. , ITRA Global / ACORPP ... and totally independent consultancy company providing property services to ...
Breaking Biology Technology:The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5ITRA Global Continues International Expansion in Perth and Brisbane, Australia 2
... a single atom thicknow appears to be a promising ... at the National Institute of Standards and Technology (NIST) ... of graphene layers could potentially store hydrogen safely for ... has become something of a celebrity material in recent ...
... new professional services company has been launched focused on accelerating the connections of university-based bioscience research with commercial development opportunities. Bioscience Bridge, LLC was formed ... ... , , ... ...
... March 17 Valeritas, Inc., a medical technology company committed to the development and commercialization of innovative drug delivery solutions, announced today that it has hired James E. Dentzer ... ... ... ...
Cached Biology Technology:Layered graphene sheets could solve hydrogen storage issues 2Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 2Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 3Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 4Valeritas Announces Appointment of New CFO 2Valeritas Announces Appointment of New CFO 3
Rabbit polyclonal to Vitronectin ( Abpromise for all tested applications). Antigen: Full length native Vitronectin (Cow) Entrez Gene ID: 7448 Swiss Protein ID: P04004...
... Exiqon's miRCURY LNA technology enables sensitive and ... situ hybridisation. miRCURY LNA in situ detection ... enabling the specific and sensitive detection of ... is possible in whole mounts, thin sections, ...
... E. coli Biotinylation Kit, Plasmid is designed for ... coli expression kits. (Cat. No. 3 186 148, ... provides vectors for the easy introduction of a ... protein can be enzymatically mono-biotinylated by E. coli ...
... EZ DNA Methylation Kit uses a simplified ... DNA methylation analysis. The kit is based ... place between cytosine and sodium bisulfite where ... DNA Methylation Kits innovative in-column desulphonation reaction ...
Biology Products: