Navigation Links
Cells are crawling all over our bodies, but how?
Date:10/18/2011

For better and for worse, human health depends on a cell's motility the ability to crawl from place to place. In every human body, millions of cells are crawling around doing mostly good deeds though if any of those crawlers are cancerous, watch out.

"This is not some horrible sci-fi movie come true but, instead, normal cells carrying out their daily duties," said Florida State University cell biologist Tom Roberts. For 35 years he has studied the mechanical and molecular means by which amorphous single cells purposefully propel themselves throughout the body in amoeboid-like fashion absent muscles, bones or brains.

Meanwhile, human cells don't give up their secrets easily. In the body, they use the millions of tiny filaments found on their front ends to push the front of their cytoskeletons forward. In rapid succession the cells then retract their rears in a smooth, coordinated extension-contraction manner that puts inchworms to shame. Yet take them out of the body and put them under a microscope and the crawling changes or stops.

But now Roberts and his research team have found a novel way around uncooperative human cells.

In a landmark study led by Roberts and conducted in large part by his then-FSU postdoctoral associate Katsuya Shimabukuro, researchers used worm sperm to replicate cell motility in vitro in this case, on a microscope slide.

Doing what no other scientists had ever successfully done before, Shimabukuro disassembled and reconstituted a worm sperm cell, then devised conditions to promote thecell's natural pull-push crawling motions even in the unnatural conditions of a laboratory. Once launched, the reconstituted machinery moved just like regular worm sperm do in a natural setting giving scientists an unprecedented opportunity to watch it move.

Roberts called his former postdoc's signal achievement "careful, clever work" and work it did, making possible new, revealing images of cell mot
'/>"/>

Contact: Thomas A. Roberts
roberts@bio.fsu.edu
850-644-3237
Florida State University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Simple nerve cells regulate swimming depth of marine plankton
2. Regenerating eyes using cells from hair: Stem Cells awards research into stem cell deficiency
3. Water channels in the body help cells remain in balance
4. Light can detect pre-cancerous colon cells
5. Seeking superior stem cells
6. Small molecules can starve cancer cells
7. Thin - Film Photovoltaic (PV) Cells Market Analysis to 2020 - CIGS (Copper Indium Gallium Diselenide) to Emerge as the Major Technology by 2020
8. New book on germ cells from Cold Spring Harbor Laboratory Press
9. Carnegie Mellon scientists track neuronal stem cells using MRI
10. Elsevier congratulates editors of Stem Cells: Scientific Facts and Fiction upon receipt of awards
11. Mice stem cells guided into myelinating cells by the trillions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cells are crawling all over our bodies, but how?
(Date:8/19/2014)... . Wind ... large amount of electricity is to be produced with renewable ... be stored during productive periods so that these fluctuations can ... adequate for the purpose. Science and industry are therefore working ... systems that used to be too expensive or unsophisticated to ...
(Date:8/19/2014)... at retail seafood counters in 10 different states ... consumers to unexpectedly high levels of mercury, a ... a fish of the same species, but from ... offense, according to new research by University of ... seafood is essential to allow consumers to choose ...
(Date:8/19/2014)... HOUSTON -- ( Aug. 19, 2014 ) -- Scientists ... how to pick up and transfer single cells using ... tweaked slightly. They describe this engineering feat and preliminary ... Journal of the American Chemical Society . , "Studying ... frontier in current biomedical research," said nanomedicine department. faculty ...
Breaking Biology News(10 mins):Asian inventions dominate energy storage systems 2Asian inventions dominate energy storage systems 3Seafood substitutions can expose consumers to unexpectedly high mercury 2Seafood substitutions can expose consumers to unexpectedly high mercury 3Moving single cells around -- accurately and cheaply 2
... marine vibrio bacteria discovered in the last five years, can ... in Edinburgh. , The most common disease of vibrios is ... fatality in humans. Recent interest in this genus of bacteria ... from seawater and marine animals. , New species have been ...
... professor of molecular and human genetics at Baylor College of ... in bacteria stressed by starvation, sometimes resulting in a rare ... a report in the current issue of the journal Molecular ... happens but also show that this only occurs at a ...
... Scientists from the Public Health Agency of Canada - ... of Infectious Diseases - have developed vaccines against the ... be effective in non-human primates. , In a study ... Heinz Feldmann and Dr. Steven Jones of PHAC's National ...
Cached Biology News:Stressed cells spark DNA repair missteps and speed evolution 2Researchers report breakthrough against world’s deadliest viruses 2
(Date:8/19/2014)... 19, 2014 Research and Markets  has announced the ... Strategic Business Report" report to their offering. ... Supplies in US$ Thousands by the following Product Segments: Media, Sera, ... the US, Canada , Japan ... and Latin America . Annual estimates and forecasts ...
(Date:8/19/2014)... (PRWEB) August 19, 2014 XenoTech ... fast and cost-effective metabolite production from bioactive small ... chemistry platform, the technology enables convenient and timely ... According to XenoTech’s Vice President of Commercial Operations, ... for assessing clinical risk can be measured directly ...
(Date:8/19/2014)... /PRNewswire/ - iCo Therapeutics Inc. ("iCo" or "the Company") ... its Oral Amphotericin B (Oral Amp B) drug ... by ImmuneCarta®, the immune monitoring business unit of ... Oral Amp B in reactivating latent HIV viral ... treatment with antiretroviral therapy. Memory ...
(Date:8/18/2014)... , Aug. 18, 2014 BioElectronics ... advanced consumer medical devices said that its ... interviewed by CEOLIVE.TV as part of its ... interview is available at http://ceolive.tv/bioelectronics-corp-otc-biel/biel-videos/2282-ceolive-tv-interview-bioelectronics-corp-otcqb-biel ... explains to investors the unique advantages of ...
Breaking Biology Technology:Global Cell and Tissue Culture Supplies - Strategic Business Report 2014 2Beyond Metabolite Identification, Testable Quantities Now Offered by XenoTech 2Beyond Metabolite Identification, Testable Quantities Now Offered by XenoTech 3iCo Therapeutics Announces Positive Oral Amphotericin B Study Results 2iCo Therapeutics Announces Positive Oral Amphotericin B Study Results 3BioElectronics EVP Dr. Deepak Kotak Interviewed on CEO Live 2BioElectronics EVP Dr. Deepak Kotak Interviewed on CEO Live 3
... Oct. 2 The Matan Companies has teamed up ... for the development of the National Cancer Institute,s 330,000 ... Research Park in Frederick, Maryland. The state-of-the art ... construction immediately and is slated for delivery in mid ...
... Vermillion, Inc (OTC: VRMLQ.PK) today announced that Eric Fung, M.D., ... Officer. This position will be formally held by Dr. Fung ... Chapter 11 of the U.S. Bankruptcy Code or earlier, if ... interim, Dr. Fung will work as an independent consultant. ...
... J.D. , has opened Stipkala LLC,s new office in Cincinnati, ... Stipkala LLC is an intellectual property law firm with locations ... Guttman has more than nine years of patent law experience, ... entering patent law, Dr. Guttman acquired over ten years of ...
Cached Biology Technology:Matan Companies Teams with Federal Capital Partners to Finance the National Cancer Institute at Riverside Research Park in Frederick, Maryland 2Matan Companies Teams with Federal Capital Partners to Finance the National Cancer Institute at Riverside Research Park in Frederick, Maryland 3Matan Companies Teams with Federal Capital Partners to Finance the National Cancer Institute at Riverside Research Park in Frederick, Maryland 4Vermillion Announces Return of Eric Fung, M.D., Ph.D. 2Vermillion Announces Return of Eric Fung, M.D., Ph.D. 3
... SeeDNA co-precipitant, 250 ul ... color ensures easy pellet ... acid recovery.Chemically inert, compatible ... applications.Simple 5-minute protocol. Category: ...
EDTA, 0.5 M solution, 100 ml. Ethylene diaminetetraacetic acid.Sterile, nuclease-free. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Recombinant Mouse sTNF RII/TNFRSF1B...
Mouse Wnt-11 Affinity Purified Polyclonal Ab...
Biology Products: