Navigation Links
Cell division speed influences gene architecture
Date:4/23/2014

Speed-reading is a technique used to read quickly. It involves visual searching for clues to meaning and skipping non-essential words and/ or sentences. Similarly to humans, biological systems are sometimes under selective pressure to quickly "read" genetic information. Genes that need to be read quickly are usually small, as the smaller the encoding message, the easier it will be to read them quickly. Now, researchers from Instituto Gulbenkian de Cincia (IGC, Portugal) and Centre for Molecular and Structural Biomedicine (University of Algarve, Portugal) discovered that, besides size, the gene architecture is also important to the optimization of the "reading" process. This study was now published in the open access scientific journal eLife*.

The research team led by Rui Martinho hit upon these findings while studying the earlier stages of the development in the fruit fly (scientific name, Drosophila melanogaster). It was known that the timing and coordination of the cell cycle and gene expression are crucial for normal development. In the earlier stages of development, cells divide very rapidly, but at the same time they need to correctly 'read' their genes in order to produce the required proteins. Genes contain the 'code' to produce proteins, but also contain sequences, called introns, that are not required for this process and therefore need to be removed before protein synthesis.

By reducing the efficiency of the cell machinery that removes introns, the research team observed that the failure on the "reading" only occurred in those genes that were expressed during early embryogenesis, in other words when cells were dividing rapidly. This observation lead them to the idea that the process of intron removal is time-consuming, generating a problem in highly proliferative tissues that have a narrow time window to express genes and produce proteins. The researchers confirmed this hypothesis introducing an untypical gene conta
'/>"/>

Contact: Ana Mena
anamena@igc.gulbenkian.pt
351-214-407-959
Instituto Gulbenkian de Ciencia
Source:Eurekalert  

Page: 1 2

Related biology news :

1. New key mechanism in cell division discovered
2. American Association for the Advancement of Science - Pacific Division convenes in Boise June 24-27
3. BWH launches a new research division focused on integrating systems biology and medicine
4. Division of labor offers insight into the evolution of multicellular life
5. IdentiSys acquires the Identification, Security and Presentation Divisions of Mountainland Business Systems, a Utah based reseller
6. Chromosome anchors organize DNA during cell division
7. Molecular forces are key to proper cell division
8. New insight into double-protected dance of cell division
9. Discovery of cell division master controller may improve understanding and treatment of cancer
10. Division of labor in the test tube
11. SourceMedical Announces Hiring of Clinical Expert for ASC Division
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cell division speed influences gene architecture
(Date:7/28/2014)... Amundsen became the first man to reach the South ... later, an international team of scientists led by Joe ... that air pollution from industrial activities arrived long before. ... widely spaced locations around the Antarctic continent, including the ... precise reconstruction to date of lead pollution over the ...
(Date:7/27/2014)... species of mayfly in the southern Western Ghats, a mountain ... is the first time that any mayfly belonging to the ... , The new species, called Labiobaetis soldani , "is ... contribution to the understanding of the Ephemeroptera of Palaearctic and ... describes the new mayfly in the Journal of Insect ...
(Date:7/27/2014)... data," a single computer cannot always find the solution ... across a cluster of computers that analyze a massive ... your web history to present you with targeted ads, ... book or movie. But big data is about more ... brain activity are generating unprecedented quantities of information. That ...
Breaking Biology News(10 mins):Industrial lead pollution beat explorers to the South Pole by 22 years and persists today 2Industrial lead pollution beat explorers to the South Pole by 22 years and persists today 3New tools help neuroscientists analyze 'big data' 2New tools help neuroscientists analyze 'big data' 3New tools help neuroscientists analyze 'big data' 4New tools help neuroscientists analyze 'big data' 5
... Physics (IOP) today, Tuesday 29 June 2010, announces this ... international medal, going to theoretical physicist Professor Edward Witten ... of the most influential physicists of the past 30 ... the phenomenology of particle physics and cosmology to theoretical ...
... ham radio, amateur astronomy, and early computing? Well, ... 2,000 people from around the world belong to the ... fuel cells, low-cost lab equipment, environmental surveillance, personal bio-monitoring, ... Project at the Woodrow Wilson Center is partnering with ...
... Institute for Biologically Inspired Engineering at Harvard and ... produce simple sugars and lactic acid. This innovation ... producing commodity chemicals in bulk. Their research findings ... and Environmental Microbiology . This photosynthetic factory ...
Cached Biology News:IOP announces 2010 award winners 2Harvard's Wyss Institute develops technology to produce sugar from photosynthetic bacteria 2
(Date:7/28/2014)... 28, 2014 Research and Markets has ... Market 2014-2018" report to their offering. ... is a technique used to determine the size of a ... is crucial to analyze the size of particles as it ... analysis is performed to determine the behavior and nature of ...
(Date:7/26/2014)... NY (PRWEB) July 26, 2014 ... provides key market data on the Canada Endoscopy ... millions of US dollars, volume (in units) and ... - High-End Endoscopy Visualization Systems, Mid-Range Endoscopy Visualization ... Full Report at http://www.marketresearchreports.biz/analysis/213254 . , The ...
(Date:7/25/2014)... Calif. , July 25, 2014 Amgen ... of Directors today declared a $0.61 per share dividend ... be paid on Sept. 5, 2014, to all stockholders ... Aug. 14, 2014.  About Amgen Amgen ... patients suffering from serious illnesses by discovering, developing, manufacturing ...
(Date:7/25/2014)... University of Leicester has furthered our understanding of ... create new materials using nanosized ,building blocks,. , ... prestigious academic journal Physical Review Letters , ... rich detail the structure and internal atomic motion ... and a single helium atom. , The technique ...
Breaking Biology Technology:Global Particle Size Analysis Market 2014-2018 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 3Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 5Amgen Announces 2014 Third Quarter Dividend 2Amgen Announces 2014 Third Quarter Dividend 3Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster 2Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster 3
... , , ... , , , ... highly sensitive,and specific method for the detection and quantitation,of mRNA species. ... RNA polymerases (SP6, T7,and T3). These enzymes possess several properties that,make ...
... , , ... , , , ... coli. The,enzyme has RNA-directed DNA polymerase activity,DNA-dependent DNA polymerase activity, unwinding,activity, and, ... , , , ...
... , , ... , , , Now ... sum of all,proteins encoded by a,genome at a specific stage.,Assembling the ... The reason for this is the complexity of protein,structure and function, ...
Cached Biology Technology:RNase Protection Assay (RPA),Using DIG-Labeled RNA Probes 2Increase the Power and Sensitivity for Your cDNA,Synthesis with the New Transcriptor Reverse Transcriptase 2Increase the Power and Sensitivity for Your cDNA,Synthesis with the New Transcriptor Reverse Transcriptase 3Increase the Power and Sensitivity for Your cDNA,Synthesis with the New Transcriptor Reverse Transcriptase 4Tools for Proteomic Science II 2Tools for Proteomic Science II 3Tools for Proteomic Science II 4