Navigation Links
Cell-building discovery could reduce need for some animal research
Date:2/2/2009

in September 2007 in the journal Tissue Engineering. The earlier study highlighted the invention of a 3-D Petri dish about the size of a peanut-butter cup and made of agarose, a complex carbohydrate derived from seaweed with the consistency of Jell-O. Morgan and students in his lab developed the dish, creating a product where cells do not stick to the surface. Instead, the cells self-assemble naturally and form "microtissues."

For the new research, Morgan, with students including Adam Rago and Dylan Dean, made 3-D microtissues in one 3-D Petri dish, harvested these living building blocks and then added them to more complex 3-D molds shaped either like a honeycomb, with holes, or a donut with a hole in the middle.

Those skin cells fused with liver cells in the more complex molds and formed even larger microstructures. Researchers found that the molds helped control the shape of the final microtissue.

They also found that they could control the rate of fusion of the cells by aging them for a longer or shorter time before they were harvested. The longer the wait, Morgan found, the slower the process.

Rago has since graduated from Brown, and Dean, an M.D.-Ph.D. student, has moved on from the Morgan lab to pursue his surgical rotations.


'/>"/>

Contact: Mark Hollmer
Mark_Hollmer@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. New discovery may lead to new class of allergy drugs
2. Discovery could lead to a new animal model for hepatitis C
3. Billion-year revision of plant evolution timeline may stem from discovery of lignin in seaweed
4. Cancer-causing gene discovery suggests new therapies
5. Jumbo-sized discovery made in Malaysia
6. UC Davis discovery offers hope for treating kidney cancer
7. Life Sciences Discovery Fund awards health research program grants
8. In just 5 years, gene discovery to clinical trial of potential treatment
9. Discovery of new gene associated with diabetes risk suggests link with body clock
10. Kidney function discovery sheds light on genetic complexity of disease
11. New discovery may enhance MRI scans, lead to portable MRI machines
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cell-building discovery could reduce need for some animal research
(Date:7/23/2014)... by satellite over a 15-year period off the U.S. ... feed in specific locations each year, according to a ... PLOS ONE by Ladd Irvine from Oregon ... to mitigate human threats to the whale population. , ... recover since the establishment of protections in the mid-1960s. ...
(Date:7/23/2014)... tissue samples cultured from cystic fibrosis patients, scientists at ... Lung Institute have shown that a new CF drug ... drug. , The finding, published today in the journal ... CFTR protein becomes unstable and loses its ability to ... drugs. The research offers several insights into how novel ...
(Date:7/23/2014)... , , , , , ... , , , , , ... chronic diseases and extend healthy lifespan. The idea, they argue, would be to target the... , , ... , , , , , ... , , , , , , , , ...
Breaking Biology News(10 mins):Blue whales' dangerous feeding grounds 2UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 2UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 3UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 4Strategy proposed for preventing diseases of aging 2Strategy proposed for preventing diseases of aging 3Strategy proposed for preventing diseases of aging 4Strategy proposed for preventing diseases of aging 5
... in German . The Deutsche Forschungsgemeinschaft ... new Research Units. This decision was taken by the DFG,s ... the research consortia is to offer researchers the opportunity to ... to establish innovative research directions. As with all ...
... Sandia,s decontamination foam, developed more than a decade ago ... during the 2001 anthrax attacks, is now being used ... chemical engineer in Sandia,s Chemical & Biological Systems Dept. ... renders all types of typical chemical and biological agents ...
... Ganges River ,and Irrawaddy dolphins declared by the ... study ,with Bangladesh Forest Department helped pinpoint location ... The Government of Bangladesh recently declared three new ... world,s largest mangrove ecosystem the Sundarbans, according ...
Cached Biology News:DFG to establish 4 new research units 2DFG to establish 4 new research units 3Anthrax-killing foam proves effective in meth lab cleanup 2Anthrax-killing foam proves effective in meth lab cleanup 3Anthrax-killing foam proves effective in meth lab cleanup 4New protected areas for dolphins declared 2New protected areas for dolphins declared 3
(Date:7/23/2014)... SKOKIE, Ill. , July 23, 2014 ... acid (SNA™) constructs as gene regulatory and ... Snyder has joined AuraSense Therapeutics, executive ... July 11. Prior to joining ... President and Chief Financial Officer of Cellular ...
(Date:7/23/2014)... StemGenex® , the leading resource ... aimed at improving the lives of patients dealing with ... Parkinson’s disease. StemGenex believes that a commitment to ... paramount when providing care to patients with degenerative diseases. ... therapy accessible to the millions of individuals currently living ...
(Date:7/23/2014)... 2014 Shire plc (LSE: ... specialty biopharmaceutical company, and ArmaGen, a US privately ... and collaboration agreement for AGT-182, an investigational enzyme ... both the central nervous system (CNS) and somatic ... This collaboration strengthens Shire,s rare disease pipeline of ...
(Date:7/23/2014)... N.J. (PRWEB) July 23, 2014 ... Comprehensive Cancer Center has joined its Strategic Alliance ... Strategic Alliance Partnership program, UNC Lineberger will have ... to raise awareness of its cutting-edge research initiatives, ... from UNC Lineberger will work with OncLive to ...
Breaking Biology Technology:AuraSense Therapeutics Appoints Biotechnology Veteran David S. Snyder as Chief Financial Officer 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 3Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 2Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 3Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 4Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 5OncLive Expands Its Strategic Alliance Partnership Program With the Addition of UNC Lineberger Comprehensive Cancer Center 2OncLive Expands Its Strategic Alliance Partnership Program With the Addition of UNC Lineberger Comprehensive Cancer Center 3
... on just about anything: Post-Its, a text file on my laptop, ... ,Recently, I've started trying out a free online service, Ta-Da ... track of to-do items. It was made by 37 Signals ... is why they can offer it free without any advertising. , ...
... career, Bob Weisenberg read a lot of books on management ... the way through yet another book, he realized he had ... in the software industry, Weisenberg says the way to excel ... limited number of skills, not by reading more books about ...
... you like your job (or maybe you're not wild about it) ... that keeps you glued to your desk. , ,It could also ... weather's warmer or after the Cubs opener or some other milestone. ... more of these 10 signs may tell you that your Midwest ...
Cached Biology Technology:Ta-Da Lists makes it fun to check things off 2Northwoods Software co-owner distills 30 years of business experience 2Northwoods Software co-owner distills 30 years of business experience 3Northwoods Software co-owner distills 30 years of business experience 4Ten signs tell you to look for a new tech job 2Ten signs tell you to look for a new tech job 3Ten signs tell you to look for a new tech job 4
Umbilical cord blood CD4+ T cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood MNCs and T Cells...
Human endothelial progenitor cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Dendritic Cells and EPCs...
Human monocyte-derived dendritic cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Dendritic Cells and EPCs...
...
Biology Products: