Navigation Links
Cell Transplantation reports consistent and successful islet isolations offer diabetes hope
Date:6/3/2010

Tampa, Fla. (June 3, 2010) A team of researchers from several collaborating Baylor University research centers and from Japan's Okayama Graduate School of Medicine have found a way to more consistently isolate pancreatic islet cells from brain dead donors using ductal injection (DI), a process that immediately cools donor islet cells at the injection site. The more successful islet isolation process resulted in the three type 1-diabetes patients, who received islet cell transplants, becoming insulin independent.

Their study is published in issue 19(3) of Cell Transplantation and it is now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/ .

"Inconsistent islet isolation is one of the important issues in clinical islet transplantation," said Dr. Shinichi Matsumoto, the research team's lead author. "Failure of donor islet isolation often results from the loss of the donor pancreas. Our simple modification of the retrieval process appears valuable for assuring greater success in islet transplantation."

Ductal injection is a procedure that modifies the islet isolation process using a cooling solution on the pancreatic islet cells derived from brain-dead donors. The cooling solution, applied at the donor's pancreatic ductal site, aids the viability of the islet cells.

The team successfully isolated islet cells in the DI group seven times while only three out of eight islet cell groups were isolated in the nonductal injection group. When islets from the DI group were transplanted into three type 1 diabetic patients, all three became insulin independent.

"DI significantly improved the quantity and quality of isolated islets and resulted in a high success rate of clinical islet transplantation," said Dr. Matsumoto.

According to the research team, a fifty percent success rate for clinical islet isolation has been standard; they w
'/>"/>

Contact: David Eve
celltransplantation@gmail.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2

Related biology news :

1. Novel Parkinsons treatment strategy involves cell transplantation
2. Rare genetic disease successfully reversed using stem cell transplantation
3. Ovarian transplantation: First baby is born after a new technique
4. Ovarian transplantation: New technique gives greatly improved results in this delicate operation
5. REGiMMUNE presents enhanced efficacy data in preclinical transplantation models
6. New book includes advances in the science and practice of transfusion and transplantation
7. Embryonic stem cells might help reduce transplantation rejection
8. Researchers discover link between organ transplantation and increased cancer risk
9. Stem-cell transplantation improves muscles in MD animal model, UT Southwestern researchers report
10. Clearance of hepatitis C viral infection after liver transplantation
11. New climate change reports underscore need for action
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... 2014 Research and Markets ( ... "Global Facial Recognition Market 2015-2019" report ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is a ... recognition system measures the overall facial feature of ... and the distance between eyes. Facial recognition is ...
(Date:12/11/2014)... , Dec. 10, 2014  Data Sciences ... monitoring, has released a new series of digital ... preclinical toxicology researchers. M series, part of the ... collect the best possible physiologic data when incorporating ... Adding functional endpoints to toxicology studies has evolved ...
(Date:12/10/2014)... CIE San Diego has launched an innovative ... tissue that enhances care coordination among social service and ... information; earned a second $1 million grant from the ... aging in community and; will be recognized as a ... 4-6p. CIE San Diego today announced ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... multiple sclerosis could be reversed by activating stem cells that ... has shown. Researchers from the Universities of Cambridge and ... known as myelin sheaths that protect nerve fibres ... showed how this mechanism can be exploited to make the ...
... For the first time, the barriers to breastfeeding are ... the release today of Healthy People 2020, ( http://www.hhs.gov/news/press/2010pres/12/20101202a.html ... has targeted the new 10-year goals for our nation,s ... "This is a major step forward for ...
... e-cigarettes), also called "electronic nicotine delivery systems," are ... is available on their health effects. In the ... malls in most states and on the Internet. ... this question, researchers at the University of California, ...
Cached Biology News:Study reveals new possibility of reversing damage caused by MS 2New public health goals tackle obstacles to breastfeeding success 2Electronic cigarettes are unsafe and pose health risks, UC Riverside study finds 2Electronic cigarettes are unsafe and pose health risks, UC Riverside study finds 3
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... Glasses embedded with a telescope,promise to make ... drive and do,other activities requiring sharper distance vision. ... these innovative glasses,over earlier devices in an article ... Optics, mailed to subscribers in print form this,month., ...
... NEW YORK, July 24 American Oriental,Bioengineering, Inc. (NYSE: ... release,second quarter 2008 financial results on Monday, August 11, ... a conference call at 5:00 pm ET on August ... Listeners may,access the call by dialing 1-800-599-9816 or 1-617-847-8705 ...
... July 24 Poniard,Pharmaceuticals, Inc. (Nasdaq: PARD ... that it will hold a conference call to ... corporate update,including an update on the clinical development ... McMahon, Ph.D., chairman and chief,executive officer, Ronald A. ...
Cached Biology Technology:Telescope Embedded in Spectacle Lens Promises to Make Driving Easier for Visually Impaired 2Telescope Embedded in Spectacle Lens Promises to Make Driving Easier for Visually Impaired 3Poniard Pharmaceuticals to Host Second Quarter 2008 Financial Results Conference Call on July 31 2
BAI-1 (T-20)...
MOUSE ANTI HUMAN CYTOKERATIN 1-8...
GOAT ANTI HUMAN PSA (ISOFORM 1)...
... peptide derived from the N-terminal region of ... Specificity: Specific for the N-terminus of the ... Dog Rat Mouse (positive controls: MDCK-II A431 ... heart blood vessel and brain mossy fiber ...
Biology Products: