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Cell-CT: A new dimension in breast cancer research
Date:1/5/2012

lt, the architecture imaged with Cell-CT supercedes the existing nuclear grades established for cancer diagnosis using a microscope.

Though much progress has been made in understanding the transformation of cells from normal to diseased states, patient outcomes for many forms of cancer remain discouragingly poor. Many believe a new paradigm for investigating such cancers will need to be established, and the field has drawn interested researches from diverse disciplines. Paul Davies, another co-author of the current study is a physicist and cosmologist in ASU's College of Liberal Arts and Sciences and part of a new National Cancer Institute funded consortium, devoted to studying the physical science of cancer: "We expect that insights and methods drawn from physical science will lead to radical new ideas for understanding and tackling cancer," says Davies.

The group's results provide a new window on the variations of nuclear structure that often signal cell malignancy. The unparalleled structural details produced by Cell-CT promise to dramatically improve 3-D nuclear morphometry, leading to a sensitive and specific nuclear grade classification for breast cancer diagnosis.


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Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

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