Navigation Links
Cedars-Sinai opens new Induced Pluripotent Stem Cell Core Production Facility
Date:9/29/2011

LOS ANGELES The Cedars-Sinai Regenerative Medicine Institute has opened a new Induced Pluripotent Stem Cell (iPSC) Core Facility to produce powerful cells capable of making all tissues of the body from adult human skin cells.

One of the first to open in California, cells produced by the Cedars-Sinai core will be used in research funded by the National Institutes of Health and the California Institute for Regenerative Medicine. The cells will be critical for innovative research aimed at increasing our understanding of human diseases and genetic disorders, and the quest for new treatments.

"The opening of the Cedars-Sinai Stem Cell Core Facility underscores what an exciting time this is in regenerative medicine," said Shlomo Melmed, MD, senior vice president of academic affairs and dean of the faculty at Cedars-Sinai. "It also is an example of Cedars-Sinai's deep commitment to the scientific research that will be translated into tomorrow's leading-edge treatments."

The new facility will use the latest technology to generate induced pluripotent stem cells from a patient skin scraping. The induced pluripotent stem cells can be replicated indefinitely and have biological properties similar to embryonic stem cells. These "blank slate" cells can then be turned into any kind of differentiated cell, such as a brain cell or an eye cell or a liver cell.

Although iPS cells were first produced only three years ago, they have quickly become valuable research tools. Clinicians can take skin cells from patients with specific life threatening diseases. Then, Regenerative Medicine Institute scientists can create iPS cells from them and then generate so-called "disease in a dish" models that enable them to more easily identify effective therapies.

"Now, for the first time, we can study human diseases by creating a laboratory specimen of afflicted cells," said Clive Svendsen, PhD, director of the Cedars-Sinai Regenerative Medicine Institute. "We have been funded by both the National Institutes of Health and the California Institute of Regenerative Medicine to do this work which has the potential to revolutionize medicine."

For example, the Stem Cell Core Facility already is supplying iPS cells to a five-member National Institutes of Health consortium of researchers for development of potential therapies to treat Huntington's disease, an incurable neurodegenerative genetic disorder that affects muscle coordination and some cognitive functions, such as memory. With funding from the California Institute for Regenerative Medicine, the Cedars-Sinai core has also generated iPS cells from children with spinal muscular atrophy a lethal disease that leaves children paralyzed. These are being used to develop novel drug compounds to treat this devastating disorder,

"We are very excited to launch this new core facility," said Dhruv Sareen, PhD, the core's new director. "It will enable exciting studies across the entire Cedars-Sinai Medical Center and we look forward to much productive collaboration."


'/>"/>

Contact: Sally Stewart
Sally.stewart@cshs.org
310-248-6566
Cedars-Sinai Medical Center
Source:Eurekalert

Related biology news :

1. IronKey Opens New European Office
2. Singapore opens Fusionopolis, its second major R&D hub in 5 years
3. Climate change opens new avenue for spread of invasive plants
4. Orangutans spontaneous whistling opens new chapter in study of evolution of speech
5. Registration Opens for 2009 Force Protection Equipment Demonstration
6. Unexpected finding opens up new way to stop autoimmune diseases and transplant rejection
7. A research work on molluscs nacre opens new doors for its possible use in biomedicine
8. The Earth Observatory of Singapore devoted to the study of earth sciences officially opens
9. Tiny tool to control growing blood vessels opens new potential in tumor research
10. Mobile Communication Market Opens up for Biometrics - Precise Biometrics Awarded 1st Prize at GSMA World Mobile Congress
11. Genital stimulation opens door for cryptic female choice in tsetse flies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/7/2016)... NEW YORK , Jan. 7, 2016 ... as regional markets for biometric technologies and devices, identifying ... application market for various types of biometric devices. Includes ... report to: Identify newer markets and explore the ... of biometric devices. Examine each type of biometric technology, ...
(Date:1/7/2016)... MIAMI , Jan. 7, 2016  A United ... became the first court in the country to interpret ... landmark lawsuit to go forward against the photo website ... LLP. BRIAN NORBERG vs. SHUTTERFLY, INC.; ... the plaintiff alleges that Shutterfly violates the Illinois Biometric ...
(Date:1/6/2016)... , Jan. 6, 2016 Based on ... Frost & Sullivan recognizes MorphoTrak, LLC, a U.S. ... American Frost & Sullivan Company of the Year ... scanning technology, Morpho Wave™ , has consolidated the ... fingerprint biometrics market. Morpho Wave is a ...
Breaking Biology News(10 mins):
(Date:2/4/2016)... ... February 04, 2016 , ... Shimadzu ... quad LC-MS, host live demos and poster sessions, and present on the analysis ... conference takes place March 6 to 10 at the Georgia World Congress Center ...
(Date:2/4/2016)... , Feb. 4, 2016 Beike Biotechnology, the ... medical institutions attended a ceremony in late 2015 to ... cell therapy in 2016. --> ... Translation Platform for Personalized Cell Therapy" was hosted by ... Production Center, both subsidiaries of Beike Biotechnology Co., Ltd. ...
(Date:2/4/2016)... British Columbia and MENLO PARK, Calif. ... (OTCQX: DMPI) ("DelMar" and the "Company"), a biopharmaceutical company ... today announced that it will present at the 18 ... Monday, February 8, 2016 at 10:00 a.m. EST in ... Bacha , DelMar,s president and CEO, will provide an update ...
(Date:2/4/2016)... Feb. 4, 2016 ContraVir Pharmaceuticals, Inc. (NASDAQ: ... development and commercialization of targeted antiviral therapies, announced today ... Conference 2016, to be held February 8-9, 2016, at ... 2016 Disruptive Growth & Healthcare Conference, taking place in ... 2016. James Sapirstein , Chief Executive Officer ...
Breaking Biology Technology: