Navigation Links
Cats and humans suffer from similar forms of epilepsy
Date:2/1/2013

There is something sinister about epilepsy: the disease affects the very core of our being, our brain. Epileptic attacks can lead to seizures throughout the body or in parts of it. Clouding of consciousness or memory lapses are also possible. The causes are still only partially understood but in some cases brain tumours, infections, inflammations of the brain or metabolic diseases have been implicated.

Epilepsy is not confined to humans and many animals also suffer from it. Together with partners in Oxford and Budapest, Akos Pakozdy and his colleagues at the University of Veterinary Medicine, Vienna have managed to identify the cause of a certain form of epilepsy in cats, in which the body's own immune system attacks particular proteins in the cell membranes of nerve cells. The symptoms include twitching facial muscles, a fixed stare, chewing motions and heavy dribbling. Based on their clinical experience, the researchers believe that this form of epilepsy is fairly widespread in cats. Interestingly, a highly similar type of epilepsy occurs in humans: an inflammation in the brain, known as limbic encephalitis, leads to epileptic seizures that generally manifest themselves in the arm and the facial muscles on only one side of the body.

Pakozdy and his colleagues have found antibodies in the blood of epileptic cats that react to proteins in the cell membranes of nerve cells. The proteins form the building blocks of ion channels that are involved in the production of nerve signals. The same ion channels are affected in the corresponding human form of epilepsy. They control the membrane's permeability to potassium ions based on the electric potential across the membrane, thereby helping generate the rapid nerve signals of the so-called action potential.

Immunotherapy for cats?

If the immune system attacks components of these ion channels, the production of nerve signals is disrupted. There is an increased rel
'/>"/>

Contact: Dr Akos Pakozdy
akos.pakozdy@vetmeduni.ac.at
43-664-602-576-866
University of Veterinary Medicine -- Vienna
Source:Eurekalert

Page: 1 2

Related biology news :

1. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
2. Bartonella infection associated with rheumatoid illnesses in humans
3. More than 1 way to be healthy: Map of bacterial makeup of humans reveals microbial rare biosphere
4. The Iberian wolf lives close to humans more for refuge than for prey
5. Hormone in fruit flies sheds light on diabetes cure, weight-loss drug for humans
6. Relieving plant stress could eventually help humans relax
7. Humans were already recycling 13,000 years ago
8. Pigs look healthy but test positive for flu at fairs; transmission seen between pigs and humans
9. Obese dogs at risk of health condition experienced by humans
10. Alzheimers disease in mice alleviated promising therapeutic approach for humans
11. New coronavirus has many potential hosts, could pass from animals to humans repeatedly
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/14/2015)... NEW YORK , May 14, 2015 ... specializing in identity verification and online remote ... Instructure, a software-as-a-service (SaaS) company and creator ... Shared customers of the two companies will ... Proctortrack in Canvas. As a ...
(Date:5/11/2015)... 11, 2015 Curemark LLC, a privately held ... a new Phase III double blind, randomized, placebo-controlled clinical ... CM-AT, on all children ages 3-8 with Autism. Previously, ... III double blinded clinical trial for CM-AT in children ... the digestive enzyme chymotrypsin. This new trial will help ...
(Date:5/7/2015)... GOTHENBURG, Sweden , May 7, 2015 /PRNewswire/ ... new touch fingerprint sensors, FPC1022 and FPC1035, FPC,s ... FPC1022 and FPC1035 are mainly considered for integration ... decreased size gives smartphone OEMs increased possibilities to ... portfolio. The decreased size also improves possibilities for ...
Breaking Biology News(10 mins):Verificient and Instructure Announce Alliance Partnership to Provide Online Proctoring for K-12 and Higher Education Institutions 2Curemark, LLC, Launches New Phase III Trial in Expanded Population of Children with Autism 2FPC Introduces its Smallest Touch Fingerprint Sensors to Date 2
... Venus Express has detected the molecule hydroxyl on another ... an important new tool to unlock the workings of ... molecule, is made up of a hydrogen and oxygen ... reaches of the Venusian atmosphere, some 100 km above ...
... to stave off the cognitive deficits that occur with ... published in the second issue for May of the ... Care Medicine. Researchers examined the effects green tea ... were intermittently deprived of oxygen during 12-hour night cycles, ...
... the Great Lakes with things like trout and salmon would be ... the water, so it would be natural to assume that more ... in the April journal of Ecology by the Ecological Society of ... and trout to the area has not been good for the ...
Cached Biology News:Key molecule discovered in Venus's atmosphere 2Green tea compounds beat OSA-related brain deficits 2Restoring fish populations leads to tough choice for Great Lakes Gulls 2
(Date:6/1/2015)... N.J. , June 1, 2015  The Val ... a national innovative science curriculum for high school students ... the 16 th annual LIFE Event (LPGA Pros ... Mountain Ridge Country Club in West Caldwell, ... the LPGA,s biggest stars raised more than $500,000 on ...
(Date:6/1/2015)... , June 1, 2015  Neogen Corporation (NASDAQ: NEOG ... Sterling Test House, a leading commercial food testing laboratory based ... acquired laboratory will serve as a base for the company,s ... Sterling Test House was incorporated in 1990, ... the food safety and water quality testing for major hotels ...
(Date:6/1/2015)... --  Epic Sciences, Inc. , a private diagnostics company ... and advance the treatment and management of cancer, announced ... its existing credit facility with Silicon Valley Bank ... of the facility from $5 million to $15 million ... April 1, 2019.  The availability of additional capital provides ...
(Date:6/1/2015)... 29, 2015 Research and Markets( ... the "2015 Strategies in the US ... their offering. This new 373-page ... comprehensive analysis of the POC clinical chemistry ... requirements, technological trends, competitive landscape, and emerging ...
Breaking Biology Technology:Val Skinner Foundation Announces Partnership With Discovery Education 2Neogen acquires India food safety company 2Epic Sciences Expands Silicon Valley Bank Credit Facility 2Epic Sciences Expands Silicon Valley Bank Credit Facility 3
... ... Spectrum Software announces key hire. Cindy Larkin has been hired as Director of ... her new role. , ... Southborough, MA (Vocus) November 3, 2009 -- Leading medical device and life sciences ...
... 2 BioBehavioral Diagnostics Company announced today that its ... was accepted via a rigorous peer-review process and included ... Meeting of the American Academy of Child and Adolescent ... Calvin R. Sumner, M.D., the company,s Chief Medical Officer ...
... 2 Microfluidics International Corporation (OTC Bulletin Board: MFLU), ... ended September 30, 2009. , (Logo: ... accomplishments: , Earned net income for the ... before interest, taxes, depreciation and amortization (EBITDA) Delivered ...
Cached Biology Technology:Medical Device Software Engineering Firm Full Spectrum Software Appoints Cindy Larkin to Director of Client Services 2Objective Measures of ADHD Symptoms Using the Quotient(TM) ADHD System May Reduce Cost of ADHD Drug Trials 2Objective Measures of ADHD Symptoms Using the Quotient(TM) ADHD System May Reduce Cost of ADHD Drug Trials 3Objective Measures of ADHD Symptoms Using the Quotient(TM) ADHD System May Reduce Cost of ADHD Drug Trials 4Microfluidics International Corporation Announces Third Quarter 2009 Financial Results 2Microfluidics International Corporation Announces Third Quarter 2009 Financial Results 3Microfluidics International Corporation Announces Third Quarter 2009 Financial Results 4Microfluidics International Corporation Announces Third Quarter 2009 Financial Results 5Microfluidics International Corporation Announces Third Quarter 2009 Financial Results 6Microfluidics International Corporation Announces Third Quarter 2009 Financial Results 7Microfluidics International Corporation Announces Third Quarter 2009 Financial Results 8Microfluidics International Corporation Announces Third Quarter 2009 Financial Results 9
Recorder, 6", 7 Day, 1 Pen, 0 to 100°C, 220V, 50/60 Hz, for 4520, Customer Installed...
... of the COP9 signalosome complex (CSN), a ... processes. The CSN complex is an essential ... by mediating the deneddylation of the cullin ... complex is also involved in phosphorylation of ...
... 96 well Magnetic-Ring Stand is designed for ... U-bottom microplates. The stand has a plastic ... microtiter plate footprint. The use of 96 ... and easy magnetic separation. With this magnetic ...
6B9...
Biology Products: