Navigation Links
Catch the fever: It'll help you fight off infection
Date:11/1/2011

Bethesda, MDWith cold and flu season almost here, the next time you're sick, think twice before taking something for your fever. That's because scientists have found more evidence that elevated body temperature helps certain types of immune cells to work better. This research is reported in the November 2011 issue of the Journal of Leukocyte Biology (https://www.jleukbio.org).

"An increase in body temperature has been known since ancient times to be associated with infection and inflammation," said Elizabeth A. Repasky, Ph.D., a researcher involved in the work from the Department of Immunology at the Roswell Park Cancer Institute in Buffalo, New York. "Since a febrile response is highly conserved in nature (even so-called cold blooded animals move to warmer places when they become ill) it would seem important that we immunologists devote more attention to this interesting response."

Scientists found that the generation and differentiation of a particular kind of lymphocyte, known as a "CD8+ cytotoxic T-cell" (capable of destroying virus-infected cells and tumor cells) is enhanced by mild fever-range hyperthermia. Specifically, their research suggests that elevated body temperature changes the T-cells' membranes which may help mediate the effects of micro-environmental temperature on cell function. To test this, researchers injected two groups of mice with an antigen, and examined the activation of T-cells following the interaction with antigen presenting cells. Body temperature in half of the mice was raised by 2 degrees centigrade, while the other half maintained a normal core body temperature. In the warmed mice, results showed a greater number of the type of CD8 T-cells capable of destroying infected cells.

"Having a fever might be uncomfortable," said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology, "but this research report and several others are
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Catching a breath -- wirelessly
2. Catching the West Nile virus in action
3. Hummingbirds catch flying bugs with the help of fast-closing beaks
4. Humpback whales catch prey with bubble-nets
5. NIST catch and release program could improve nanoparticle safety assessment
6. New models may reduce seabird bycatch
7. Internet catches updated butterfly and moth website
8. Arctic fisheries catches 75 times higher than previous reports: UBC research
9. Catch-up growth signals revealed
10. New research shows dolphin by-catch includes genetic relatives
11. Fishing fleet working 17 times harder than in 1880s to make same catch
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... which life arose have been maintained in our cells today ... Research published today in the Journal of Biological Chemistry ... also in animals still perform ancient reactions thought to have ... billion years ago. , The primordial soup theory suggests that ... of the combination of metals, gases from the atmosphere and ...
(Date:7/24/2014)... in mid-July 2014, as the annual fire season continues ... of increased temperatures, are heavily sprinkled across the Congo ... (northeast), and Zambia (southeast). Thick gray smoke rises from ... in the Democratic Republic of the Congo, strong winds ... season is an annual event in this region, as ...
(Date:7/24/2014)... new drug that successfully treated lupus in mice, a biomedical ... grant to expand his research to a new version of ... of autoimmune diseases., Chandra Mohan, Hugh Roy and Lillie Cranz ... a study in Arthritis Research & Therapy outlining the use ... and reduced the number of cases of lupus-related kidney disease., ...
Breaking Biology News(10 mins):Biomedical engineer looks at new applications for novel lupus drug 2Biomedical engineer looks at new applications for novel lupus drug 3
... new hope for controlling the devastating impact of Ebola ... ape die-offs first circulated widely in 2003, sceptics have ... was even the cause. The new study, led by ... doubts because it was conducted in a closely monitored ...
... have discovered that a specific human protein is essential for ... that when HIV inserts itself into a chromosome, a key ... requires a specific protein -- LEDGF/p75 (p75). This protein forms ... If the connection can be disrupted in the future, it ...
... and using the latest in imaging software and machinery, also ... have developed a fast and accurate means of tracking blood ... arteries. Researchers say it took them less than half ... used to find early warning of vessels more likely to ...
Cached Biology News:Ebola-outbreak kills 5000 gorillas 2Ebola-outbreak kills 5000 gorillas 3Mayo researchers discover HIV dependence on a human protein 2Fast test for low blood flow in dogs detects early heart trouble 2Fast test for low blood flow in dogs detects early heart trouble 3Fast test for low blood flow in dogs detects early heart trouble 4
(Date:7/23/2014)... Heroic worldwide conservation efforts have made great strides in ... in China, there are over 65 giant panda reserves ... But despite these efforts, just 1596 pandas remain in ... and zoos hope to save the panda by improving ... to the wild. Just how are these high-profile programs ...
(Date:7/23/2014)... , July 23, 2014  AuraSense Therapeutics, ... as gene regulatory and immunotherapeutic agents, announced ... joined AuraSense Therapeutics, executive leadership team as ... Prior to joining AuraSense Therapeutics, Mr. ... Financial Officer of Cellular Dynamics International Inc., ...
(Date:7/23/2014)... SAN ANTONIO , 23 de julio de ... ADBI (ADBI o la Compañía) ha anunciado hoy ... Akron (ABIA o el Instituto), ... de ADBI, un dispositivo de terapia de señal ...   El Instituto, que tiene una ...
(Date:7/23/2014)... , July 23, 2014 /PRNewswire/ - BioAmber Inc. ... company producing sustainable chemicals, today announced that the underwriters ... their option to purchase an additional 420,000 shares ... of $12.00 per share, less underwriting discounts and ... public offering of 2,800,000 shares of common stock, ...
Breaking Biology Technology:AuraSense Therapeutics Appoints Biotechnology Veteran David S. Snyder as Chief Financial Officer 2ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 2ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 3ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 4ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 5ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 6BioAmber announces exercise in full of underwriters' option in connection with previously priced follow-on offering 2BioAmber announces exercise in full of underwriters' option in connection with previously priced follow-on offering 3
... /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ: ... has successfully completed patient enrolment in its multi-centre Phase ... REOLYSIN(R) in patients with various sarcomas that have metastasized ... been enrolled in the trial. , "We are extremely ...
... /PRNewswire-FirstCall/ - BioMS Medical Corp. (TSX: MS), a leading ... announced financial and operational results for the first quarter, ... to obtain the results from MAESTRO-01, the first of ... secondary progressive multiple sclerosis, in the second half of ...
... Sky One Medical,Inc. ("China Sky One Medical" or "the ... pharmaceutical company producing over-the-counter drugs in,the People,s Republic of ... call at 10:00 a.m. Eastern Daylight Time (EDT) on ... fiscal year 2009 financial results. , ...
Cached Biology Technology:Oncolytics(R) Biotech Inc. Completes Patient Enrolment in U.S. Phase 2 Sarcoma Study 2Oncolytics(R) Biotech Inc. Completes Patient Enrolment in U.S. Phase 2 Sarcoma Study 3BioMS Medical Announces First quarter 2009 results 2BioMS Medical Announces First quarter 2009 results 3BioMS Medical Announces First quarter 2009 results 4BioMS Medical Announces First quarter 2009 results 5BioMS Medical Announces First quarter 2009 results 6BioMS Medical Announces First quarter 2009 results 7BioMS Medical Announces First quarter 2009 results 8BioMS Medical Announces First quarter 2009 results 9China Sky One Medical, Inc. Schedules Conference Call to Discuss First Quarter 2009 Results 2China Sky One Medical, Inc. Schedules Conference Call to Discuss First Quarter 2009 Results 3
WASF2 Immunogen: WASF2 (NP_008921, 73 a.a. ~ 173 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
... to ThPok ( Abpromise for all tested ... conjugated to KLH derived from within residues 500 ... the amino acid sequence is proprietary) ... Entrez Gene ID: 51043 ...
Applications: Western blotting Stability: Room temperature, indefinitely ...
Rabbit polyclonal to SUR1 ( Abpromise for all tested applications). Antigen: Synthetic peptide Entrez Gene ID: 6833 Swiss Protein ID: Q09428...
Biology Products: