Navigation Links
Carnegie's Donald Brown receives lifetime achievement award from Society for Developmental Biology
Date:2/5/2009

Baltimore, MDBiochemist, developmental biologist, and physician, Donald D. Brown of Carnegie's Department of Embryology, will receive the 2009 Lifetime Achievement Award from the Society for Developmental Biology. The award is given to "a senior developmental biologist in recognition of her/his outstanding and sustained contributions in the field[and]for the individual's excellence in research and for being a superb mentor who has helped train the next generation of exceptional scientists."

Brown has been a Carnegie staff member since 1962 and directed the Department of Embryology from 1976-1994. From 1960 to 1990 Brown studied how genes are expressed during embryonic development by purifying specific genes and reconstructing their control in the test tube. Many of these studies termed "genetics by gene isolation," took place before the recombinant DNA era and established facts about genes such as their structure, their evolution, and the signals in and around genes that control where they start and where they stop.

In 1990, Brown changed his research to a more complex problem, the control of gene expression that regulates the transformation of tadpoles into frogs. The many developmental changes that occur when a tadpole turns into a frog are controlled entirely by thyroid hormone. By studying its role in amphibian metamorphosis, Brown and colleagues developed a strategy to analyze the complexities of the hormone-gene interactions. He used thyroid hormone-induced metamorphosis in the frog Xenopus laevis to identify genes and gene pathways regulated by the hormone. This work provides the foundation for understanding how hormones control the development of organ and tissue development, growth, and death.

"Doing genetics by gene isolation gave Don Brown a firm grip on fundamental mechanisms that were beyond the classical genetics of that era," remarked Allan Spradling, director of Embryology. "Likewise his current work on metamorphosis allows access to sophisticated processes of tissue remodeling that today's researchers in the fields of stem cell biology and regenerative medicine can only dream about."

"Donald Brown has been a pivotal figure in developmental biology as a result of his path-breaking discoveries," stated Carnegie president Richard Meserve. "He also has had a major role at Carnegie through his mentoring of and assistance to his many Carnegie colleagues over the years. This award is very much deserved."

After three years at Dartmouth College, Brown received his M.D. and his M.S. in biochemistry from the University of Chicago School of Medicine in 1956. He then interned at a New Orleans hospital and became a research associate for 2 years at NIH. He later conducted research at the Pasteur Institute in France before joining Carnegie as a fellow in 1960.

Among his many affiliations, Brown is a member of the National Academy of Sciences and the American Philosophical Society. He is a fellow of the American Academy of Arts and Sciences. He organized the first Developmental Biology Gordon Conference in 1970 and has served on numerous editorial boards and visiting committees. Brown has received many awards including the 1985 Louisa Gross Horwitz Award, from Columbia University, and the 1996 E.B. Wilson Award of the American Society for Cell Biology. In 1983 he founded the Life Sciences Research Foundation, an international post-doctoral fellowship agency now in its 27th year.


'/>"/>

Contact: Tina McDowell
tmcdowell@ciw.edu
202-939-1120
Carnegie Institution
Source:Eurekalert  

Related biology news :

1. Old McDonald had a phytochemical
2. Moving in for the winter toxic brown recluse spiders pose danger
3. Men are red, women are green, Brown researcher finds
4. Brown chemist finds gray molds killer gene
5. How do bacteria swim? Brown physicists explain
6. Brown scientist finds coastal dead zones may benefit some species
7. Carnegie Mellon to receive $900,000 from EPA for brownfields research
8. Brown University and Women & Infants Hospital expand national childrens study to Bristol County
9. Brown tree snake could mean Guam will lose more than its birds
10. Brown to host conference on advances in neurotechnology
11. Brown opens institute for molecular and nanoscale innovation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Carnegie's Donald Brown receives lifetime achievement award from Society for Developmental Biology
(Date:4/3/2017)... WASHINGTON , April 3, 2017 /PRNewswire-USNewswire/ ... single-cell precision engineering platform, detected a statistically ... cell product prior to treatment and objective ... highlight the potential to predict whether cancer ... prior to treatment, as well as to ...
(Date:3/30/2017)... Trends, opportunities and forecast in this market ... (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, vein ... use industry (government and law enforcement, commercial and retail, ... others), and by region ( North America ... Pacific , and the Rest of the World) ...
(Date:3/27/2017)... , March 27, 2017  Catholic Health Services ... Management Systems Society (HIMSS) Analytics for achieving Stage ... Model sm . In addition, CHS previously earned ... hospitals using an electronic medical record (EMR). ... high level of EMR usage in an outpatient ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... ... Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO and chief research ... Inc. has been selected for membership in ARCS Alumni Hall of Fame ...
(Date:10/11/2017)... ... ... eye wash is a basic first aid supply for any work environment, but most personal ... rinse first if a dangerous substance enters both eyes? It’s one less decision, and likely ... dual eye piece. , “Whether its dirt and debris, or an acid or alkali, getting ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... announced today it will be hosting a Webinar titled, “Pathology is going digital. ... Associates , on digital pathology adoption best practices and how Proscia improves lab ...
(Date:10/11/2017)... HILLS, Calif. , Oct. 11, 2017  SkylineDx today ... (ICR) and University of Leeds ... risk-stratify patients with multiple myeloma (MM), in a multi-centric Phase ... University of Leeds is the sponsor ... and ICR will perform the testing services to include high-risk ...
Breaking Biology Technology: