Navigation Links
Carnegie's Donald Brown receives lifetime achievement award from Society for Developmental Biology

Baltimore, MDBiochemist, developmental biologist, and physician, Donald D. Brown of Carnegie's Department of Embryology, will receive the 2009 Lifetime Achievement Award from the Society for Developmental Biology. The award is given to "a senior developmental biologist in recognition of her/his outstanding and sustained contributions in the field[and]for the individual's excellence in research and for being a superb mentor who has helped train the next generation of exceptional scientists."

Brown has been a Carnegie staff member since 1962 and directed the Department of Embryology from 1976-1994. From 1960 to 1990 Brown studied how genes are expressed during embryonic development by purifying specific genes and reconstructing their control in the test tube. Many of these studies termed "genetics by gene isolation," took place before the recombinant DNA era and established facts about genes such as their structure, their evolution, and the signals in and around genes that control where they start and where they stop.

In 1990, Brown changed his research to a more complex problem, the control of gene expression that regulates the transformation of tadpoles into frogs. The many developmental changes that occur when a tadpole turns into a frog are controlled entirely by thyroid hormone. By studying its role in amphibian metamorphosis, Brown and colleagues developed a strategy to analyze the complexities of the hormone-gene interactions. He used thyroid hormone-induced metamorphosis in the frog Xenopus laevis to identify genes and gene pathways regulated by the hormone. This work provides the foundation for understanding how hormones control the development of organ and tissue development, growth, and death.

"Doing genetics by gene isolation gave Don Brown a firm grip on fundamental mechanisms that were beyond the classical genetics of that era," remarked Allan Spradling, director of Embryology. "Likewise his current work on metamorphosis allows access to sophisticated processes of tissue remodeling that today's researchers in the fields of stem cell biology and regenerative medicine can only dream about."

"Donald Brown has been a pivotal figure in developmental biology as a result of his path-breaking discoveries," stated Carnegie president Richard Meserve. "He also has had a major role at Carnegie through his mentoring of and assistance to his many Carnegie colleagues over the years. This award is very much deserved."

After three years at Dartmouth College, Brown received his M.D. and his M.S. in biochemistry from the University of Chicago School of Medicine in 1956. He then interned at a New Orleans hospital and became a research associate for 2 years at NIH. He later conducted research at the Pasteur Institute in France before joining Carnegie as a fellow in 1960.

Among his many affiliations, Brown is a member of the National Academy of Sciences and the American Philosophical Society. He is a fellow of the American Academy of Arts and Sciences. He organized the first Developmental Biology Gordon Conference in 1970 and has served on numerous editorial boards and visiting committees. Brown has received many awards including the 1985 Louisa Gross Horwitz Award, from Columbia University, and the 1996 E.B. Wilson Award of the American Society for Cell Biology. In 1983 he founded the Life Sciences Research Foundation, an international post-doctoral fellowship agency now in its 27th year.


Contact: Tina McDowell
Carnegie Institution

Related biology news :

1. Old McDonald had a phytochemical
2. Moving in for the winter toxic brown recluse spiders pose danger
3. Men are red, women are green, Brown researcher finds
4. Brown chemist finds gray molds killer gene
5. How do bacteria swim? Brown physicists explain
6. Brown scientist finds coastal dead zones may benefit some species
7. Carnegie Mellon to receive $900,000 from EPA for brownfields research
8. Brown University and Women & Infants Hospital expand national childrens study to Bristol County
9. Brown tree snake could mean Guam will lose more than its birds
10. Brown to host conference on advances in neurotechnology
11. Brown opens institute for molecular and nanoscale innovation
Post Your Comments:
Related Image:
Carnegie's Donald Brown receives lifetime achievement award from Society for Developmental Biology
(Date:10/29/2015)... 2015  Rubicon Genomics, Inc., today announced an ... its DNA library preparation products, including the ThruPLEX ... Plasma-seq kit. ThruPLEX Plasma-seq has been optimized for ... libraries for liquid biopsies--the analysis of cell-free circulating ... in cancer and other conditions. Eurofins Scientific is ...
(Date:10/29/2015)... NXTD ) ("NXT-ID" or ... the growing mobile commerce market and creator of ... leading marketplace to discover and buy innovative technology ... on StackSocial for this holiday season.   ... a biometric authentication company focused on the growing ...
(Date:10/27/2015)... , Oct. 27, 2015 In the present ... of concern for various industry verticals such as banking, ... to the growing demand for secure & simplified access ... ,sectors, such as hacking of bank accounts, misuse of ... equipment such as PC,s, laptops, and smartphones are expected ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... --> ... 2020 report analyzes that automating biobanking workflow will ... long-term samples, minimizing manual errors, improving the workflow ... errors such as mislabeling or inaccurate sample barcoding ... a vital role in blood fractionation, DNA extraction, ...
(Date:11/25/2015)... , November 25, 2015 Studies ... and human plaque and pave the way for more effective ... in cats     --> ... commonly diagnosed health problems in cats, yet relatively little was ... Two collaborative studies have been conducted by researchers from the ...
(Date:11/25/2015)... CITY , Nov. 25, 2015 /PRNewswire/ - Aeterna ... affirms that its business and prospects remain fundamentally ... , Zoptrex™ (zoptarelin doxorubicin) recently received DSMB recommendation ... to completion following review of the final interim ... Phase 2 Primary Endpoint in men with heavily ...
(Date:11/25/2015)... 2015 The Global Genomics ... professional and in-depth study on the current state ... ) , The report ... definitions, classifications, applications and industry chain structure. The ... markets including development trends, competitive landscape analysis, and ...
Breaking Biology Technology: