Navigation Links
Cardium Reports on Presentation at American Heart Association Meeting Relating to Gene Delivery to the Heart and Generx Clinical Development
Date:11/15/2010

easing levels of cardiovascular disease in emerging market countries. Our Generx product candidate could potentially be developed as a front-line therapy for patients with coronary artery disease who often do not have access to costly advanced care procedures such as coronary angioplasty and stenting, or cardiac bypass surgery."  

About Generx The Generx™ (alferminogene tadenovec, Ad5FGF-4) product candidate represents a new class of cardiovascular biologics that is being developed to leverage the body's natural healing processes in response to repeated ischemic stress (insufficient blood flow and myocardial oxygen supply due to coronary heart disease).  The natural biologic response to repeated transient ischemia is angiogenesis, the growth of new collateral blood vessels, which is orchestrated by a complex and incompletely understood cascade involving many myocardial-derived growth factors.  These newly-formed vessels can effectively augment blood flow and oxygen delivery to parts of the patient's heart downstream from a blockage in a coronary artery.  In many patients however, including those with recurrent angina, coronary collateral vessel formation is insufficient to meet the heart's needs during stress.  Currently available anti-anginal drugs, which may provide symptomatic relief, are generally designed to alter the oxygen demand of the heart muscle or dilate vessels to temporarily relieve angina.  Generx is an angiogenic therapeutic product candidate that is designed to promote the heart's natural response of collateral growth and to increase blood flow in the microcirculation. In contrast to the transient symptomatic relief by marketed anti-anginal medicines, usually taken several times a day for years, a single administration of Generx aims at modifying the disease by permanent or long-lasting structural changes in the heart.

Researchers believe that central to the biological activity and potential thera
'/>"/>

SOURCE Cardium Therapeutics
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related biology news :

1. Aware, Inc. Reports Third Quarter 2010 Financial Results
2. Smithsonian reports regional sea temperature rise and coral bleaching event in Western Caribbean
3. Novocure reports data showing TTF therapy in combination with chemotherapy has the potential to increase overall survival for patients with advanced non-small cell lung cancer
4. Terumo Medical Corp. reports first US implant in landmark study enrolling in US and Japan
5. GEN reports on the greening of the life sciences
6. Aware, Inc. Reports Second Quarter 2010 Financial Results
7. GEN reports on rediscovered technology to bolster proteomics research
8. BIO-key® Reports Strong 2010 Second Quarter and Six Month Financial Results
9. International Drug & Explosives Detection Company IDenta Corp Reports on BTK- Bullet Hole Testing Kit
10. Cell Transplantation reports consistent and successful islet isolations offer diabetes hope
11. New climate change reports underscore need for action
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... have a more effective way to control the condition, ... the National University of Singapore (NUS). , The team, ... of Pharmacology at the NUS Yong Loo Lin School ... recent PhD graduate from the Saw Swee Hock School ... common herbal-based anti-malarial drug, can be used to control ...
(Date:7/31/2014)... study of bigeye tuna movements in the northwestern Atlantic ... Pelagics Research Center at the University of Massachusetts Amherst, ... wide geographical range with pronounced north-south movements from Georges ... high-use area off Cape Hatteras southwest of Bermuda for ... approach to study one of the most important commercial ...
(Date:7/31/2014)... 100 twin pairs have identified a gene mutation that may ... hours of sleep per night. The genetic variant also ... deprivation. , Results show that a participant with p.Tyr362His ... nightly sleep duration of only five hours, which was more ... for about six hours and five minutes per night. ...
Breaking Biology News(10 mins):NUS study shows effectiveness of common anti-malarial drug in controlling asthma 2Study of bigeye tuna in Northwest Atlantic uses new tracking methods 2Study of bigeye tuna in Northwest Atlantic uses new tracking methods 3Study of twins discovers gene mutation linked to short sleep duration 2
... paleontologists have found fossilized burrows of tetrapods any land ... dating from the Early Triassic epoch, about 245 million years ... an overflowing river poured into the animals, burrows and hardened ... is about 14 inches long, 6 inches wide and 3 ...
... in Eastern Montana will now be able to chemically ... degrading begins. Paleontologists from Montana State University, North ... Natural Sciences recently bought and renovated a mobile laboratory ... for the summer. The lab is the first ...
... cell research, people are influenced by a number of ... many people. That,s the surprising finding ... who have spent the past two years studying public ... most recent issue of the International Journal of Public ...
Cached Biology News:Scientists find 245 million-year-old burrows of land vertebrates in Antarctica 2Dinosaur diggers bring mobile lab, new techniques to Eastern Montana 2Dinosaur diggers bring mobile lab, new techniques to Eastern Montana 3Scientific information largely ignored when forming opinions about stem cell research 2
(Date:8/1/2014)... , Aug. 1, 2014 One of ... rise of personalized medicine, which is the practice of ... treatments to a patient,s individual biology. Personalized diagnostics—laboratory analyses ... major role in the lab,s future. This fall, ... feature the latest science in this exciting field and ...
(Date:8/1/2014)... Once a decision has been made ... will discuss how to define your tolerance for lowest ... Allen, Senior Director of Facilities Integration at Fluor Industrial ... Industrial Services, and special guest Carrier Li, Director in ... as they provide an examination of the Conceptual Design ...
(Date:8/1/2014)... 01, 2014 Testing the mechanical ... a better understanding embryonic development. How and ... structurally and functionally distinct tissues is important because ... Prof. Todd McDevitt, Melissa Kinney, and Rabbia Saeed ... with biochemical cues to control many aspects of ...
(Date:7/31/2014)... CHICAGO , July 31, 2014 Nearly ... 65 th Annual Meeting & Clinical Lab Expo ... The meeting featured never-before-seen breakthroughs in diagnostic research and ... treatment they need. As of Wednesday, July ... 2014 AACC Annual Meeting & Clinical Lab Expo, with ...
Breaking Biology Technology:First-Ever AACC Virtual Conference to Focus on Personalized Diagnostics 2Defining Low Cost in Your Solution for Future Facilities, New Webinar for Pharma, Biotech, Medical Device and Healthcare Companies, Hosted by Xtalks 2Study Links Biomechanics and Gene Expression in Stem Cells 2Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 2Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 3
... Aug. 4 CryoLife, Inc. (NYSE: CRY ), ... Bruce G. Anderson has been promoted to vice president ... has been promoted to vice,president of international sales and ... vice president of worldwide sales and marketing.,Additionally, the company ...
... Neurobiological,Technologies, Inc. (NTI(R)) (Nasdaq: NTII ... royalty payment of approximately $2.1 million from ... for the treatment of,moderate-to-severe Alzheimer,s disease. Under ... royalty payments on certain,sales of Memantine by ...
... ALTO, Calif., Aug. 4 Anacor Pharmaceuticals,announced today that ... of Biological Research., "We are pleased to welcome ... President of Research at Anacor Pharmaceuticals. "Kurt,is a noted ... in,inflammation and his expertise will enrich our team as ...
Cached Biology Technology:CryoLife Announces Management Promotions 2CryoLife Announces Management Promotions 3Anacor Pharmaceuticals Appoints Dr. Kurt Jarnagin Vice President of Biological Research 2
... Gel loading solution, ... for non-denaturing polyacrylamide and ... nucleic acids and offers ... tracking dyes (bromphenol blue ...
Mouse polyclonal antibody to QPRT - quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))...
... PCR Optimization Kits with ammonium sulfate are ... PCR, such as Tfl, Tth, and Pfu ... performance of PCR systems in one experiment ... PCR primers into the PreMixes supplied with ...
... the needs of the biopharmaceutical ... supports fast cell growth rates ... maintaining high cell viability and ... the Baculovirus Expression Vector System ...
Biology Products: