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Cardiovascular Innovation Institute researchers receive over $2 million grant from NIH
Date:9/22/2010

ntial to revolutionize the treatment of patients with a single ventricle as the use of this device may reduce the number of surgeries from three to one or two and improve survival and clinical outcomes for these patients," Giridharan said.

By taking the workload off of the single ventricle, it may be possible to delay subsequent surgery until the patient has improved cardiac function. In some cases, the researchers said, it's possible that the device may provide patients the support they need to allow their bodies to strengthen and minimize surgeries and use of shunts, which can cause long-term heart and lung dysfunction, neurocognitive deficits, and developmental problems.

"The catheter-based pump is inserted through the skin into a blood vessel, and advanced close to the heart using a simple, minimally-invasive surgical approach," said Steven Koenig, PhD, professor of bioengineering and surgery in the CII. "Once in place, the pump expands to provide blood flow to the lungs, thereby performing the work of the missing ventricle."

The recent grant will support the investigators as they work to enhance the design of the pump, especially with regard to its deployment (collapsibility and expandability) inside the blood vessel, Giridharan said. This project is one of 12 federal and state funded grants received over the past three years totaling $8.8 million to support the work of the Division of Artificial Organs and Mechanical Circulatory Support at the CII, which is led by Mark Slaughter, MD, professor and chief of the Division of Thoracic and Cardiovascular Surgery at UofL, director of the Heart Transplant and Mechanical Assist Device program at UofL and Jewish Hospital and associate medical director of the CII. Other grants include:

  • A $1,440,170 award from the NIH and $600,000 in matching awards from the Kentucky Science and Technology Corporation (KSTC) to support the development of a device to treat early stage heart f
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Contact: Lauren Williams
lauren.williams@louisville.edu
502-852-7461
University of Louisville
Source:Eurekalert

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