Navigation Links
Cardiovascular Innovation Institute researchers receive over $2 million grant from NIH
Date:9/22/2010

Louisville, Ky. Researchers in the Cardiovascular Innovation Institute, a partnership between the University of Louisville and Jewish Hospital, in collaboration with researchers at Indiana University and Purdue University, have received a $2,027,059 grant from the National Institutes of Health to further develop an implantable pump that could dramatically improve the lives of patients with single ventricle heart disease. Single ventricle heart disease is a congenital condition in which one chamber of the heart is either missing or underdeveloped, causing an overwhelming burden on the remaining chamber to pump blood effectively.

The project is led by UofL biomedical engineer Guruprasad Giridharan, PhD, Indiana University pediatric surgeon Mark Rodefeld, MD, and Purdue University mechanical engineer Steve Frankel, PhD. It represents a collaboration between biomedical engineers in the Department of Bioengineering at UofL, who are based at the CII, and UofL's Division of Thoracic and Cardiovascular Surgery.

"Single ventricle heart disease is the leading cause of death from any birth defect in the first year of life," said Giridharan, who is UofL's principal investigator. "The children usually require three major surgeries in the first few years of life to re-route blood flow, and lighten the workload of the single ventricle, which pumps blood both to the body and lungs."

The implantable pump is designed to deliver blood to the lungs and assist the single ventricle, improving the child's circulatory status, Giridharan said.

"We have created pump prototypes of this novel and simple assist device," Giridharan said. "The funding from the NIH will enable improvement of the prototypes that will hopefully take it that much closer to implantation in humans."

This work has the potential to, at minimum, provide a crutch for patients who are undergoing the current treatment for this condition.

"This device has the pote
'/>"/>

Contact: Lauren Williams
lauren.williams@louisville.edu
502-852-7461
University of Louisville
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Significant weight-loss from surgery decreases risk for cardiovascular disease in women
2. EPA holds seminar on air pollution and cardiovascular disease
3. UH engineers to improve test for cardiovascular disease
4. CNIC and Banco Santander set up research project on early cardiovascular risk factors
5. New cancer therapy may fight cardiovascular disease
6. WPI receives $1.4 million from NIH for pioneering work on arterial plaque and cardiovascular disease
7. Shifting cellular energy metabolism may help treat cardiovascular disease
8. New nanoparticles target cardiovascular disease
9. Genetic analysis helps dissect molecular basis of cardiovascular disease
10. New study links vitamin D deficiency to cardiovascular disease and death
11. Columbia University Medical Center announces 2009 Katz Prizes in Cardiovascular Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... marginal division of the striatum is also involved ... degree of substance P in the striatal marginal ... and his team, College of Biophotonics, South China ... substance P receptor, neurokinin 1 was highly expressed ... normal rats. Unilateral or bilateral injection of an ...
(Date:7/11/2014)... brains of all vertebrates, information is transmitted through ... chemical signal to be passed from one brain ... most abundant type of synapse, can be either ... learning, memory, perception and cognition, and the balance ... function. For instance, every time we learn ...
(Date:7/10/2014)... SPRINGS, Florida , July 1, 2014 ... wallets pave way for convenience and improved security: NXT-ID, Inc. ... Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ... and MasterCard Corporation (NYSE: MA) NXT-ID, Inc., (OTCQB: NXTD) ... is pleased to announce that the second series of 30 ...
Breaking Biology News(10 mins):Blame it on the astrocytes 2Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 2Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 4Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 5
... Human Services (HHS) today announced the creation of two ... the causes of common diseases such as asthma, arthritis ... at the National Institutes of Health (NIH) for a ... of common illnesses. The other initiative launches a public-private ...
... in most cells of the body, the great majority of ... material that makes up chromosomes. Estimates are that only about ... genome are activated, or "on," at any given time in ... "off," or repressed. , Reliable gene silencing is vital to ...
... DNA causes mice to develop the metabolic syndrome, researchers ... Scientists at OHSU, the University of Texas Medical Branch ... that lack the gene encoding the DNA repair enzyme ... nearly twice the weight of their normal counterparts. The ...
Cached Biology News:Two NIH initiatives launch intensive efforts to find roots of common diseases 2Two NIH initiatives launch intensive efforts to find roots of common diseases 3Two NIH initiatives launch intensive efforts to find roots of common diseases 4Two NIH initiatives launch intensive efforts to find roots of common diseases 5Two NIH initiatives launch intensive efforts to find roots of common diseases 6Two NIH initiatives launch intensive efforts to find roots of common diseases 7Two NIH initiatives launch intensive efforts to find roots of common diseases 8New mechanism for essential genome-wide gene silencing identified 2Removing DNA repair gene causes metabolic syndrome 2Removing DNA repair gene causes metabolic syndrome 3
(Date:7/11/2014)... Cayenne Medical, Inc., a privately held ... tissue reconstruction segment, announced the worldwide launch of ... the shoulder and extremities. The SureLock System provides ... method. The unique delivery eliminates manual tensioning that ... anchor displacement (also commonly know as anchor “creep”). ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Deep ... Century Medicine Forum on ‘Commercialising Longevity Research’ and ... entrepreneurs to the London Bioscience Innovation Center for ... Foundation and Aging Analytics Ltd. The meeting highlighted ... in translational research for age-related disease, as well ...
(Date:7/10/2014)... Francisco, CA (PRWEB) July 10, 2014 ... family closer together. The Archer Family purchased a ... contained within DNA, but ended up with a lifetime ... discoveries contained within the family members’ DNA genuinely brought ... had decided to search deeper into genetic history and ...
(Date:7/10/2014)... EvoDerma ’s NOOME Anti-Aging Motion has ... now comes with a second treatment cup to help prevent ... new cup is thinner on the edges for a softer ... thin and uneven surfaces on the face, neck and décolleté. ... treatment on areas such as the cheeks and neck, or ...
Breaking Biology Technology:Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 2DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 3DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 4DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 5DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 6Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 3Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 4Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 5Introducing a New Bonus Treatment Cup for EvoDerma’s NOOME Anti-Aging Motion 2
... Mass.,  Feb. 4, 2011 The ALS ... elected Anil Godhwani, a successful Silicon Valley entrepreneur, to ... "nonprofit biotechnology" organization with a mission to discover and ... sclerosis (ALS, Lou Gehrig,s Disease). (Logo: ...
... Pharmacyclics, Inc. (Nasdaq: PCYC ) today ... second quarter that ended December 31, 2010.Recent Developments & ... Btk Inhibitor PCI-32765 in B-cell malignanciesPharmacyclics has designed a ... lymphocytic leukemia and diffuse large B-cell lymphoma to inform ...
... Boston College has been awarded a $1 million grant ... of university researchers developing a new microscope that uses ... and macroscopic matter with significantly improved clarity. The ... new class of microscopes known as "superlenses," which function ...
Cached Biology Technology:ALS Therapy Development Institute Appoints Anil Godhwani to Board of Directors 2Pharmacyclics Reports Recent Developments and Financial Results for Fiscal Second Quarter 2011 2Pharmacyclics Reports Recent Developments and Financial Results for Fiscal Second Quarter 2011 3Pharmacyclics Reports Recent Developments and Financial Results for Fiscal Second Quarter 2011 4Pharmacyclics Reports Recent Developments and Financial Results for Fiscal Second Quarter 2011 5Pharmacyclics Reports Recent Developments and Financial Results for Fiscal Second Quarter 2011 6Pharmacyclics Reports Recent Developments and Financial Results for Fiscal Second Quarter 2011 7Pharmacyclics Reports Recent Developments and Financial Results for Fiscal Second Quarter 2011 8Pharmacyclics Reports Recent Developments and Financial Results for Fiscal Second Quarter 2011 9Boston College receives W.M. Keck Foundation funding for nanoscale optical microscope 2
... is one of several isoprostanes produced from arachidonic ... renal vasoconstrictor in the rat. 8-iso PGE2 inhibits ... of 0.5 and 5 µM, respectively. When infused ... a concentration of 4 mg/kg/min, 8-iso PGE2 decreases ...
DNA Polymerase I Large (Klenow) Fragment is a DNA polymerase that lacks the 5'Cut Site3' exodeoxyribonuclease activity of intact DNA Polymerase I but it contains the 3'Cut Site5' exodeoxyribonuclease...
... offers both high-speed and high-volume versatility ... rotor options, making it ideal for a ... Versatility , High-speed (up to 15,000 ... high-volume (4 x 250mL) swinging bucket rotors ...
Guanylate Kinase Purified Anti-Mouse, Anti-Rat clone 28, Isotype Mouse IgG 1 , 50 µg Consult technical datasheet for details....
Biology Products: