Navigation Links
Cardiac cell transplant studies show promise in cardiac tissue repair
Date:9/3/2008

ema could be of paramount importance if specific combinations of differentiated cell phenotypes are to be obtained," said Severio Sartore, PhD, the study's lead author. "The study found that "the capability of both MSCs to be converted to CM-like cells (cardiomyocyte or heart muscle cells) is quite low and many cells appear with more than one nucleus"

It was unclear to researchers whether those cells had divided or fused. Furthermore, although both MSCs have "similar biological profiles" they did not possess equal differentiation potential.

"The differentiation potentials of MSCs observed in vitro need a definitive in vivo confirmation for future cell therapy experiments aimed at replenishing damaged cardiovascular tissue," concluded Sartore and his team. "While the two MSCs can contribute roughly at the same extent to capillary formation, AF-MSCs are not able to participate in the formation of arterioles and hence to vascular SMCs (smooth muscle cells)."

Sartore noted that in previous studies when AF-MSCs were transplanted into porcine models of myocardial ischemia they were converted to vascular cells, but not to cardiomyocytes.

"Both of these papers further help delineate the evolving role of bone marrow in cardiac cell therapy, not only as a regenerative means but also supportive to other cells and tissues" said Amit N. Patel, M.D., director of cardiovascular regenerative medicine and associate professor of surgery at the University of Utah School of Medicine, and a section editor for CELL TRANSPLANTATION.


'/>"/>

Contact: Tao-Sheng Li, MD, PhD
litaoshe@yamaguchi-u.ac.jp
81-836-222-260
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2

Related biology news :

1. A home early warning system for cardiac patients
2. CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics
3. Implanting embryonic cardiac cells prevents arrhythmias
4. Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery
5. University of Pittsburgh cardiologists identify new cardiac arrest gene
6. Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants
7. Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants
8. Predicting acute GVHD by gene expression could improve liver stem cell transplant outcomes
9. Researchers discover link between organ transplantation and increased cancer risk
10. Neural cell transplants may help those with Parkinsons disease
11. Stroke victims may benefit from stem cell transplants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... NEW YORK , June 30, 2015 To ... biometric security provider HYPR Corp. announced today the addition of ... will serve as board advisor and David Raviv ... to the team underscore HYPR Corp.,s commitment to providing the ... , Dimitri Sirota co-founded Layer 7 Technologies, a ...
(Date:6/26/2015)... , June 26, 2015 ATL Technology, LLC, ... devices with specialties in single use solutions, headquartered in ... MedConx, Inc. (a California corporation with ... San Jose, Costa Rica ). ... Costa Rica with ATL Technology,s existing facility in ...
(Date:6/25/2015)...  TAKE Solutions Ltd., a global business technology solutions ... Patent and Trademark Office (USPTO) for its "Method for ... Clinical Accelerators to reduce the time taken to standardize ... without the accelerators), thus reducing time to market. ... the heart of the patented Clinical Data Standardization Process ...
Breaking Biology News(10 mins):HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2TAKE Solutions Awarded Patent By USPTO 2
... which can be tolerated by large number of celiac ... as specific oat flours produced from single varieties have ... bioprocessing as well as high-pressure processing technology have been ... attributes of oat based foods. The interest ...
... dietary protein are less likely to suffer hip fractures ... according to a new study by the Institute for ... of Harvard Medical School. The study, which examined the ... Osteoporosis Study, found that individuals who were in the ...
... depths of a former copper mine in Northern California dwell ... ever discovered. The microbes members of the domain ... than other known microorganisms, rivaled in size only by a ... the outside of other cells. Their genomes, reconstructed by a ...
Cached Biology News:Novel processing technologies developed for extending use of oats in gluten-free diet 2Novel processing technologies developed for extending use of oats in gluten-free diet 3Dietary protein may reduce hip fractures in the elderly 2Weird, ultra-small microbes turn up in acidic mine drainage 2Weird, ultra-small microbes turn up in acidic mine drainage 3
(Date:7/1/2015)... NEW YORK , July 1, 2015 /PRNewswire/ ... G ), a global leader in designing, ... the Aecus Innovation Award in recognition of their ... operational efficiencies in UCB,s global business services (GBS) ... acknowledge service providers and clients that work together ...
(Date:6/30/2015)... 2015 /PRNewswire/ - Resverlogix Corp. ("Resverlogix") (TSX:RVX) announced ... Resverlogix have approved the resolutions relating to: (i) ... 5,600,000 units at a price of $2.67 per ... comprised of one common share and 0.075358 common ... CAD$15 million; and (ii) the amendment to Resverlogix,s ...
(Date:6/30/2015)... BOSTON , June 30, 2015  Juniper ... company focused on developing therapeutics that address unmet ... CFO George Elston will present at ... , Wednesday, July 8, 2015Time: , 4:45 PM ... NYWebcast (live & archive): , www.juniperpharma.com, under  ...
(Date:6/30/2015)... , ... June 30, 2015 , ... ... filter that does not sacrifice selectivity to achieve faster flow rates in comparison ... fine pores with significant open space to allow easy liquid flow while trapping ...
Breaking Biology Technology:UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 2UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 3UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 4UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 5Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 2Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 3Juniper Pharmaceuticals to Present at Cantor Fitzgerald Inaugural Healthcare Conference on July 8, 2015 2New Nanofiber Membrane Provides Fast, Efficient Filtration 2
... a robotic jellyfish, named Robojelly, which not only exhibits characteristics ... could, theoretically at least, never run out of energy thanks ... a set of smart materials, which have the ability to ... and carbon nanotubes, Robojelly is able to mimic the natural ...
... are brighter now thanks to a new study by ... Berkeley National Laboratory (Berkeley Lab). Working at the Lab,s ... provided the first experimental determination of the pathways by ... organic thin film. Their results also show how such ...
... ("AVX") is pleased to report that it has been selected as ... the Best Early-Stage Vaccine Biotech Company. The award will be announced ... AVX is pleased to be both included in ... as well as being recognized as a leader in the field. ...
Cached Biology Technology:Jellyfish inspires latest ocean-powered robot 2Better organic electronics 2Better organic electronics 3
US Pharmacopoeia Purified-Water/Water-for-Injection Quality Water...
Immunogen: Secretory component isolated from human colostrum. Storage: 4 C...
...
Medium for cryopreserving subcutaneous or omental preadipocytes...
Biology Products: