Navigation Links
Cardiac cell transplant studies show promise in cardiac tissue repair
Date:9/3/2008

ema could be of paramount importance if specific combinations of differentiated cell phenotypes are to be obtained," said Severio Sartore, PhD, the study's lead author. "The study found that "the capability of both MSCs to be converted to CM-like cells (cardiomyocyte or heart muscle cells) is quite low and many cells appear with more than one nucleus"

It was unclear to researchers whether those cells had divided or fused. Furthermore, although both MSCs have "similar biological profiles" they did not possess equal differentiation potential.

"The differentiation potentials of MSCs observed in vitro need a definitive in vivo confirmation for future cell therapy experiments aimed at replenishing damaged cardiovascular tissue," concluded Sartore and his team. "While the two MSCs can contribute roughly at the same extent to capillary formation, AF-MSCs are not able to participate in the formation of arterioles and hence to vascular SMCs (smooth muscle cells)."

Sartore noted that in previous studies when AF-MSCs were transplanted into porcine models of myocardial ischemia they were converted to vascular cells, but not to cardiomyocytes.

"Both of these papers further help delineate the evolving role of bone marrow in cardiac cell therapy, not only as a regenerative means but also supportive to other cells and tissues" said Amit N. Patel, M.D., director of cardiovascular regenerative medicine and associate professor of surgery at the University of Utah School of Medicine, and a section editor for CELL TRANSPLANTATION.


'/>"/>

Contact: Tao-Sheng Li, MD, PhD
litaoshe@yamaguchi-u.ac.jp
81-836-222-260
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2

Related biology news :

1. A home early warning system for cardiac patients
2. CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics
3. Implanting embryonic cardiac cells prevents arrhythmias
4. Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery
5. University of Pittsburgh cardiologists identify new cardiac arrest gene
6. Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants
7. Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants
8. Predicting acute GVHD by gene expression could improve liver stem cell transplant outcomes
9. Researchers discover link between organ transplantation and increased cancer risk
10. Neural cell transplants may help those with Parkinsons disease
11. Stroke victims may benefit from stem cell transplants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 15, 2014  HITLAB SM announced today its completion ... its adherence to current U.S. Food and Drug Administration ... smart device and smart phone application trials utilizing the ... "HITLAB is determined to improve global healthcare access, ...
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... "Global Facial Recognition Market 2015-2019" report to ... Facial recognition is a technology used for ... overall facial feature of a person such as nose, ...
(Date:12/11/2014)... PAUL, Minn. , Dec. 10, 2014  Data ... physiologic monitoring, has released a new series of ... of preclinical toxicology researchers. M series, part of ... toxicologists collect the best possible physiologic data when ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2
... An international team of researchers led by computer scientist ... have developed a new algorithm to sequence organisms, genomes ... new algorithm, called SPAdes, can be used to sequence ... researchers refer to as the dark matter of life, ...
... (Aug. 9, 2012) The National Space Biomedical Research Institute ... Space Life Sciences to the Massachusetts Institute of Technology and ... program allows participating students to work toward a Ph.D. that ... will each receive $1 million over a five-year period. ...
... MA -- Earthworms creep along the ground by alternately ... bodies, inching forward with each wave of contractions. Snails ... to get around, and our own gastrointestinal tracts operate ... to push food to the stomach. Now researchers ...
Cached Biology News:US-Russian collaboration develops new method for sequencing dark matter of life from a single cell 2US-Russian collaboration develops new method for sequencing dark matter of life from a single cell 3NSBRI renews space life sciences graduate programs at MIT, Texas A&M 2Soft autonomous robot inches along like an earthworm 2Soft autonomous robot inches along like an earthworm 3
(Date:1/23/2015)... Biofertilizers stimulate microbial activities in soil. ... phosphorous through the activities in the soil or in ... to the stress on reducing environmental pollution and on ... defines and segments the bio fertilizers market with analysis ...
(Date:1/22/2015)... Shimadzu Scientific Instruments today announces ... spectrophotometer. Offering wavelength scanning from 190 to 1,100 ... applications in a variety of industries, including environmental, ... UV-1280 enables intuitive operation, while the enhanced validation, ...
(Date:1/22/2015)... CAMBRIDGE, Mass (PRWEB) January 21, 2015 Cambridge ... Semantic Web technology, today announced that 2014 was a record-breaking ... expanding the capabilities of the Anzo Smart Data Platform and ... discover and utilize insights from diverse data which led to ...
(Date:1/22/2015)... January 22, 2015 Pipette.com has added ... to their comprehensive portfolio of Eppendorf products. , The ... purchase a Centrifuge 5424/5424 R and receive the following:, ... Eppendorf Research plus or Eppendorf Reference 2 , ...
Breaking Biology Technology:Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 2Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 3Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 4Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Cambridge Semantics Announces Record Results for 2014 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2
... Dane County political and economic development leaders have received two ... area Collaboration Council has surpassed the $1 million mark, and ... even greater regional challenges than Dane County. , ,The latter ... the Metro Denver Economic Development Corp ., who addressed ...
... dinners, and tuition payments compel many college students to dream ... business savvy flow naturally for some, every young capitalist needs ... Valley Technical College will host a "bus load of ... of a nationwide campus tour designed to "spread the word ...
... D.C. - There's good news for those who ... nearby Chicago. The Biotechnology Industry Organization , a ... institutions, and state biotechnology centers, has announced that it ... Windy City. , ,The 14th International Convention held in ...
Cached Biology Technology:Can Dane Co. and Wisconsin learn from Denver? 2Can Dane Co. and Wisconsin learn from Denver? 3Can Dane Co. and Wisconsin learn from Denver? 4Extreme Entrepreneur Tour coming to Fox Valley 2Extreme Entrepreneur Tour coming to Fox Valley 3