Navigation Links
Carbon monoxide may cause long-lasting heart damage
Date:1/29/2008

PROVIDENCE, R.I. Lack of oxygen isnt the only way that carbon monoxide (CO) damages the heart, say researchers at Rhode Island Hospital.

According to the findings of a new study, published in the January issue of Academic Emergency Medicine, CO also causes direct damage to the heart muscle, separate from the effects of oxygen deprivation, which reduces the hearts pumping capacity and permanently impairs cardiac function.

These findings suggest that heart damage caused by carbon monoxide may have long-lasting effects even after its been eliminated from the blood, making the diagnosis of carbon monoxide poisoning even more critical, said lead author Selim Suner, M.D., M.S., director of emergency preparedness and disaster medicine at Rhode Island Hospital.

While this research puts us one step in the right direction, there is still much more we need to know about the underlying mechanisms if we hope to someday develop targeted treatments, added Suner, whos also an associate professor of emergency medicine, surgery and engineering at The Warren Alpert Medical School of Brown University.

The study is the first to show that COs effect on heart muscle is unrelated to oxygen deprivation in the recovery phase, even when all CO is out of the system.

When inhaled, CO the leading cause of accidental poisoning deaths across the country displaces oxygen in the blood and deprives organs such as the heart, brain and other vital organs of life-sustaining oxygen. Based on previous studies, researchers have speculated that there may be other mechanisms besides oxygen deprivation that lead to CO-related heart damage, although these have not been clearly defined.

In the study, Suner and colleagues examined an animal model in which blood and other systemic factors were eliminated in order to determine the direct effects of CO on cardiac function in the recovery phase. This model used three groups: a control group; a nitrogen
'/>"/>

Contact: Jessica Collins Grimes
jgrimes2@lifespan.org
401-432-1328
Lifespan
Source:Eurekalert

Page: 1 2

Related biology news :

1. New study warns limited carbon market puts 20 percent of tropical forest at risk
2. Mice use specialized neurons to detect carbon dioxide in the air
3. Researchers find new taste in fruit flies: carbonated water
4. Studying component parts of living cells with carbon nanotube cellular probes
5. New membrane strips carbon dioxide from natural gas faster and better
6. Green alga genome project catalogs carbon capture machinery
7. Hungry microbes share out the carbon in the roots of plants
8. Decline in uptake of carbon emissions confirmed
9. Study reveals that nitrogen fertilizers deplete soil organic carbon
10. US fires release large amounts of carbon dioxide
11. Wildfire drives carbon levels in northern forests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... used techniques like X-ray crystallography and nuclear magnetic resonance ... structure of molecules, but such efforts have long been ... of a specific molecule and often in ordered and ... but impossible to peer into the structure of most ... soon be a thing of the past. , ...
(Date:4/18/2014)... researchers have published soil organic carbon sequestration rates. ... organic carbon can be sequestered by simply switching from ... there is a growing body of research with evidence ... cover crops, small grains, and forages may not be ... , "Some studies have shown that both moldboard and ...
(Date:4/18/2014)... as they,re planted may be good news for a garden. ... wild, a plant whose seeds sprouted at the first ,warm ... an insurance policy against late frosts or unexpected dry spells, ... Plants whose seeds put off sprouting until conditions are ... team of researchers working at the National Evolutionary Synthesis Center ...
Breaking Biology News(10 mins):MRI, on a molecular scale 2MRI, on a molecular scale 3Researchers question published no-till soil organic carbon sequestration rates 2Researchers question published no-till soil organic carbon sequestration rates 3Researchers question published no-till soil organic carbon sequestration rates 4Plants with dormant seeds give rise to more species 2
... for Cancer Research recognizes the first anniversary of the ... signed into law by President Obama on June 22, ... Drug Administration (FDA) to regulate the marketing, advertising and ... today include restrictions on youth access to tobacco products, ...
... why a baby,s brain is particularly flexible and why ... learn a lot? A group of researchers from the ... Dynamics and Self-Organization in Gttingen, the Schiller University in ... a new explanation: Maybe it is because the brain ...
... of our ancestors and ape cousins may suggest that humans are ... new study has found the opposite is true, with major implications ... findings suggest that early modern humans did not necessarily need to ... nuts - and perhaps less tough foods such as meat - ...
Cached Biology News:AACR recognizes 1-year anniversary of tobacco law 2Growing brain is particularly flexible 2Humans have a mighty bite 2
(Date:1/15/2014)... The Pittcon Organizing Committee is pleased to announce that Innovative ... e-Journal and producer of Food Labs Conference , ... the co-location of Food Labs Conference to be held in ... fee to attend the two-day Food Lab Conference, March 4-5. ...
(Date:1/15/2014)... ­ RedBrick Health , a fast-growing leader in ... that EmblemHealth , the New York ... providing the RedBrick Compass health assessment, combined with the ... its members. EmblemHealth is among the first health plans ...
(Date:1/15/2014)... The Microcompetition with Foreign DNA theory explains how ... latent viruses is the Epstein Barr Virus (EBV), and one ... is a chronic inflammatory disease that destroys the body’s joints. ... patients have high concentrations of EBV DNA in their bodies ...
(Date:1/15/2014)... Jan. 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") ... with R-Pharm, a leading Russian pharmaceutical company, to develop ... Russian Federation , Turkey ... (CIS). Nemonoxacin is a novel antibiotic for the treatment of ...
Breaking Biology Technology:Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4
... equipment market is poised to exceed $539 million by 2012. Consumables, ... lucrative areas that are expected to drive the industry,s growth in ... ... November 10, 2008 -- Economic trends, mergers & acquisitions in the ...
... new type of small-scale electric power generator able to ... of zinc oxide wires encapsulated in a flexible plastic ... new "flexible charge pump" generator is the fourth generation ... the piezoelectric properties of zinc oxide structures to harvest ...
... Mo., Nov. 7 In refusing to a ... removal and replacement of its,current directors, management of ... developer and manufacturer of diagnostic products whose,American Depository ... that the preservation of their jobs and positions ...
Cached Biology Technology:Calorimeters and Thermal Analysis Equipment Market to Exceed $539 Million by 2012, According to New Report by Global Industry Analysts 2Calorimeters and Thermal Analysis Equipment Market to Exceed $539 Million by 2012, According to New Report by Global Industry Analysts 3New small-scale generator produces alternating current by stretching zinc oxide wires 2New small-scale generator produces alternating current by stretching zinc oxide wires 3Trinity Biotech Management Refuses to Honor Call for a Special Meeting of Shareholders 2Trinity Biotech Management Refuses to Honor Call for a Special Meeting of Shareholders 3
... BioChains human adult normal Mega Western ... proprietary technology. The Mega Western Protein Arrays ... lysates from documented tissue sources. A protein ... well electrophoresesed along with a Protein molecular ...
... applications not requiring confocal, the BD Pathway ... the Pathway 435. And, the Pathway 415 ... applications require it. High-performance, ... to use the laser autofocus, camera autofocus, ...
fully automated system for the processing of microarrays on microscope slides...
... containing Dermal Fibroblasts (rabbit) and media. Cryo-preserved ... 10% DMSO at passage 25 (approx), supplied ... cell culture is supplied as a long-term ... additional 6 months of continuous growth from ...
Biology Products: